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significant linear » significant clinical (Expand Search), significant gender (Expand Search), significant level (Expand Search)
changes decrease » larger decrease (Expand Search), change increases (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
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7101
Soluble average Klotho level as a prognostic marker for acute kidney injury outcomes: a 90-day follow-up study
Published 2025“…Interestingly, we found that sKlotho value was significantly decreased and an alteration in the sKlotho level ran parallel to changes in kidney function in AKI patients. …”
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7102
The role of Cathepsin inhibitors in RGC damage in hypoxic retina.
Published 2025“…Treatment with neither Odanacatib nor SID26681509 reduced the percentage of PI-positive RGCs, whereas the positive control SNJ-1945 significantly decreased the percentage. Data are means ± SD (n = 3). …”
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7103
Table 1_Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice.xlsx
Published 2025“…Single-cell sequencing revealed that Resveratrol primarily targeted colonocytes, decreasing genes related to apoptosis and the P53 pathway. …”
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7104
Table 1_Shengxue Busui Decoction activates the PI3K/Akt and VEGF pathways, enhancing vascular function and inhibiting osteocyte apoptosis to combat steroid-induced femoral head nec...
Published 2025“…In vivo, SBD intervention significantly reduced bone structural damage and apoptosis, decreasing the rate of empty bone lacunae. …”
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7105
Impact of Pilates training on gait performance in individuals with unilateral transtibial amputation
Published 2025“…The intact side also showed increased step length (<i>p</i> = 0.009), while stance time (<i>p</i> = 0.011) and swing time (<i>p</i> = 0.005) decreased post-training. No changes in asymmetry were observed, regardless of walking speed (<i>p</i> > 0.05). …”
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7106
Table 1_Silicon application enhances drought resilience in buckwheat: a comparative study of three varieties.docx
Published 2025“…La Harpe had the highest MDA accumulation in roots, increased 5mC levels in leaves, and was the only line with decreased water use efficiency (WUE). Smuga exhibited the highest natural proline level and the strongest proline increase under drought. …”
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7107
Table 1_Pingwei Powder alleviates high-fat diet-induced colonic inflammation by modulating microbial metabolites SCFAs.xlsx
Published 2025“…Experimental validation showed that PWP significantly downregulated the levels of PI3K, pAKT/AKT, and pmTOR/mTOR in colonic tissue, thereby enhancing autophagy in colonic epithelial cells, as evidenced by decreased levels of P62 and increased LC3B-II/LC3B-I ratios. …”
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7108
Table 1_The global, regional, and national burden of pediatric stone disease: 1990–2021 and projections for the next two decades.docx
Published 2025“…Background<p>Pediatric stone disease, once considered rare, has gained significant attention over the past decade owing to its rapidly increasing incidence. …”
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7109
Data Sheet 1_Global, regional, and national burden of sudden infant death syndrome, 1990–2021: a comprehensive analysis of GBD 2021 data with insights into the impact during the CO...
Published 2025“…This study investigates whether the global SIDS burden has changed, particularly during the COVID-19 pandemic.…”
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7110
Lingganwuweijiangxin Decoction suppresses allergic airway inflammation in Guinea pigs with cough variant asthma by regulating the treg/Th17 balance and the JAK1/STAT6 signaling pat...
Published 2025“…</p> <p>Compared to the control group, the model group showed significantly more coughs, which were markedly reduced by LD treatment (<i>p</i> = 0.0083 and <i>p</i> = 0.0117). …”
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7111
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7112
Minimum data set used in the article.
Published 2025“…<div><p>The dynamics and balance of soil carbon, nitrogen, and phosphorus significantly affect soil microbial activity and plants’ nutrient absorption and utilization. …”
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7113
Data Sheet 1_Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.pdf
Published 2024“…</p>Results<p>VWF, VCAM-1, and ROS expression was significantly higher in cells exposed to PE sera vs. control (12.3 ± 8.1, 3.6 ± 2.3, and 1.8 ± 0.2, respectively, p < 0.05), though significantly lower in cells exposed to depleted PE (dPE) sera (6.1 ± 2.7, 0.7 ± 0.6, and 1.2 ± 0.1, respectively, vs. control, p < 0.05). …”
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7114
Chronic hyperpolarization of dFB<sup>23E10</sup>Ո<sup>84C10</sup> neurons promotes sleep and impairs sleep homeostasis.
Published 2025“…Two-tailed Mann–Whitney U tests revealed that sleep rebound is significantly decreased at all time points between controls and <i>dFB-Split>UAS-Kir2.1</i> female flies. …”
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7115
30-year trends in incidence of acute STEMI and NSTEMI in the Belgian Province of Luxembourg. A long-term follow-up of the MONICA-BELLUX registry
Published 2025“…</p><p>b) What this study adds</p><p>In a 30-year registry in Luxembourg using modern AMI definitions, overall, AMI incidence decreased significantly, primarily due to a 3.8-fold reduction in STEMI.…”
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7116
Table_1_Engaging Underserved Communities in COVID-19 Health Equity Implementation Research: An Analysis of Community Engagement Resource Needs and Costs.docx
Published 2025“…</p>Conclusions<p>Study findings indicate that the most significant investment of resources is required in the startup period. …”
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7117
Table 5_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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7118
Table 4_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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7119
Table 2_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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7120
Supplementary Material for: Trends and Impact of Early Medical Complications in Acute Ischemic Stroke: Data from the Austrian Stroke Unit Registry
Published 2025“…The effect sizes didn’t change significantly through the observed years. Conclusions This study observed a significant reduction in the prevalence of early medical complications after acute ischemic stroke. …”