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Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis
Published 2022“…<em>BUB1B</em> also showed a highly significant positive correlation with <em>FOXM1</em> in all the TCGA cancer types. …”
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Investigating the suitability of poly tetraarylphosphonium based anion exchange membranes for electrochemical applications
Published 2021“…Proton-/cation-exchange membranes (which conduct positive charged ions such as H+ or Na+) have historically been used in many devices such as fuel cells, electrolysers, and redox flow batteries. …”
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Serum immune mediators as novel predictors of response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients with high tissue-PD-L1 expression
Published 2023“…Moreover, correlation analysis showed significant positive linear correlation of soluble PD-L1 (sPD-L1) with higher TPD-L1 expression. …”
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Genotypic and phenotypic characterization of candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin. (c2018)
Published 2018“…Candida albicans is both a commensal and a significant opportunistic fungal human pathogen, present in the digestive tract and the mouth as a part of the normal human microflora. …”
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Comprehensive analysis of LncRNAs expression profiles in an in vitro model of steatosis treated with Exendin-4
Published 2021“…</p><h3>Results</h3><p dir="ltr">We confirm that Ex-4 improves steatosis in HepG2 cells. We found 379 and 180 differentially expressed LncRNAs between untreated and steatotic cells and between steatotic and Ex-4-treated steatotic cells, respectively. …”
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Harnessing piperine for enhanced antimicrobial activity of carbon dot‑modified cellulose fibers
Published 2024“…The antibacterial properties of the CDs were tested on cellulose discs, demonstrating strong adherence and significant inhibition of bacterial cells. The cytotoxicity studies showed that these CDs, at concentrations up to 0.1 mg/mL, and the CD-modified fibers are benign to mammalian cells, emphasizing their safety for human use. …”
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Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy
Published 2020“…Analysis of HLA-A*0201 responses revealed a significant T cell activation after stimulation with peptide pools 2 (PP2) and 8 (PP8). …”
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“Effectiveness of Text Messaging Intervention on Intuitive Eating
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The link between glycemic control measures and eye microvascular complications in a clinical cohort of type 2 diabetes with microRNA-223-3p signature
Published 2023“…Discovery analysis identified 20 differentially expressed miRNAs in T2D compared to controls, of which miR-223-3p was significantly upregulated (fold change:5.16, p = 3.6e−02) and positively correlated with glucose and hemoglobin A1c (HbA1c) levels (p-value = 9.88e−04 and 1.64e−05, respectively), but did not show any significant associations with insulin or C-peptide. …”
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Light chain amyloidosis presenting with autoimmune hepatitis-primary sclerosing cholangitis overlap syndrome
Published 2020“…Her liver enzymes (Alkaline phosphatase, Alanine aminotransferase, Aspartate aminotransferase had decreased significantly.</p><h3>Conclusions</h3><p dir="ltr">AL amyloidosis can very rarely present as AIH-PSC overlap syndrome, manifesting with raised liver enzymes, biliary strictures, pruritis and positive liver antibodies. …”
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Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer
Published 2015“…By IHC assays, we found that IBC patients displayed a higher number of NFAT5-positive cases than nIBC (69.2% vs. 19.5%; p-value = 2.79 10-7). …”
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Effect of consanguinity on birth weight for gestational age in a developing country
Published 2007“…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …”
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden
Published 2021“…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …”
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Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
Published 2017“…These findings have significant policy implications for the provision of guidance to policymakers in identifying optimal energy mixes and in pursuing realistic goals to enhance renewable energy penetration and to contribute to the current efforts of tackling climate change.…”
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…Adaptive periodic based manual cleaning approach where a changing cleaning period is fixed for each season based on significant variations of seasonal averages from the performance based manual cleaning approach, taken as 1 standard deviation from the season average. 3. …”
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The pro-apoptotic effect of kefir in malignant T-lymphocytes involves a p53 dependent pathway
Published 2013“…Results: Previous work in our lab has shown the anti-proliferative effect of kefir in both HTLV-1 negative as well as HTLV-1 positive leukemic cell lines with no significant cytotoxic effect on normal lymphocytes. …”
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…Flow cytometry analysis revealed that treatment with 10 μg/ml HC significantly increased the number of cells undergoing late apoptosis (28%), while 25 μg/ml caused a larger cell shift towards late apoptosis (46.6%) and necrosis (39%). …”
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Ultrasound Triggered Release of Estrone- Targeted Liposomes
Published 2017Get full text
doctoralThesis