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significant change » significant changes (Expand Search), significant challenge (Expand Search), significant challenges (Expand Search)
changes decrease » larger decrease (Expand Search), change increases (Expand Search)
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6561
Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg
Published 2024“…Background<p>The pivotal responsibility of GABAergic interneurons is inhibitory neurotransmission; in this way, their significance lies in regulating the maintenance of excitation/inhibition (E/I) balance in cortical circuits. …”
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6562
Interim Effects of Zoledronate, Denosumab, or Teriparatide on Bone Microarchitecture in Type 2 Diabetes: A Pilot Trial
Published 2025“…</p><p dir="ltr">Main Outcome Measure: Pre-specified 24-week interim exploratory analysis focusing on changes in bone microarchitecture assessed by second-generation HR-pQCT at distal tibia and radius. …”
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6563
DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx
Published 2024“…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …”
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6564
Data Sheet 1_Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats.docx
Published 2025“…Gut microbiota associated with SBAs metabolism were significantly reduced, leading to decreased intestinal deoxycholic acid (DCA) and lithocholic acid (LCA). …”
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6565
This is raw data of IL-1β ELISA.
Published 2025“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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6566
This is raw data of IL-10 real-time PCR.
Published 2025“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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6567
This is raw data of Gal-9 real-time PCR.
Published 2025“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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6568
This is raw data of IL-10 ELISA.
Published 2025“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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6569
This is raw data of NF-κB real-time PCR.
Published 2025“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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6570
This is raw data of IL-1β real-time PCR.
Published 2025“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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6571
This is raw data of β-catenin real-time PCR.
Published 2025“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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6572
Details of the primers applied in real-time PCR.
Published 2025“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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6573
This is raw data of viability data.
Published 2025“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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6574
H2AK119ub is neurodevelopmentally enriched within H3K9ac-positive euchromatin.
Published 2025“…(F) Heatmaps depicting H3K9ac CUT&RUN data within loci with no change, increased or decreased H2AK119ub over neurodevelopment. …”
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6575
DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx
Published 2024“…</p>Results<p>Nebivolol treatment decreased IL-17A and IFN-γ secretion by activated memory Th cells and elevated IL-4 levels. …”
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6576
KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity
Published 2024“…Further analysis indicated significant impairment of autophagic flux by TMT via suppressed lysosomal function, such as by inhibiting lysosomal proteolysis and changing the lysosomal pH, thereby contributing to defects in autophagic clearance and subsequently leading to nerve cell death. …”
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6577
Minimum data set used in the article.
Published 2025“…<div><p>The dynamics and balance of soil carbon, nitrogen, and phosphorus significantly affect soil microbial activity and plants’ nutrient absorption and utilization. …”
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6578
Data Sheet 1_Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.pdf
Published 2024“…</p>Results<p>VWF, VCAM-1, and ROS expression was significantly higher in cells exposed to PE sera vs. control (12.3 ± 8.1, 3.6 ± 2.3, and 1.8 ± 0.2, respectively, p < 0.05), though significantly lower in cells exposed to depleted PE (dPE) sera (6.1 ± 2.7, 0.7 ± 0.6, and 1.2 ± 0.1, respectively, vs. control, p < 0.05). …”
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6579
The role of Cathepsin inhibitors in RGC damage in hypoxic retina.
Published 2025“…Treatment with neither Odanacatib nor SID26681509 reduced the percentage of PI-positive RGCs, whereas the positive control SNJ-1945 significantly decreased the percentage. Data are means ± SD (n = 3). …”
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6580
Table 1_Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice.xlsx
Published 2025“…Single-cell sequencing was employed to explore changes in the colonic immune microenvironment and cellular signaling pathways after Resveratrol treatment. …”