Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

“…Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …”
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Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties by Slimani, Ahmed

“…However, the density decreased significantly with increasing the calcination temperature above 850 °C due to the secondary phase formation. …”
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A genome-wide transcriptomic analysis of embryos fathered by obese males in a murine model of diet-induced obesity by Laura Bernhardt (14152842)

“…This analysis revealed significant upregulation of the Samd4b and Gata6 gene in embryos in response to a paternal HFD. …”

Investigation of positive education implementation and its impact on students' wellbeing and academic self-efficacy in K-12 private schools in Dubai by KHREIBI, RIMA ABOU

“…The findings revealed the following: 1) in recent years there has been increasing positive education implementation grounding in the recent international, national, local, and educational authority policies and initiatives. 2) absence of standardised local and school policy related to positive education implementation has led to the need for adaptability of positive education implementation across school. 3) there has been strong engagement of the internal school community (teachers, school leaders and students) with external school community (parents). 4) significant changes in the overall level DSWC indicators associated with social emotional wellbeing, life satisfaction, perseverance, feeling safe, and belonging to school. 5) insignificant changes associated with DSWC indicators associated with emotional regulation, happiness, optimism, academic self-concept, cognitive engagement, engagement (flow), peer belonging and school climate. 6) PASS assessment factors show increase in wellbeing, motivation and self-efficacy for regulation and decrease in academic self-efficacy. 7) significant increase in emotional, social wellbeing and academic self-efficacy among students due to positive education implementation as perceived by teachers, parents, and students.…”
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The effect of malva sylvestris on inflammation, gastric damage, lipemia, glycemia and microbial growth. (c2006) by Sleiman, Na'ama Hassan

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A population study of clinically actionable genetic variation affecting drug response from the Middle East by Puthen Veettil Jithesh (12040358)

“…The allele frequencies of 1,320 variants in 703 genes affecting 299 drugs or class of drugs were significantly different between the Qatari population and other world populations. …”

Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods by Charbel Al Khoury (13167975)

“…Consequently, resistant pests reduce the yield of agricultural production, causing significant economic losses and reducing food security. …”

Fermentation-induced modifications to the structural, surface, and functional properties of quinoa proteins by Mohammad Alrosan (20089263)

“…Using advanced analytical techniques, such as ultraviolet, fluorescence, and FT-IR spectra, it has been demonstrated that fermented QPs exhibit significant structural changes (P < 0.05) compared to unfermented QPs. …”

An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im... by Khreibi, Rima Abou

“…In terms of United Arab Emirates University (UAEU), there has been a decrease in STEM programs enrolment, while STEM graduates in UAEU has stayed steady at 1/3 STEM majors compared to 2/3 non-STEM programs. …”
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Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis by Osama Hussein (21301202)

“…For OAG patients, the pooled effect showed an IOPR% of 18.94% with a significant absolute change of −4.35 mmHg, <i>p</i> < 0.001 at 12 months, and IOPR% of 16.95% with an absolute IOP change of −3.83 mmHg, <i>p</i> < 0.001 at 24 months. …”

Evaluating the impact of the Minimization of Aggression and Violence (MoAV) intervention on mechanical restraint use in Qatar's acute mental health setting by Ananth Nazarene (21239912)

“…The percentage of restrained patients decreased from 25 % to 4 %, p = (<0.001). The mean duration of restraint incidents slightly increased from 59.1 min in 2016 to 61.3 min in 2021, though this change was not statistically significant. …”

On the benefits of sleep by Nature Research (16552612)

“…People who work nights are exposed to artificial light, and this significantly affects the expression of “clock genes” that synchronize body functions to the day–night cycle. …”

Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation by Bartholomew, Aaron

“…Increasing complexity appeared to lead to decreasing beetle widths. 9 beetle species were relatively rare in, or absent from, the higher complexity treatments, including 5 of the 6 largest species. 2 rare, small beetle species were only found in higher complexity treatments. …”
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Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment by Seán Fitzgerald (721911)

“…Low TRIM28 epithelium to stroma ratios were associated with elevated levels of caspases 3 and 7 in stroma (p = 0.041 and p = 0.036) and an increased signaling pathway similarity in stromal cells with 81 significant Spearman correlations (ρ ≥ 0.75, p ≤ 0.01).…”

Frugal innovation for sustainable rural development by Mokter, Hossain

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G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome by Francesco Casciello (18557613)

“…CDH10 overexpression significantly reduces cellular movements in breast cancer cell lines and prevents the hypoxia-mediated increase in cell motility. …”

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways by Khaled W. Sadek (14153196)

“…More significantly, WPS provokes a down- and up-regulation of E-cadherin and focal adhesion kinase (FAK), respectively, which are important key regulators of cancer progression genes. …”

Symptoms of depression and anxiety in anorexia nervosa by Mattar, Lama

“…The relationship between these clinical manifestations and the biological changes caused by starvation is not well understood. …”
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels by Haya Al-Sulaiti (5449256)

“…<p dir="ltr">Nanoparticles (NP) have gained significant attention in biomedical research due to their unique properties and potential applications in drug delivery, imaging, and diagnostics. …”

The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function by MUBARAK, ALIA MARJAN

“…It may assist policymakers of the Dubai government to develop and implement systematic changes into the current risk management processes. …”
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