Search alternatives:
significant changes » significant challenge (Expand Search)
changes decrease » largest decrease (Expand Search), change increases (Expand Search)
larger decrease » marked decrease (Expand Search)
significant changes » significant challenge (Expand Search)
changes decrease » largest decrease (Expand Search), change increases (Expand Search)
larger decrease » marked decrease (Expand Search)
-
6361
Image 1_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff
Published 2025“…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.</p>Conclusion<p>While loss of p35 resulted in minor changes in phenotype, there were decreases in ARG-1 production and STAT3 phosphorylation, increased metabolism, and dramatically reduced antigen processing by M0, M1 or M2. …”
-
6362
Depletion of viral UL87 LTF in late infection does not affect viral long promoter transcription.
Published 2025“…<b>(B)</b> UCSC Genome Browser of the MIE promoter/enhancer and downstream region show that dTag degrader treatment significantly decreased transcription from the LTF-dependent UL124 promoter and enhancer promoter EP2 (gold arrowheads). …”
-
6363
Full name and abbreviation.
Published 2025“…</p><p>Results and conclusion</p><p>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group’s SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”
-
6364
Table 2_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx
Published 2025“…Peripheral NK and CD8+ T cells were decreased dose-dependently. Interestingly, spinal cord infiltrating NK cells increased with low-dose tofacitinib, though no other changes in neuroinflammation were observed. …”
-
6365
The animal experimental protocol.
Published 2025“…</p><p>Results and conclusion</p><p>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group’s SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”
-
6366
Supplementary Material for: Race/Ethnic Differences in In-Hospital Mortality after Acute Ischemic Stroke
Published 2024“…Introduction: Stroke mortality has declined, with differential changes by race; stroke is now the 5th leading cause of death overall, but 2nd leading cause of death in Black individuals. …”
-
6367
Image 3_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff
Published 2025“…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.</p>Conclusion<p>While loss of p35 resulted in minor changes in phenotype, there were decreases in ARG-1 production and STAT3 phosphorylation, increased metabolism, and dramatically reduced antigen processing by M0, M1 or M2. …”
-
6368
Table 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx
Published 2025“…Peripheral NK and CD8+ T cells were decreased dose-dependently. Interestingly, spinal cord infiltrating NK cells increased with low-dose tofacitinib, though no other changes in neuroinflammation were observed. …”
-
6369
Data Sheet 1_Allicin ameliorates acute myocardial infarction in rats by modulating calcium homeostasis in cardiomyocytes through the induction of hydrogen sulfide production.docx
Published 2025“…</p>Results<p>The results indicate that allicin significantly enhanced cardiac function, raised H<sub>2</sub>S levels in myocardial tissue and serum, reduced necrosis tissue size, decreased myocardial enzyme levels, and improved myocardial pathological changes. …”
-
6370
Data Sheet 1_Effect of high intakes of protein-only and carbohydrate-only on plasma metabolites and hormones, in addition to nitrogen excretion.xlsx
Published 2025“…Interestingly, the GLP-1 response was larger following PRO and remained elevated after 240 minutes, whereas the GIP response was larger following CHO. …”
-
6371
Table_1_Differential microbiome features in lake–river systems of Taihu basin in response to water flow disturbance.xlsx
Published 2024“…Additionally, migration and dispersal rates of microbes in the ET region, along with the impact of dispersal limitations, were significantly higher than in the ST region. High flow disturbances notably reduced microbial niche width and overlap, decreasing the complexity and stability of microbial coexistence networks. …”
-
6372
Image_1_Differential microbiome features in lake–river systems of Taihu basin in response to water flow disturbance.pdf
Published 2024“…Additionally, migration and dispersal rates of microbes in the ET region, along with the impact of dispersal limitations, were significantly higher than in the ST region. High flow disturbances notably reduced microbial niche width and overlap, decreasing the complexity and stability of microbial coexistence networks. …”
-
6373
Spatial variation and clgassification of anthropogenic soils formed by long-term “<i>Dorotsuke”</i> soil-dressing in Andosols of the Omiya Upland along the Arakawa River, Japan
Published 2025“…The two anthropogenic horizons exceeded 50 cm in thickness with different soil textures, while one of the other two showed significant mixing with Andosol. The profiles exhibited a vertical attenuation of andic characteristics, including increased bulk density, decreased short-range-order mineral content, and reduced phosphate retention, from the buried Andosol up to the topsoil. …”
-
6374
Data Sheet 1_The six-year decomposition of coarse woody debris drives shifts in soil fungal communities in subtropical forests.docx
Published 2025“…While global climate change is expected to exacerbate forest disturbances and lead to a significant accumulation of CWD, the effect of CWD decomposition on the composition, diversity and functional traits of soil fungal communities remains unclear, especially for subtropical forests with high tree species diversity.…”
-
6375
Table 1_The global burden of otitis media in 204 countries and territories from 1992 to 2021: a systematic analysis for the Global Burden of Disease study 2021.docx
Published 2025“…Trend analysis was conducted using estimated annual percentage change (EAPC), Joinpoint regression, age-period-cohort, and decomposition analyses. …”
-
6376
-
6377
-
6378
India-Asia collisional processes: constraints from the Eocene magmatic rocks in the southern Tibetan Plateau
Published 2025“…<p>The India-Asia collision has been one of the most significant geological events on Earth over the last 100 Ma. …”
-
6379
-
6380
Comparison of opioid use among long-term care residents in Ontario and Alberta, Canada: A multi-jurisdictional, repeated cross-sectional study
Published 2025“…In both provinces, there were significant decreases in higher risk opioid prescribing over time, including concurrent use with benzodiazepines, but also significant increases in the concurrent use with gabapentinoids and tramadol use (Alberta only).…”