Glucose and G-6-P levels modulate HK2-<i>SOX10</i> mRNA association and <i>SOX10</i> mRNA translation. by Ana Luisa Dian (22258504)

“…<p><b>(A)</b> Western blot analysis of HK2 and SOX10 protein level in A375 cells cultured for 24 h with decreasing concentrations of glucose or under glucose starvation, as indicated. …”

Table1_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... by Wenlei Wang (1514554)

“…Subgroup analysis revealed that FFYH improved the recovery time of clinical symptoms, improved hematological parameters, and controlled excessive cytokine storms to a greater extent in the mild COVID-19 male subgroup, abnormal hematology subgroup, and 32–42-year-old subgroup than in the corresponding LHQW subgroup (P < 0.05). No patients progressed to severe or critical cases.</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”

Table2_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... by Wenlei Wang (1514554)

“…Subgroup analysis revealed that FFYH improved the recovery time of clinical symptoms, improved hematological parameters, and controlled excessive cytokine storms to a greater extent in the mild COVID-19 male subgroup, abnormal hematology subgroup, and 32–42-year-old subgroup than in the corresponding LHQW subgroup (P < 0.05). No patients progressed to severe or critical cases.</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”

Glucagon-like peptide 1 receptor agonists modestly reduced low-density lipoprotein cholesterol and total cholesterol levels independent of weight reduction: a meta-analysis and met... by Frederick Berro Rivera (12679463)

“…</p> <p>GLP-1RA treatment modestly decreased LDL-C and TC but did not significantly affect triglycerides, VLDL-C, or HDL-C.…”

Data Sheet 1_Efgartigimod for generalized myasthenia gravis in the extreme elderly (≥80 years): a multicenter retrospective real-world study.pdf by Ye Hong (2580841)

Baumer-TPW_2023_Dopamine-Monocytes_PMID37251548.xlsx by Tiffany Powell-Wiley (18098425)

“…Furthermore, Filamin A (FLNA), a</p><p dir="ltr">prominent actin-crosslinking protein, that is known to regulate CCR2 recycling, significantly decreased in DA-</p><p dir="ltr">treated NCM (p < 0.05), indicating a reduction of CCR2 recycling. …”

Protein and gene expression levels of p62 and LC3B in miR-7974 mimic-transfected MCF-7 cells. by Stralina Eneh (21213312)

“…Representative western blots were cropped from respective western blot images for the protein of interest and grouped together. <b>(B)</b> The fold change of p62 and <b>(C)</b> LC3BI between negative control/cell-only samples and miR-7974-treated samples were statistically significant. …”

Data Sheet 1_CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis.docx by Ping Zhao (47228)

Data Sheet 1_The efficacy and safety of panax quinquefolius saponin for heart failure: a systematic review and meta-analysis.pdf by Jing Wang (6206297)

Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture by Paul Yancey (14354982)

“…Our methods of capture (nets and uninsulated baited traps with rapid ascent into warmer temperatures and decreasing pressure) apparently do not allow fish to regulate TMAO before their metabolisms shut down, but down-regulation might occur with a gentler retrieval method, e.g., slower and/or insulated from temperature changes. …”

Table 1_COVID-19 pandemic increased ESKAPEEc bloodstream infections and amplified carbapenem resistance in Chinese children: a multicenter surveillance study (2016–2023).xls by Xiaoqiang Li (612879)

“…Between 2016–2019 and 2020–2023, resistance to ceftazidime and gentamicin decreased in Escherichia coli and Klebsiella pneumoniae while resistance to imipenem and meropenem increased. …”

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” by Chanping You (9067448)

“…The androgen receptor (AR), a widely expressed hormonal receptor in breast cancer, has an unclear role in disease progression. Emerging evidence suggests AR may contribute to drug resistance in various cancers, including breast cancer; however, the underlying mechanisms remain underexplored.…”

Table 2_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine... by Qi Sun (127)

“…Furthermore, IP ameliorated the cartilage extracellular matrix degradation, significantly increased Aggrecan and Col II expression and decreased the expression of MMP13 and ADAMTS-4. …”

Table 1_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine... by Qi Sun (127)

“…Furthermore, IP ameliorated the cartilage extracellular matrix degradation, significantly increased Aggrecan and Col II expression and decreased the expression of MMP13 and ADAMTS-4. …”

Data collected from pregnant women for the analysis of placental anemia, placental malaria, Cytokines and birth anthropometric indices by Bamgboye Morakinyo Afolabi (16838970)

“…Pathologies associated with PM seems to be the effect of a change in immune status from antibody-mediated immune response to cell-mediated immune response resulting into excess inflammation, oxidative stress, apoptosis, and decreased heat shock protein expression [4]. …”

Figure 2 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma by Gwendolyn M. Cramer (16964052)

“…<b>B,</b> The addition of αPD-1 (TC/αPD-1, dotted black line) to TC did not significantly change tumor response (<i>P</i> = 0.27). …”

DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx by Mehri Hajiaghayi (19822665)

“…</p>Results<p>Nebivolol treatment decreased IL-17A and IFN-γ secretion by activated memory Th cells and elevated IL-4 levels. …”

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity by Mengyu Liu (2890397)

“…Further analysis indicated significant impairment of autophagic flux by TMT via suppressed lysosomal function, such as by inhibiting lysosomal proteolysis and changing the lysosomal pH, thereby contributing to defects in autophagic clearance and subsequently leading to nerve cell death. …”

Supplementary Material for: Camrelizumab combined with Lenvatinib and RALOX-HAIC for unresectable hepatocellular carcinoma (Cal Era): a prospective, single-arm, phase II trial by figshare admin karger (2628495)

“…Serum IL2, CXCL13, and CCL19 levels significantly differed between stable disease and partial response patients (P < 0.05 and |fold change| > 1.5). …”

HK2 regulates mRNA translation in melanoma cells. by Ana Luisa Dian (22258504)

“…HK2 depletion significantly decreased the abundance of <i>SOX10</i>, <i>CDH2</i>, and <i>WNT5A</i> mRNAs extracted from polysome fractions, but not in total RNAs. …”