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Showing 121 - 140 results of 282 for search '(( significant ((changes decrease) OR (larger decrease)) ) OR ( significant challenge cell ))', query time: 0.11s Refine Results
  1. 121

    Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels by Haya Al-Sulaiti (5449256)

    Published 2024
    “…<p dir="ltr">Nanoparticles (NP) have gained significant attention in biomedical research due to their unique properties and potential applications in drug delivery, imaging, and diagnostics. …”
  2. 122
  3. 123

    Pharmacological interventions targeting β-adrenoceptors in colorectal cancer: an evolving paradigm by Aya Ghosn (22997230)

    Published 2025
    “…<p dir="ltr">Colorectal cancer (CRC) is a significant global health challenge, ranking as the third most common cancer and the second leading cause of cancer-related deaths worldwide. …”
  4. 124

    Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

    Published 2020
    “…Finally, only in lower sumac dose, significant decreases in methylation status of three out of five gene promoters–ATM, PTEN, and TIMP3 (PITX2 and RASSF1 promoters were not changed). …”
  5. 125

    Therapeutic Impact of P-PENT, P-HEX and 5CLSS (IV) Platinum (IV) complexes on Acute Myeloid Leukemia in vitro and in vivo by Bou Chacra, Joelle

    Published 2025
    “…A significant increase in ROS production was also observed upon cell treatment with the complexes. …”
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    masterThesis
  6. 126

    Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

    Published 2016
    “…Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …”
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    article
  7. 127

    Fermentation-induced modifications to the structural, surface, and functional properties of quinoa proteins by Mohammad Alrosan (20089263)

    Published 2025
    “…Using advanced analytical techniques, such as ultraviolet, fluorescence, and FT-IR spectra, it has been demonstrated that fermented QPs exhibit significant structural changes (P < 0.05) compared to unfermented QPs. …”
  8. 128

    Qatar’s immigrants at higher risk of diabetes by Nature Research (16552612)

    Published 2015
    “…The researchers stress, however, that their preliminary results should be confirmed in future studies involving larger numbers of participants. 1 “We would advise the Qatari government to screen all immigrants entering the country, as this would decrease the risk of unnecessary complications due to the late diagnosis of diabetes,” says lead author Dennis Mook-Nakamori. …”
  9. 129

    An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat... by Merheb, Caroline

    Published 2022
    “…As this stands, this study attempt to solve three questions: (1) what are the changes and their significance that the soil management systems impose on soil properties? …”
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    masterThesis
  10. 130

    An optimized xylene-free protein extraction method adapted to formalin-fixed paraffin embedded tissue sections for western blot analysis by Mansour, Anthony G.

    Published 2017
    “…Deparaffinization of formalin-fixed paraffin embedded (FFPE) tissues with xylene currently remains a major challenge to the biomedical community. We developed an efficient xylene-free protocol to isolate proteins from archived FFPE human tissue sections. …”
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  11. 131

    Fault Diagnosis Based Machine Learning and Fault Tolerant Control of Multicellular Converter Used in Photovoltaic Water Pumping System by B. Rouabah (17947820)

    Published 2023
    “…<p dir="ltr">Currently, providing water in developing countries, especially in dry and hot rural areas, is a significant challenge. However, creating new electric grids is often expensive. …”
  12. 132

    Natural products as chemo-radiation therapy sensitizers in cancers by Sabah Nisar (12561961)

    Published 2022
    “…Unfortunately, treatment failure due to intrinsic and acquired resistance to the current CT and RT is a significant challenge associated with poor patient prognosis. …”
  13. 133

    Symptoms of depression and anxiety in anorexia nervosa by Mattar, Lama

    Published 2014
    “…The relationship between these clinical manifestations and the biological changes caused by starvation is not well understood. …”
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  14. 134
  15. 135

    Preparation of Mesoporous/Microporous MnCo<sub>2</sub>O<sub>4</sub> and Nanocubic MnCr<sub>2</sub>O<sub>4</sub> Using a Single Step Solution Combustion Synthesis for Bifunction Oxy... by Anchu Ashok (14152020)

    Published 2020
    “…Chronoamperometric (CA) runs for 24 h shows excellent stability of MnCo<sub>2</sub>O<sub>4</sub> without any significant decrease in the current or potential value in ORR and OER. …”
  16. 136

    The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer by Ettaib El Marabti (23276158)

    Published 2018
    “…These isoforms and their encoded proteins are not insignificant byproducts of the abnormal physiology of cancer cells, but either drivers of cancer progression or small but significant contributors to specific cancer hallmarks. …”
  17. 137

    Predictive Power of Random Forests in Analyzing Risk Management in Islamic Banking by Ahmet Faruk Aysan (11902115)

    Published 2024
    “…Findings reveal that larger banks provide more consistent survey responses, driven by their confidence and larger survey budgets. …”
  18. 138

    Competition vs cooperation: An agent based model for sustainable tomatoes’ import system by Sarah Namany (17268922)

    Published 2024
    “…Based on the research findings, a competitive global market can bring economic benefits to Qatar as an importing nation, but this approach also entails substantial <u>water consumption</u> and results in significant environmental emissions. Conversely, collaboration among exporting countries demonstrates a potential 20% reduction in water usage and a 15% decrease in environmental emissions compared to the competitive scenario, offering enhanced environmental performance albeit at<u> higher economic costs</u>. …”
  19. 139

    Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice by Julie Decock (44558)

    Published 2015
    “…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …”
  20. 140

    The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function by MUBARAK, ALIA MARJAN

    Published 2018
    “…It may assist policymakers of the Dubai government to develop and implement systematic changes into the current risk management processes. …”
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