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6621
Figure 1 from Tumor-Immune Signatures of Treatment Resistance to Brentuximab Vedotin with Ipilimumab and/or Nivolumab in Hodgkin Lymphoma
Published 2025“…The −log<sub>10</sub> (<i>P</i> value) is represented by the size of the circles, indicating statistical significance as the circles increase. <b>D,</b> Line and boxplot figures showing the changes in expression for markers increased posttreatment such as PDCD1, GMZA, PTN, CAIX, IL18, CD28, and markers decreased posttreatment such as CCL17, ANGPT2, IL13, and CXCL13. …”
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6622
Data Sheet 1_Dynamics and drivers of the carbonate system: response to terrestrial runoff and upwelling along the Northeastern Colombian Caribbean coast.pdf
Published 2025“…</p>Results<p>The results showed significant seasonal variability influenced by annual changes in coastal upwelling, rainfall, and river runoff. …”
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6623
Table 1_Mitochondrial oxygen metabolism as a potential predictor of weight loss after laparoscopic sleeve gastrectomy for class III obesity.xlsx
Published 2025“…They showed a significant weight loss and a decrease in relative fat mass after six months. …”
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6624
Urbanization and climate jointly shape the composition of plant life forms
Published 2024“…The compositions of plant life forms were significantly controlled by urbanization intensity and annual mean temperature. …”
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6625
Image2_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.tif
Published 2024“…</p>Results<p>Following CTD exposure, the mouse liver showed significant pathological damage and an increase in autophagic lysosomes, while the vitality of L-O2 cells showed a significant decrease. …”
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6626
Table1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.pdf
Published 2024“…</p>Results<p>Following CTD exposure, the mouse liver showed significant pathological damage and an increase in autophagic lysosomes, while the vitality of L-O2 cells showed a significant decrease. …”
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6627
Image1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.png
Published 2024“…</p>Results<p>Following CTD exposure, the mouse liver showed significant pathological damage and an increase in autophagic lysosomes, while the vitality of L-O2 cells showed a significant decrease. …”
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6628
Supplementary file 1_HuangLian-4 alleviates myocardial ischemia-reperfusion injury by activating the pro-survival STAT3 signaling pathway.doc
Published 2025“…This activation of STAT3 was accompanied by a significant increase in the anti-apoptotic protein Bcl-2 and a decrease in pro-apoptotic Bax, alongside the suppression of the maladaptive factor HIF-1α. …”
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6629
Table 5_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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6630
Table 1_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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6631
Table 2_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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6632
Table 4_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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6633
Table 3_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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6634
Table 6_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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6635
Table 3_Ageing, clinical complexity, and exercise therapy: a multidimensional approach.docx
Published 2025“…Ageing represents the primary risk factor for chronic degenerative diseases, especially involving cardiovascular, metabolic, respiratory, and osteoarticular systems, determining the decrease in activities and quality of daily life. …”
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6636
Table 1_Ageing, clinical complexity, and exercise therapy: a multidimensional approach.docx
Published 2025“…Ageing represents the primary risk factor for chronic degenerative diseases, especially involving cardiovascular, metabolic, respiratory, and osteoarticular systems, determining the decrease in activities and quality of daily life. …”
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6637
Table 2_Ageing, clinical complexity, and exercise therapy: a multidimensional approach.docx
Published 2025“…Ageing represents the primary risk factor for chronic degenerative diseases, especially involving cardiovascular, metabolic, respiratory, and osteoarticular systems, determining the decrease in activities and quality of daily life. …”
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6638
Data Sheet 1_Understanding mechanistic relationships between IgG titers and Fc effector functions: a computational framework to assess polyfunctionality.docx
Published 2025“…Surprisingly, simulated boosting of IgG3 alone had the potential to significantly decrease ADCP (p<0.00001), though it would increase ADCC responses. …”
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6639
Liquid mosquito repellent induces toxic effects in zebrafish
Published 2024“…Analysis of gene expression demonstrated significant dysregulation in genes associated with oxidative stress (SOD1, CAT), inflammatory markers (TNF-α, IL-1β), apoptotic regulators (p53, bcl2), and neurobiological genes (brain-derived neurotrophic factor, bdnf). …”
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6640
Table 1_Enhancement of prefrontal functional connectivity under the influence of concurrent physical load during mental tasks.docx
Published 2024“…</p>Results<p>On the basis of effects of cognitive tasks, the concurrent physical activities would further increase National Aeronautics and Space Administration Task Load Index score (p < 0.05) and decrease task performance (p < 0.05). The fNIRS-based results showed that cognitive and physical loads had significant interaction effects on CORR (p < 0.05), COH (p < 0.05), and PLV (p = 0.010), while their main effects were not significant. …”