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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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142
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…<p dir="ltr">Nanoparticles (NP) have gained significant attention in biomedical research due to their unique properties and potential applications in drug delivery, imaging, and diagnostics. …”
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143
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …”
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144
Symptoms of depression and anxiety in anorexia nervosa
Published 2014“…The relationship between these clinical manifestations and the biological changes caused by starvation is not well understood. …”
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145
Proteome analysis of Candida albicans cell wall mutants. (c2011)
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146
In vivo assessment of the nephrotoxic effects of the synthetic cannabinoid AB-FUBINACA
Published 2024“…</p><h3>Conclusion</h3><p dir="ltr">These results indicate that AB-FUBINACA can trigger oxidative stress and inflammation, and activate caspase-dependent apoptosis in the kidney, with these processes being possibly linked to disruption of mitochondrial complexes and could be an underlying mechanism of SCs-induced nephrotoxicity.</p><h2>Other Information</h2><p dir="ltr">Published in: Forensic Toxicology<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11419-024-00699-9" target="_blank">https://dx.doi.org/10.1007/s11419-024-00699-9</a></p>…”
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Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy
Published 2020“…The majority of induced T cells displayed an effector memory phenotype. …”
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148
Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
Published 2017“…These findings have significant policy implications for the provision of guidance to policymakers in identifying optimal energy mixes and in pursuing realistic goals to enhance renewable energy penetration and to contribute to the current efforts of tackling climate change.…”
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149
Competition vs cooperation: An agent based model for sustainable tomatoes’ import system
Published 2024“…Based on the research findings, a competitive global market can bring economic benefits to Qatar as an importing nation, but this approach also entails substantial <u>water consumption</u> and results in significant environmental emissions. Conversely, collaboration among exporting countries demonstrates a potential 20% reduction in water usage and a 15% decrease in environmental emissions compared to the competitive scenario, offering enhanced environmental performance albeit at<u> higher economic costs</u>. …”
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150
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Published 2015“…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …”
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151
The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
Published 2018“…It may assist policymakers of the Dubai government to develop and implement systematic changes into the current risk management processes. …”
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152
Mechanisms and evidence of chloride-accelerated pitting in gas pipeline steel
Published 2025“…The detection of chlorine-induced compounds such as akaganeite (β-FeOOH), supports the theory of chloride-induced passivity failure and localised acidification. …”
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153
Causes of Delay in Construction Projects in Oil and Gas Construction Industry
Published 2017“…With regard to design, the contractor’s need to decrease construction costs through a cheaper design was found to be a factor in design changes. …”
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154
The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France
Published 2018“…Accordingly, we find that, following IFRS adoption, earnings management activities decrease among high-divergence firms prior to issuing SEOs. …”
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Coevolving residues distant from the ligand binding site are involved in GAF domain function
Published 2025“…Mutational incorporation into a Bioluminescence Resonance Energy Transfer (BRET)-based biosensors, which detects ligand-induced conformational changes, showed altered GAF domain conformation and increased EC50 for cGMP-induced conformational changes. …”
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157
Numerical simulations on thermomechanical performance of 3D printed chopped carbon fiber‐reinforced polyamide‐6 composites: Effect of infill design
Published 2023“…In addition, the mechanical testing simulations were performed on the specimens with 3DP process-induced defects obtained from the process simulation results. …”
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158
DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression
Published 2015“…In summary, our results shed the light on the possible role of DNAJB3 in improving insulin sensitivity and glucose uptake through JNK repression and suggest that DNAJB3 could be a potential target for therapeutic treatment of obesity-induced insulin resistance.</p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/srep14448" target="_blank">https://dx.doi.org/10.1038/srep14448</a></p>…”
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Antibacterial Properties of Polysulfone Membranes Blended with Arabic Gum
Published 2019“…These changes were due to the amphiphilic properties of AG macromolecules that contained negatively charged hydrophilic residues. …”
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Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
Published 2024“…<h3>Key Clinical Message</h3><p dir="ltr">This report documents the treatment of a 41‐year‐old male with sickle cell disease (SCD) and repeated stuttering priapism using crizanlizumab, which alleviated the priapism but induced a significant vaso‐occlusive crisis during the second infusion. …”