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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
changes decrease » largest decrease (Expand Search), change increases (Expand Search)
larger decrease » marked decrease (Expand Search)
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14821
Table 8_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog...
Published 2025“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”
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14822
Presentation 1_Combination of αCD4 antibody and retinal antigen injection induces long-term disease control in autoimmune uveitis.pptx
Published 2025“…Flow cytometry was employed to analyze immune cell infiltration, and RNA sequencing of ocular tissue was performed to assess gene expression changes.</p>Results<p>Mice receiving aCD4 antibody and IRBP1-20 showed sustained disease control up to 28 weeks, with reduced ocular inflammation, less retinal damage on OCT, and decreased immune cell infiltration compared to untreated controls. …”
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14823
Table 3_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.xlsx
Published 2025“…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …”
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14824
Table9_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx
Published 2024“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”
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14825
Presentation 1_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.pptx
Published 2025“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”
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14826
Image 1_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif
Published 2025“…The age-standardized incidence rate (ASIR) experienced a decline of 1.07% from 1990 to 2021, while the age-standardized prevalence rate (ASPR) decreased by 0.95%. The incidence of EMT peaked among women aged 20–24 years, whereas mortality rates increased with advancing age. …”
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14827
Table 1_Molecular and epigenetic responses to crowding stress in rainbow trout (Oncorhynchus mykiss) skeletal muscle.xlsx
Published 2025“…Background<p>Chronic stress is a critical challenge in fish aquaculture, adversely affecting growth, health, and overall productivity. Among the most significant chronic stressors in intensive farming is crowding, which triggers the release of cortisol, the primary stress hormone in fish. …”
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14828
Table7_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx
Published 2024“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”
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14829
Image 3_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.tif
Published 2025“…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …”
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14830
Table 1_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.xlsx
Published 2025“…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …”
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14831
Image 3_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif
Published 2025“…The age-standardized incidence rate (ASIR) experienced a decline of 1.07% from 1990 to 2021, while the age-standardized prevalence rate (ASPR) decreased by 0.95%. The incidence of EMT peaked among women aged 20–24 years, whereas mortality rates increased with advancing age. …”
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14832
Table6_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx
Published 2024“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”
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14833
original data.xlsx
Published 2024“…<b>Research Results</b>: The results showed that the levels of inflammatory factors significantly decreased in the blood purification treatment group after treatment, with a notable reduction in hospitalization and ICU stay duration compared to the conventional treatment group. …”
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14834
DataSheet1_Interannual temperature rise leads to more uniform phenological matching between invasive Stellera chamaejasme and pollinators across elevations.pdf
Published 2024“…<p>Exploring how environmental changes induce alterations in the phenology matching between plants and pollinators is significant for predicting species’ reproductive output and population dynamics. …”
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14835
Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf
Published 2025“…Significant differences were also found between responders and non-responders in the first-order radiomic feature Energy.…”
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14836
Image2_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.png
Published 2024“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”
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14837
Table 2_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.xlsx
Published 2025“…To evaluate its therapeutic potential, we administered exogenous carnosine in both models and assessed its effects on body weight, inflammatory cytokine expression, and histopathological changes.</p>Results<p>Carnosine supplementation significantly improved body weight maintenance, reduced the expression of pro-inflammatory cytokines, and attenuated histological lung damage in both LPS- and papain-induced lung injury models. …”
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14838
Image1_Diverse responses of hypoxia-inducible factor alpha mRNA abundance in fish exposed to low oxygen: the importance of reporting methods.PDF
Published 2024“…<p>Low dissolved oxygen (hypoxia) poses significant challenges to aquatic ecosystems, affecting the behavior, reproduction, and survival of aquatic organisms. …”
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14839
Data Sheet 1_Trifolin inhibits the calcium-driven contraction pathway in vascular smooth muscle.pdf
Published 2025“…<p>Trifolin, a bioactive component of the Qingda granule, has demonstrated significant antihypertensive potential; however, its precise mechanisms of action remain largely unknown. …”
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14840
Supplementary file 1_Prolonged effect of antibiotic therapy on the gut microbiota composition, functionality, and antibiotic resistance genes’ profiles in healthy stool donors.zip...
Published 2025“…No significant increase in clinically important ARGs was detected.…”