Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts by Yu-Tse Lee (19944891)

“…In vitro assays, including wound-healing, Boyden chamber, tube-formation, and real-time cell analyses, showed that MSN-PEG/TA 25 could modulate cell migration of 4T1 breast cancer cells and interrupt tube formation by human umbilical vein endothelial cells (HUVECs), key factors in suppressing cancer metastasis. The synergistic effect of MSN-PEG/TA 25 combined with liposomal-encapsulated doxorubicin (Lipo-Dox) significantly boosted mouse survival rates, outperforming Lipo-Dox monotherapy. …”

Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts by Yu-Tse Lee (19944891)

“…In vitro assays, including wound-healing, Boyden chamber, tube-formation, and real-time cell analyses, showed that MSN-PEG/TA 25 could modulate cell migration of 4T1 breast cancer cells and interrupt tube formation by human umbilical vein endothelial cells (HUVECs), key factors in suppressing cancer metastasis. The synergistic effect of MSN-PEG/TA 25 combined with liposomal-encapsulated doxorubicin (Lipo-Dox) significantly boosted mouse survival rates, outperforming Lipo-Dox monotherapy. …”

Data Sheet 1_Metastatic organ count stratifies survival in immunotherapy-treated metastatic colorectal cancer: a retrospective cohort study.docx by Hai-Yan Fu (1586935)

“…</p>Results<p>Patients with varying metastatic organ counts exhibited significantly different objective response rates (ORRs) (1 to ≥4 organs: 49.3%, 30.0%, 19.6%, 5.9%, respectively, P < 0.001). …”

Table 1_Association between body composition in early pregnancy and the risk of gestational diabetes mellitus.docx by Yan Li (23143)

“…Background<p>Gestational diabetes mellitus (GDM) is a common complication during pregnancy that poses serious health risks to both mothers and their offspring. Risk factors for GDM, such as obesity, have been extensively reported. …”

Data Sheet 1_Development of a rapid fiber-detection system using artificial intelligence in phase-contrast microscope images of actual atmospheric samples.pdf by Yukiko Iida (21596408)

“…Additionally, since the counting process relies on visual fiber counting, analytical accuracy can be decreased due to factors such as analyst fatigue. Ambient air samples or air samples collected near demolition sites were observed and acquired using a phase contrast microscope. …”

Long-term prognostic value of thyroid hormone levels in chronic critical illness patients by Zhaoxiang Li (11277207)

“…Lower free triiodothyronine (FT3) levels (<1.19 pmol/L) or reduced free thyroxine (FT₄) levels (<9.655 pmol/L) were significantly associated with reduced survival in CCI patients with NTIS. …”

Table 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.xlsx by Yan Li (23143)

“…Furthermore, intermediate or healthy lifestyles significantly decreased the age-related risk of stroke, chronic liver disease, chronic kidney disease (CKD), osteoporosis, osteoarthritis, and hypertension. …”

Supplementary file 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.docx by Yan Li (23143)

“…Furthermore, intermediate or healthy lifestyles significantly decreased the age-related risk of stroke, chronic liver disease, chronic kidney disease (CKD), osteoporosis, osteoarthritis, and hypertension. …”

Data Sheet 1_Fast perceptual learning induces location-specific facilitation and suppression at early stages of visual cortical processing.docx by Yajie Wang (184298)

“…<p>Tens of minutes of training can significantly improve visual discriminability of human adults, and this fast perceptual learning (PL) effect is usually specific to the trained location, with little transfer to untrained locations. …”

Image 2_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif by Kai Liu (159026)

“…We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …”

Image 3_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif by Kai Liu (159026)

“…We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …”

Table1_SMAD4 enhances the cytotoxic efficacy of human NK cells against colorectal cancer cells via the m6A reader YTHDF2.docx by Xinxin Li (281237)

“…</p>Results<p>Our findings revealed that the expression of SMAD4 is decreased in NK cells within the TME of human CRC. …”

Image 1_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif by Kai Liu (159026)

“…We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …”

H2AK119ub is neurodevelopmentally enriched within H3K9ac-positive euchromatin. by Aditya Parmar (22331873)

“…(F) Heatmaps depicting H3K9ac CUT&RUN data within loci with no change, increased or decreased H2AK119ub over neurodevelopment. …”

Data Sheet 1_Global burden of nasopharyngeal carcinoma attributable to alcohol use: a 1990–2021 analysis with projections to 2040.pdf by Zhenyi Lu (22004786)

“…Trends were quantified by average annual percentage change (AAPC) and projections were generated using Bayesian age–period–cohort models.…”

Data Sheet 2_Global burden of nasopharyngeal carcinoma attributable to alcohol use: a 1990–2021 analysis with projections to 2040.zip by Zhenyi Lu (22004786)

“…Trends were quantified by average annual percentage change (AAPC) and projections were generated using Bayesian age–period–cohort models.…”

Data Sheet 1_A novel short-course, low-intensity blood-flow-restricted exercise (BFRE) regimen to study satellite cell function in critical illness survivors with sustained muscle... by Sunita Mathur (759075)

“…In controls, satellite cell content and MuRF1 transcript expression were significantly higher (1.53 ± 0.30- and 1.34 ± 0.31-fold difference, respectively) and myostatin transcript expression was significantly lower (0.58 ± 0.31-fold difference) in BFRE-trained versus untrained VL. …”

Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat synd... by Yun Yang (417125)

“…Complete blood count (CBC), blood biochemistry, short-chain fatty acids (SCFAs), gut microbiota composition in the colon, and metabolites in the cecum were analyzed.</p> <p>DYY significantly reduced symptom scores and decreased CRP level, while also regulating parameters in CBC and biochemical profiles. …”

Table1_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg by Yun Zhou (308977)

“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”

Table 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx by Jingjing Chen (293564)

“…Regulatory network reconstruction identified 32 transcription factors, 24 RNA-binding proteins, and 62 miRNAs as putative upstream regulators of key genes. …”