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changes decrease » larger decrease (Expand Search), change increases (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
role decrease » fold decrease (Expand Search), rate decreased (Expand Search), road decreased (Expand Search)
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9021
Image 1_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tif
Published 2025“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”
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9022
Image 5_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png
Published 2025“…</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”
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9023
Table 2_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
Published 2025“…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”
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9024
Image 2_The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis.tif
Published 2025“…The sensorimotor network playing a key role in pain modulation, identifying neuroimaging differences in the sensorimotor network is crucial for detecting and intervening in TN, Forty TN patients underwent MVD surgery, with follow-up assessments conducted 6 months postoperatively and twenty-five healthy controls (HC) were recruited and scanned with resting state fMRI (rs-fMRI). …”
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9025
Table 4_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xls
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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9026
Table 1_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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9027
Data Sheet 1_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.docx
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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9028
Table 6_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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9029
Image 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif
Published 2025“…Introduction<p>Increasing evidence highlights the pivotal role of RNA methylation and miRNAs in hepatocellular carcinoma (HCC). …”
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9030
Image 3_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff
Published 2025“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”
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9031
Data Sheet 1_Therapeutic potential of Glycyrrhiza polysaccharides in pseudorabies virus infection: immune modulation, antioxidant activity, and gut microbiota restoration.pdf
Published 2025“…</p>Results<p>GP administration significantly alleviated PRV-induced symptoms, reduced mortality and disease activity index, and improved food intake. …”
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9032
Table 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx
Published 2025“…Introduction<p>Increasing evidence highlights the pivotal role of RNA methylation and miRNAs in hepatocellular carcinoma (HCC). …”
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9033
Data Sheet 1_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf
Published 2025“…Although fragile X messenger ribonucleoprotein is ubiquitously expressed, there is a dearth of knowledge regarding its role outside of the brain including effects on gut dysfunction in fragile X. …”
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9034
Image 4_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif
Published 2025“…Introduction<p>Increasing evidence highlights the pivotal role of RNA methylation and miRNAs in hepatocellular carcinoma (HCC). …”
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9035
Data Sheet 1_Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD.docx
Published 2025“…Flow cytometry confirmed significantly decreased NK cell counts and increased apoptosis in the ILD group. …”
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9036
Table 5_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.docx
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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9037
Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx
Published 2025“…Introduction<p>Increasing evidence highlights the pivotal role of RNA methylation and miRNAs in hepatocellular carcinoma (HCC). …”
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9038
Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip
Published 2025“…Background<p>PANoptosis is a newly recognized form of programmed inflammatory cell death implicated in numerous inflammation-related diseases. However, its precise role and underlying mechanisms in periodontitis (PD) remain unclear.…”
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9039
DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf
Published 2025“…<p>The role of the dynein light chain Tctex-type 3 (DYNLT3) protein in the biological behavior of cervical cancer and its relative molecular mechanisms were investigated. …”
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9040
Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
Published 2025“…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”