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Showing 181 - 200 results of 291 for search '(( significant ((change decrease) OR (largest decrease)) ) OR ( significant potential agent ))', query time: 0.22s Refine Results
  1. 181

    Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice by Julie Decock (44558)

    Published 2015
    “…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …”
  2. 182

    The Importance of Acetonitrile in the Pharmaceutical Industry and Opportunities for its Recovery from Waste by McConvey, Ian F.

    Published 2012
    “…Azeotropic distillation was found to be the most likely approach to recovering acetonitrile from aqueous waste streams. Several potential breaking agents were assessed against a range of selection rules based on residue curve maps, determined using the Universal Functional Activity Coefficient (UNIFAC) method, and potential processing issues. …”
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  3. 183

    Frugal innovation for sustainable rural development by Mokter Hossain (14634969)

    Published 2023
    “…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”
  4. 184

    Aorta deformation linked to heart disease by Nature Research (16552612)

    Published 2015
    “…They found that the mechanics of the aorta were altered, with the pulsatile change in aortic diameter, distention and elasticity of the aortic walls being significantly decreased, and aortic stiffness significantly increased, in HCM patients compared to the controls. …”
  5. 185

    Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain by Mohamed H. M. Ali (5768066)

    Published 2018
    “…</p><p dir="ltr"><br></p><h3>Results</h3><p dir="ltr">The FTIR results revealed that in the lesioned gray matter the relative distribution of lipid, lipid acyl and protein contents decreased significantly. Also at this locus, there was a significant increase in aggregated protein as detected by high-levels Aβ1-42. …”
  6. 186

    A Sociodemographic Analysis of the Impact of COVID-19-Related Schools’ Closure on the Diet and Physical Activity of Children and Adolescents in Qatar by Muna Abed Alah (14779534)

    Published 2023
    “…Higher parental educational levels, maternal employment, and having a positive family history of obesity and/or overweight in first-degree relatives were significantly associated with adverse lifestyle changes during schools’ closure.…”
  7. 187

    Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... by Parkes J Kendrick (9714851)

    Published 2021
    “…Although global age-standardised prevalence of smoking tobacco use decreased significantly between 1990 and 2019 (annualised rate of change: –1·21% [–1·26 to –1·16]), similar progress was not observed for chewing tobacco (0·46% [0·13 to 0·79]). …”
  8. 188
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  10. 190

    Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway by Shilpa Kuttikrishnan (3520079)

    Published 2023
    “…Natural products, like the fungal metabolite neosetophomone B (NSP‐B), have emerged as potential therapeutic agents due to their bioactive properties. …”
  11. 191

    Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie by Echtay, Akram

    Published 2017
    “…The percentage of persons who achieved the target of HbA1c<7% increased from .7% at baseline to 39% at week 24. Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …”
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  12. 192

    Rituximab and Pirfenidone in the Treatment of Steroid‐Refractory Bleomycin Lung Injury by Aasir M. Suliman (14150217)

    Published 2025
    “…The addition of rituximab and pirfenidone led to significant clinical and radiological improvement, highlighting the potential role of these agents in managing steroid‐refractory BILI.…”
  13. 193

    Structure-activity relationships of copper-based metal-organic Frameworks: Investigating antibacterial mechanisms against gram-positive and gram-negative bacteria by Muhammad Hubab (20639153)

    Published 2025
    “…Overall, the study highlights the broad-spectrum potential of Cu-MOFs, making them strong candidates for developing active antimicrobial agents in the future, such as antibiotics.…”
  14. 194

    Plasma neurological biomarkers as a measure of neurotoxicity in pediatric dental general anesthesia: a prospective observational feasibility study by S. Chakithandy (21841454)

    Published 2024
    “…Such concerns are largely based on animal studies, historical anesthetic agents, and assessment tools, thus warranting further investigations. …”
  15. 195

    Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar by Shuja Mohd Reagu (12051406)

    Published 2022
    “…</p><h3>Conclusions</h3><p dir="ltr">The rates of Obsessive–compulsive symptoms were increased and the rates of intent to breastfeed were decreased when compared with pre pandemic rates. The obsessive–compulsive symptoms and the intent to not breastfeed were significantly associated with fear of infection to the new-born. …”
  16. 196

    GLP-1 receptor agonists, are we witnessing the emergence of a paradigm shift for neuro-cardio-metabolic disorders? by Abdelilah Arredouani (10914455)

    Published 2025
    “…The <u>neuroprotective </u>attributes of GLP-1 RAs have garnered significant interest, with research indicating their potential to alleviate cognitive decline associated with <u>neurodegenerative diseases</u>. …”
  17. 197

    Structure-Activity Relationships of Copper-Based Metal-Organic Frameworks: Investigating Antibacterial Mechanisms against Gram-Positive and Gram-Negative Bacteria by Muhammad Hubab (20639153)

    Published 2025
    “…Overall, the study highlights the broad-spectrum potential of Cu-MOFs, making them strong candidates for developing active antimicrobial agents in the future, such as antibiotics.…”
  18. 198

    Implementation of corporate governance rules and procedures in lebanese firms by Elgammal, Walid

    Published 2014
    “…Consequently, the purposes of this study are: 1) Present a summary of the most significant changes and framework of corporate governance of firms in developing/emerging countries. 2) Provide a summary of the most significant developments in Lebanon concerning corporate governance, including disclosure and framework. 3) Assess the outcomes obtained on the level of corporate governance disclosure practices and scores among 30 of the leading enterprises in Lebanon. …”
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  19. 199

    Impact of pharmacy-led medication reconciliation on admission to internal medicine service by Karaoui, Lamis R.

    Published 2019
    “…The most common discrepancies consisted of medication omission (71.8%), and the most common agents involved were dietary supplements (27.7%). …”
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  20. 200

    Harnessing piperine for enhanced antimicrobial activity of carbon dot‑modified cellulose fibers by Ravindran, Sreeshna

    Published 2024
    “…This study focused on synthesizing phenylboronic-acid-functionalized piperine-based carbon dots (PBA-PPCDs) and boronic acid carbon dots (BACDs) as potential antimicrobial agents. The materials were successfully synthesized using a hydrothermal method and characterized using various techniques to confirm the size, charge, fluorescence properties, and inner morphology of the CDs. …”
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