يعرض 7,481 - 7,500 نتائج من 8,106 نتيجة بحث عن '(( significant ((changes decrease) OR (largest decrease)) ) OR ( significant progress decrease ))', وقت الاستعلام: 0.49s تنقيح النتائج
  1. 7481

    Data Sheet 1_Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and... حسب Dilpreet Kour (10872766)

    منشور في 2025
    "…Background and Aim<p>Alzheimer’s disease (AD) progresses with Aβ plaque deposition and neuroinflammation. …"
  2. 7482

    Data Sheet 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.pdf حسب Shuangmei Zhang (1807303)

    منشور في 2025
    "…Th17 cell frequency and IL-17 levels decreased by 68 and 84.47%, respectively. Strong baseline correlations were observed between IL-17, Th17, and clinical scores (r = 0.642–0.970, p < 0.001), with progressive uncoupling of these relationships during treatment. …"
  3. 7483

    Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx حسب Jian-Tong (21583487)

    منشور في 2025
    "…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …"
  4. 7484

    Data Sheet 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx حسب Lili Zhou (265076)

    منشور في 2025
    "…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …"
  5. 7485

    Presentation_1_Multifaceted neuroprotective approach of Trolox in Alzheimer's disease mouse model: targeting Aβ pathology, neuroinflammation, oxidative stress, and synaptic dysfunc... حسب Muhammad Tahir (741682)

    منشور في 2024
    "…<p>Alzheimer's disease (AD) is a progressive neurodegenerative disorder pathologically characterized by the deposition of amyloid beta (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain. …"
  6. 7486

    Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx حسب Fei Yan (128878)

    منشور في 2025
    "…The outcomes included real-world progression-free survival (rwPFS), objective response rate (ORR), disease control rate (DCR), overall survival (OS) and safety.…"
  7. 7487

    Characteristics of children in the study. حسب Shijie Yu (511369)

    منشور في 2025
    "…The self-evaluation of eye health was positively associated with both UI values and VAS scores. Furthermore, decreases in UI values and VAS scores were associated to the onset of myopia, and were more pronounced in children with myopia progression.…"
  8. 7488

    Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i> حسب Meng-Ru Guo (21375491)

    منشور في 2025
    "…Longitudinal tracking of fungal infection progression illustrated that mice lungs infected with <i>rnh2B</i>Δ mutants maintained a low yet stable fungal burden, in contrast to a significant reduction in fungal load observed in conjunction with <i>RNH2B</i> overexpression, ultimately leading to complete clearance. …"
  9. 7489

    Neurochemical identity of dFB<sup>23E10</sup>Ո<sup>84C10</sup> neurons. حسب Joseph D. Jones (13883524)

    منشور في 2025
    "…A Kruskal–Wallis ANOVA followed by Dunn’s multiple comparisons revealed that acutely silencing VGlut-AD; 84C10-DBD and 84C10-AD; ChAT-DBD neurons significantly decreases sleep. ****<i>P</i> < 0.0001. …"
  10. 7490
  11. 7491
  12. 7492
  13. 7493

    Table 1_Digital health management models improve the metabolism, sleep, and gut microbiota in patients with metabolic disorders.docx حسب Jie Zhang (64655)

    منشور في 2025
    "…All outcomes in the DHM group were significantly superior to those in the control group (all p < 0.05).…"
  14. 7494
  15. 7495

    Data Sheet 1_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf حسب Ditte Ljungquist (20446670)

    منشور في 2024
    "…The yearly level of antibiotic use in CGE declined from 8.1% in 2020 to 3.9% in 2023, with a statistically significant annual percentage change (APC) of −21.3% (95% CI, −22.8 to −19.7). …"
  16. 7496
  17. 7497

    Table 1_Effect of cholecalciferol on immune and vascular function in non-diabetic chronic kidney disease.docx حسب Kajal Kamboj (12769602)

    منشور في 2025
    "…A significant increase in mRNA expression of vitamin D-responsive genes (cathelicidin, IL-10, VDR, and CYP27B1) was observed. …"
  18. 7498

    Data Sheet 3_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf حسب Ditte Ljungquist (20446670)

    منشور في 2024
    "…The yearly level of antibiotic use in CGE declined from 8.1% in 2020 to 3.9% in 2023, with a statistically significant annual percentage change (APC) of −21.3% (95% CI, −22.8 to −19.7). …"
  19. 7499

    Data Sheet 2_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf حسب Ditte Ljungquist (20446670)

    منشور في 2024
    "…The yearly level of antibiotic use in CGE declined from 8.1% in 2020 to 3.9% in 2023, with a statistically significant annual percentage change (APC) of −21.3% (95% CI, −22.8 to −19.7). …"
  20. 7500