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Strong association of common variants in the IGF2BP2 gene with type 2 diabetes in Lebanese Arabs
منشور في 2012"…Taking the common rs4402960/rs1470579 GA haplotype as reference, multivariate analysis confirmed the positive association of TC (P = 0.009; OR, 1.43; 95%CI, 1.09–1.87), and TA (P < 0.001; OR = 5.49; 95%CI = 2.09–14.39) haplotypes with increased T2DM risk. These differences remained significant after applying the Bonferroni correction for multiple testing. …"
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Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank
منشور في 2021"…This study reports an association between amylase gene CN and adiposity traits in a large Middle Eastern population. …"
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The Paget's disease of bone risk gene <i>PML</i> is a negative regulator of osteoclast differentiation and bone resorption
منشور في 2022"…<p dir="ltr">Paget's disease of bone (PDB) is characterized by focal increases in bone remodelling. Genome-wide association studies identified a susceptibility locus for PDB tagged by rs5742915, which is located within the PML gene. …"
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Toxicity assessment of di(2-ethylhexyl) phthalate using zebrafish embryos: Cardiotoxic potential
منشور في 2024"…Although DEHP showed negligible influence on the length and pericardial area of exposed embryos, it led to multiple bodily deformities. Gene expression analyses of key cardiogenic and inflammatory genes evidenced alterations in tbx20, bcl2, and il1b expression in Zebrafish embryos at 96 h post-fertilization. …"
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
منشور في 2019"…MicroRNA expression was determined by quantitative polymerase chain reaction and tested for significant changes after surgery.</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">BMI decreased by 3.8 kg/m<sup>2</sup> 21 days postoperatively. …"
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Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
منشور في 2020"…ResultsHIC and HUC groups showed significantly decreased NP test scores in various domain compared to CHNM. …"
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
منشور في 2022"…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. …"
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Transcriptome analysis of Escherichia coli K1 after therapy with hesperidin conjugated with silver nanoparticles
منشور في 2021"…Significant regulation was observed for metabolic genes and several genes involved in the coordination of flagella. …"
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Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury
منشور في 2021"…Band area and intensity ratios, band frequency and bandwidth values of specific spectral bands showed that TBI causes significant structural and contextual global changes including decrease in carbonyl content, unsaturated lipid content, lipid acyl chain length, membrane lipid order, total protein content, lipid/protein ratio, besides increase in membrane fluidity with an altered protein secondary structure and metabolic activity in hippocampus 24 h after injury. …"
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Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis
منشور في 2024"…No significant changes were observed on IOP with mannitol administration when comparing vitrectomized versus non- vitrectomized eyes.…"
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Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury
منشور في 2021"…Significant decrease in methyl content and a significant increase in olefinic content were observed in Co and CC regions of mTBI rat brain tissues. …"
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). Concurrently, Ex-4 significantly lowered the expression levels of De novo lipogenesis genes such as SREBP-1, SCD-1and ACC. …"
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Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta...
منشور في 2023"…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. …"
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Positional and dimensional temporomandibular joint osseous changes in patients treated with the forsus fatigue resistant device: a non-randomized clinical trial
منشور في 2025"…In the treatment group, condylar width decreased significantly by 0.52 ± 0.92 mm, in contrast to an increase of 0.17 ± 0.35 mm in the control group (<i>P</i> = 0.010). …"
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The Effect of Treated Waste-Water on Compaction and Compression of Fine Soil
منشور في 2016"…The significant effect was observed in swell index and swelling pressure of the soils. …"
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