DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer by Varun Sasidharan Nair (5396393)

“…</p><h3>Results</h3><p dir="ltr">We found that the expression levels of PD-1, CTLA-4, TIM-3, TIGIT, PD-L1, and galectin-9 were significantly higher in colorectal tumor tissues, compared with colon normal tissues. …”

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery by Stephen L. Atkin (6684368)

“…MicroRNA expression was determined by quantitative polymerase chain reaction and tested for significant changes after surgery.</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">BMI decreased by 3.8 kg/m² 21 days postoperatively. …”

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers by Yadav, Santosh K.

“…ResultsHIC and HUC groups showed significantly decreased NP test scores in various domain compared to CHNM. …”
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A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats by Zeeni, Nadine

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Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury by Sebnem Garip Ustaoglu (18460611)

“…Band area and intensity ratios, band frequency and bandwidth values of specific spectral bands showed that TBI causes significant structural and contextual global changes including decrease in carbonyl content, unsaturated lipid content, lipid acyl chain length, membrane lipid order, total protein content, lipid/protein ratio, besides increase in membrane fluidity with an altered protein secondary structure and metabolic activity in hippocampus 24 h after injury. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…We validated a subset of differentially expressed LncRNAs with qRT-PCR and identified the most significantly enriched cellular functions associated with the relevant LncRNAs, among them MALAT1. …”

Chemical Characterization and Source Apportionment of PM_2.5 in Rabigh, Saudi Arabia by Shedrack R. Nayebare (19725382)

“…A factor analysis model (PMF) indicated the major sources of PM2.5 as <i>Soil</i> (Si, Al, Ti, Fe, Mg, K and Ca); Industrial Dust (Ca, Fe, Al, and Si); <i>Fossil-Fuel combustion</i> (V, Ni, Pb, Lu, Cu, Zn, NH⁴⁺, SO4^2– and BC); <i>Vehicular</i> <i>Emissions</i> (NO₃^–, C2O₄^2–, V and BC) and Sea Sprays (Cl^– and Na). …”

System biology approaches identified novel biomarkers and their signaling pathways involved in renal cell carcinoma with different human diseases by Md. Saddam Hossen (18278698)

Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis by HASHEM ABU SERHAN (19737499)

“…No significant changes were observed on IOP with mannitol administration when comparing vitrectomized versus non- vitrectomized eyes.…”

Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury by Fazle Rakib (5768069)

“…Significant decrease in methyl content and a significant increase in olefinic content were observed in Co and CC regions of mTBI rat brain tissues. …”

Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... by Farhat, Mirna

“…Both variants proved to be highly potent against tumors while having an enhanced selectivity and as such paved the way to create a modified intermolecularly complementing (IMC), PAU2R200A-PAL1I207R, version of PrAg that requires activation by both uPA/uPAR and MMPs proteases, simultaneously. …”
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Elemental compositions of particulate matter retained on air condition unit’s filters at Greater Doha, Qatar by Mohamed M. Mahfouz (14151000)

“…Similar or lower concentration values have been found for As, Cd, Cr, Cu, Mn, Ni, Pb, V, Zn, Al, and Fe compared to the international context of upper crust concentrations, NIST SRM (urban dust), published local dust information of outdoor, and surface terrestrial deposit (STD) counted for 7.2, 0.7, 91.8, 192.8, 369.7, 68.6, 65.3, 52.1, 824.3, 19,791, 20,508 mg/kg, respectively. The coefficient of correlation (<i>p</i> ≤ 0.05) showed significant association of ACUs dust elemental compositions with the main components of the local earth crust and surface deposits, ranging from the lowest 0.77 (Mg–Fe) to the highest 0.98 (Al–Fe), while Ni and V, typical anthropogenic pollutants, are also strongly correlated (0.86). …”

Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS by Myint Myint Aye (6404327)

Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta... by Mohammed M. Al-Humaiqani (18325554)

“…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. …”

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 by Razieh, Hassannejad

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Positional and dimensional temporomandibular joint osseous changes in patients treated with the forsus fatigue resistant device: a non-randomized clinical trial by Ramy Abdul-Rahman Ishaq (22928974)

“…In the treatment group, condylar width decreased significantly by 0.52 ± 0.92 mm, in contrast to an increase of 0.17 ± 0.35 mm in the control group (<i>P</i> = 0.010). …”

The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach by Hatem Zayed (835448)

Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: Perceived changes in diet, physical activity, and body weight by Muna Abed Alah (14779534)

“…The ordinal logistic regression analysis showed that the numbers of unhealthy dietary behaviors adopted by participants, and adverse changes in exercise, setting/reclining and screen times were significantly associated with weight gain. …”

Akkermansia, a Possible Microbial Marker for Poor Glycemic Control in Qataris Children Consuming Arabic Diet—A Pilot Study on Pediatric T1DM in Qatar by Arun Prasath Lakshmanan (16444663)

“…The results have revealed that the subjects who had undergone CSII therapy had increased microbial diversity and genus <i>Akkermansia</i> was significantly enriched in the subjects without CSII therapy. …”

Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030) by Khaled F. Alkaraki (22051967)

“…<p dir="ltr">Modeling the impacts of Land Use/Land Cover changes (LULCC) on Land Surface Temperature (LST) is crucial in understanding and managing urban heat islands, climate change, energy consumption, human health, and ecosystem dynamics. …”