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Showing 101 - 120 results of 291 for search '(( significant ((changes decrease) OR (largest decrease)) ) OR ( significant potential agent ))', query time: 0.10s Refine Results
  1. 101

    Anticancer Effects of Lebanese Cannabis Oil Against in vivo and in vitro Models of Squamous Cell Carcinoma by Azar Atallah, Shirine

    Published 2023
    “…Cannabis sativa L. has a long history of use in traditional medicine for various ailments as an analgesic, anticonvulsant, hypnotic, tranquilizer, and anti-inflammatory agent. Emerging evidence in preclinical studies has also demonstrated the anticancer effect of cannabinoids, which are the major components of the plant. …”
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    masterThesis
  2. 102

    Drug-free phototherapy of superficial tumors by Mehanna, Stephanie

    Published 2021
    “…When tested on a DMBA/TPA skin carcinogenesis model, a 90-min exposure to white light thrice weekly resulted in a significant decrease in tumor volumes/incidence compared to control and cisplatin groups, and restored normal morphological features, as confirmed by histopathology. …”
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  3. 103

    Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic by Turki, O.

    Published 2023
    “…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. …”
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  4. 104

    A clustering metaheuristic for large orienteering problems by Almiqdad Elzein (13141038)

    Published 2022
    “…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
  5. 105

    The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models by Al Toufaily, Sahar

    Published 2021
    “…The major component of DCOE, β-2-himachalen-6-ol (HC), has been isolated and found to be a potential safe and potent chemotherapeutic agent. Additional recent studies showed that Cannabis sativa oil extract (COE) demonstrated potent anti-inflammatory effects. …”
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    masterThesis
  6. 106

    Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels by Haya Al-Sulaiti (5449256)

    Published 2024
    “…<p dir="ltr">Nanoparticles (NP) have gained significant attention in biomedical research due to their unique properties and potential applications in drug delivery, imaging, and diagnostics. …”
  7. 107

    Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

    Published 2020
    “…Finally, only in lower sumac dose, significant decreases in methylation status of three out of five gene promoters–ATM, PTEN, and TIMP3 (PITX2 and RASSF1 promoters were not changed). …”
  8. 108

    Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

    Published 2016
    “…Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …”
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    article
  9. 109

    Simulating and comparing various price-driven bid selection methods from an owner's perspective. (c2017) by Ammoury, Michael Fayez

    Published 2017
    “…Although the latter method ensures transparency in the selection process through considering only one objective criterion which is the bid price, it often leads to adversarial relationships, less cooperation among different parties involved in the project, and potential compromise on the project quality. Furthermore, it is often accompanied with a significant number of claims and disputes that often result in cost overruns and schedule delays. …”
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    masterThesis
  10. 110

    Fermentation-induced modifications to the structural, surface, and functional properties of quinoa proteins by Mohammad Alrosan (20089263)

    Published 2025
    “…Using advanced analytical techniques, such as ultraviolet, fluorescence, and FT-IR spectra, it has been demonstrated that fermented QPs exhibit significant structural changes (P < 0.05) compared to unfermented QPs. …”
  11. 111

    Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma by Abou-Ghazal, Mohamed

    Published 2008
    “…We have designed and synthesized a series of potential inhibitors of the JAK2/STAT3 pathway and identified a lead compound displaying high activity within in vivo models. …”
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  12. 112

    Symptoms of depression and anxiety in anorexia nervosa by Mattar, Lama

    Published 2014
    “…The relationship between these clinical manifestations and the biological changes caused by starvation is not well understood. …”
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  13. 113

    Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia by Shilpa Kuttikrishnan (3520079)

    Published 2019
    “…Our interesting findings raise the possibility of considering curcumin as a potential therapeutic agent for the treatment of B-Pre-ALL.…”
  14. 114
  15. 115

    Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials by Pieter Francsois, Fouche

    Published 2024
    “…Study objectiveTraumatic injury causes a significant number of deaths due to bleeding. Tranexamic acid (TXA), an antifibrinolytic agent, can reduce bleeding in traumatic injuries and potentially enhance outcomes. …”
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  16. 116

    Refractory cold agglutinin disease successfully treated with daratumumab. A case report and review of literature by Abdelaziz Mohamed (14777668)

    Published 2023
    “…</p><h3>Conclusion</h3><p dir="ltr">Our case is the third reported case of refractory CAD successfully treated with daratumumab, which suggests that daratumumab might be a potential agent for the treatment and control of refractory Cold Agglutinin Disease.…”
  17. 117

    Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data by Squalli, Jay

    Published 2017
    “…These findings have significant policy implications for the provision of guidance to policymakers in identifying optimal energy mixes and in pursuing realistic goals to enhance renewable energy penetration and to contribute to the current efforts of tackling climate change.…”
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  18. 118

    Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice by Julie Decock (44558)

    Published 2015
    “…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …”
  19. 119

    The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function by MUBARAK, ALIA MARJAN

    Published 2018
    “…It may assist policymakers of the Dubai government to develop and implement systematic changes into the current risk management processes. …”
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  20. 120

    The effect of colchicine on myocardial infarction: An updated systematic review and meta-analysis of randomized controlled trials by Ayesha, Younas

    Published 2024
    “…Colchicine, an anti-inflammatory agent, exhibits potential benefits in various cardiovascular conditions such as coronary artery disease, pericarditis and atrial fibrillation. …”
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    article