Image 1_Non-chemotherapy drugs inducing agranulocytosis: a disproportionality analysis based on the FAERS database.pdf by Shanshan Wu (348762)

“…Notably, NCDIA-associated mortality rates showed a significant decrease from 11.91% (2004–2010) to 7.28% (2021–2024) (P < 0.001).…”

Supplementary file 1_Full-dose versus reduced-dose comparison of direct oral anticoagulants for extended treatment of venous thromboembolism: a systematic review and meta-analysis... by Renshu Zhang (22775495)

“…</p>Conclusion<p>Reduced-dose DOACs were associated with a significant decrease in the risk of major bleeding/CRNMB compared with full-dose DOACs, but were not associated with a significant increase in the risk of recurrent VTE. …”

Image 5_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”

Image 3_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”

Supplementary file 1_Phase angle as a predictor of prolonged length of hospital stay and adverse outcomes in elderly medical inpatients: a retrospective cohort study.docx by Jia Liu (41593)

“…Adverse event rates across the PhA tertiles (T1–T3) were 32.9%, 18.6%, and 5.6%, respectively, indicating a significant decrease in event incidence as PhA values increased. …”

Data Sheet 1_Deep crustal composition and Late Paleozoic geotectonic evolution in West Junggar, China.pdf by Shenglin Xu (12076840)

“…During the Early Permian-Early Triassic period (272–250 Ma), magmatic activity decreased significantly, where the southwestern region experienced high-temperature, low-pressure, crustal thinning extension. …”

<b>Characterizing the role of PP2AB'' family subunits in mechanical stress response and plant development through calcium and ABA signaling in </b><b><i>Arabidopsis thaliana</i></b... by Hyuk Sung Yoon (19985262)

“…Transcriptome analysis showed a significant decrease in the expression of <i>CYP707A3</i>, a gene potentially targeted by VIP1 that regulates abscisic acid (ABA) catabolism, in the <i>atb''αβγδ</i> mutant compared to wild type leaves. …”

Data Sheet 3_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Table 2_The impact of the herd health interventions in small ruminants in low input production systems in Ethiopia.docx by Mesfin Mekonnen Moliso (19920393)

“…Generally, the intervention impact analysis revealed that morbidity rate was significantly decreased (p = 0.009) in intervention years (6.31% in 2018 to 3.02% in 2021) and that herd health interventions provide an added value.…”

Image_1_What can be observed in intervertebral cartilage endplate with aging? An animal model study of excessive axial mechanical loading.PNG by Zhouyang Hu (8410554)

“…MRI analysis revealed significant degenerative changes in the loaded Co8/9 CEP, including decreased signal intensity and the formation of Schmorl’s nodes at 8 and 12 weeks. …”

Data Sheet 1_Global burden, trends, and inequalities in cancer and subtypes attributable to high BMI among older adults, 1990–2021: a secondary analysis of the global burden of dis... by Yitong Huang (6991481)

“…Background<p>High body mass index (BMI) is a significant modifiable risk factor for cancer, yet its global burden in older adults (aged ≥60 years) remains incompletely understood.…”

Table 5_Symptoms and sleep characteristics of tic disorder children with allergic diseases: a case–control study.docx by Zhang Panpan (22335250)

“…Among them, the impairment scale score, total tic score, and sleep-disordered breathing score of the allergic rhinitis group were significantly increased (all p < 0.05); in the allergic conjunctivitis group, the total motor score and total tic score increased significantly, and the daytime sleepiness score decreased significantly (all p < 0.05). …”

Table 3_Symptoms and sleep characteristics of tic disorder children with allergic diseases: a case–control study.docx by Zhang Panpan (22335250)

“…Among them, the impairment scale score, total tic score, and sleep-disordered breathing score of the allergic rhinitis group were significantly increased (all p < 0.05); in the allergic conjunctivitis group, the total motor score and total tic score increased significantly, and the daytime sleepiness score decreased significantly (all p < 0.05). …”

Table 1_Symptoms and sleep characteristics of tic disorder children with allergic diseases: a case–control study.docx by Zhang Panpan (22335250)

“…Among them, the impairment scale score, total tic score, and sleep-disordered breathing score of the allergic rhinitis group were significantly increased (all p < 0.05); in the allergic conjunctivitis group, the total motor score and total tic score increased significantly, and the daytime sleepiness score decreased significantly (all p < 0.05). …”

Table 6_Symptoms and sleep characteristics of tic disorder children with allergic diseases: a case–control study.docx by Zhang Panpan (22335250)

“…Among them, the impairment scale score, total tic score, and sleep-disordered breathing score of the allergic rhinitis group were significantly increased (all p < 0.05); in the allergic conjunctivitis group, the total motor score and total tic score increased significantly, and the daytime sleepiness score decreased significantly (all p < 0.05). …”

Table 2_Symptoms and sleep characteristics of tic disorder children with allergic diseases: a case–control study.docx by Zhang Panpan (22335250)

“…Among them, the impairment scale score, total tic score, and sleep-disordered breathing score of the allergic rhinitis group were significantly increased (all p < 0.05); in the allergic conjunctivitis group, the total motor score and total tic score increased significantly, and the daytime sleepiness score decreased significantly (all p < 0.05). …”

Table 4_Symptoms and sleep characteristics of tic disorder children with allergic diseases: a case–control study.docx by Zhang Panpan (22335250)

“…Among them, the impairment scale score, total tic score, and sleep-disordered breathing score of the allergic rhinitis group were significantly increased (all p < 0.05); in the allergic conjunctivitis group, the total motor score and total tic score increased significantly, and the daytime sleepiness score decreased significantly (all p < 0.05). …”

Neurochemical identity of dFB^23E10Ո^84C10 neurons. by Joseph D. Jones (13883524)

“…A Kruskal–Wallis ANOVA followed by Dunn’s multiple comparisons revealed that acutely silencing VGlut-AD; 84C10-DBD and 84C10-AD; ChAT-DBD neurons significantly decreases sleep. ****<i>P</i> < 0.0001. …”

Data Sheet 1_Intratumoral microbiota composition in women’s cancers: a systematic review and meta-analysis.docx by Qin Wen (3505655)

“…Of the 22 studies investigating α-diversity in women’s cancers, disease-free controls, and those with benign conditions, notable changes in diversity indices were observed. Compared to adjacent normal tissues, the Simpson index significantly decreased in breast cancer (SMD = -0.75, 95% CI: [-0.94, -0.55]) and endometrial cancer (SMD = -0.83, 95% CI: [-1.37, -0.28]). …”

Data Sheet 2_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…Compared with those in the placebo group, the levels of several bile acids were significantly greater in the SY-009-treated groups. Moreover, the proportion of free bile acids decreased significantly, the proportion of glycine-conjugated bile acids increased significantly, the proportion of taurine-conjugated bile acids tended to be stable, and PBA/SBA significantly increased after SY-009 administration.…”