Cox proportional hazard ratios. by Bryan S. Margulies (21492667)

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Liver samples were stained with hematoxylin and eosin and imaged at 4x. by Bryan S. Margulies (21492667)

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Bioluminescent Doubling Time. by Bryan S. Margulies (21492667)

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Study Design. by Bryan S. Margulies (21492667)

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Liver weights were normalized by the mouse body weight to derive the %liver weight. by Bryan S. Margulies (21492667)

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Histomorphometric analysis of the tumor volume fraction (V_f) in the liver and necrosis volume fraction. by Bryan S. Margulies (21492667)

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(A) Release rate (i.e., elution) of N-allyl noroxymorphone hydrochloride evaluated using UPLC from two samples of MBC-005. The equations predict that at 24-hours there will be betw... by Bryan S. Margulies (21492667)

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The MTT assay and the LDH assay were used to assess the effects of the hydrogel component of MBC-005 on tumor cell number and cell death. by Bryan S. Margulies (21492667)

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The spheroid assay is used to assess long-term effects of therapy on tumor cell by culturing the tumor cells in a micro-mass, which is a 3D tumor mass used as a surrogate for in vi... by Bryan S. Margulies (21492667)

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Survival in mice with liver metastases after MBC-005 TREATMENT. by Bryan S. Margulies (21492667)

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Inhibitor versus the normalized dose response curves. by Bryan S. Margulies (21492667)

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Viscosity assessed using a tuning-fork viscometer. by Bryan S. Margulies (21492667)

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Interpolated survival in mice with or without lung metastases. by Bryan S. Margulies (21492667)

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The p21 ELISA assay was used to assess the effects of MBC-005 on tumor cell expression of p21. by Bryan S. Margulies (21492667)

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GRADE judgements. by Da Huang (1306407)

“…Furthermore, there was no significant difference in the change in resting heart rate (RHR) (MD = 2.04, 95% CI: −2.71–6.78; P = 0.40) between the physical activity group and the control group, but there was a significant difference in the change in maximum heart rate (HR-max) (MD = 6.27, 95% CI: 1.75–10.97, P = 0.007). …”

Basic characteristics of the included studies. by Da Huang (1306407)

“…Furthermore, there was no significant difference in the change in resting heart rate (RHR) (MD = 2.04, 95% CI: −2.71–6.78; P = 0.40) between the physical activity group and the control group, but there was a significant difference in the change in maximum heart rate (HR-max) (MD = 6.27, 95% CI: 1.75–10.97, P = 0.007). …”

The data of meta-analysis. by Da Huang (1306407)

“…Furthermore, there was no significant difference in the change in resting heart rate (RHR) (MD = 2.04, 95% CI: −2.71–6.78; P = 0.40) between the physical activity group and the control group, but there was a significant difference in the change in maximum heart rate (HR-max) (MD = 6.27, 95% CI: 1.75–10.97, P = 0.007). …”

Risk of bias. by Da Huang (1306407)

“…Furthermore, there was no significant difference in the change in resting heart rate (RHR) (MD = 2.04, 95% CI: −2.71–6.78; P = 0.40) between the physical activity group and the control group, but there was a significant difference in the change in maximum heart rate (HR-max) (MD = 6.27, 95% CI: 1.75–10.97, P = 0.007). …”

Overall risk of bias assessment. by Da Huang (1306407)

“…Furthermore, there was no significant difference in the change in resting heart rate (RHR) (MD = 2.04, 95% CI: −2.71–6.78; P = 0.40) between the physical activity group and the control group, but there was a significant difference in the change in maximum heart rate (HR-max) (MD = 6.27, 95% CI: 1.75–10.97, P = 0.007). …”

Funnel plot of VO_2Peak inclusion studies. by Da Huang (1306407)

“…Furthermore, there was no significant difference in the change in resting heart rate (RHR) (MD = 2.04, 95% CI: −2.71–6.78; P = 0.40) between the physical activity group and the control group, but there was a significant difference in the change in maximum heart rate (HR-max) (MD = 6.27, 95% CI: 1.75–10.97, P = 0.007). …”