Table6_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Image 3_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as... by Mohammad Golam Sabbir (15874493)

“…</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …”

Dopamine receptors D1, D2, and D4 modulate electrical synapses and excitability in the thalamic reticular nucleus supplementary table by Mitchell Vaughn (19871487)

“…<p dir="ltr">Table 1: All reported data on excitability, spiking, and electrical coupling of TRN neurons in control and experimental conditions from the manuscript titled: Dopamine receptors D1, D2, and D4 modulate electrical synapses and excitability in the thalamic reticular nucleus. Significant increases are highlighted green, and significant decreases are highlighted red.…”

Glucagon-like peptide 1 receptor agonists modestly reduced low-density lipoprotein cholesterol and total cholesterol levels independent of weight reduction: a meta-analysis and met... by Frederick Berro Rivera (12679463)

“…</p> <p>GLP-1RA treatment modestly decreased LDL-C and TC but did not significantly affect triglycerides, VLDL-C, or HDL-C.…”

Data Sheet 1_Efgartigimod for generalized myasthenia gravis in the extreme elderly (≥80 years): a multicenter retrospective real-world study.pdf by Ye Hong (2580841)

“…At week 4 (1week after the final infusion), the study showed significant reductions in all efficacy measurements: MG-ADL scores decreased by 52.2% ± 30.8% (from 10.9 ± 2.7 to 3.6 ± 2.1), QMG scores by 36.6% ± 28.4% (from 18.2 ± 7.0 to 11.7 ± 8.3), MGC scores by 48.2% ± 33.4% (from 17.8 ± 7.5 to 9.0 ± 8.6). …”

Dataset for the study Dissecting Oxidative Stress and Organismic Response to a Temperature Gradient in the midge <i>Chironomus riparius</i> by Burak Bulut (22295269)

“…Conversely, at high temperatures, the hydrogen peroxide group dominates, associated with increased metabolic rate and heat stress signaling pathways. …”

Table 1_Seeds of success: seed biology and germination response of Gazania weed in Australia.xlsx by Muhammad Adnan (678952)

“…Seedling emergence and root length decreased with increasing burial depth and no emergence was observed at 6 cm depth. …”

Appendix 2 - Tools and Outcomes from the Hybrid Roleplay Intervention by Dinus Salam (20306184)

“…Additionally, the NASA Task Load Index (NASA-TLX) results revealed significant reductions in mental, temporal, and effort demands, indicating a decreased cognitive load during documentation tasks. …”

Effect of Gasdermin-D inhibition on CER-induced pyroptosis in P_i<i>‐</i>treated VSMCs. by Razia Rashid Rahil (22772495)

“…(F-G) Representative western blots and summarized bar graph showed DIS significantly decreased protein expression of NLRP3 and GSDM-D in CER treated P_i‐induced VSMCs. …”

Effect of NLRP3 inhibition on CER-induced pyroptosis in P_i<i>‐</i>treated VSMCs. by Razia Rashid Rahil (22772495)

“…<p>Summarized bar graphs showed MCC950 significantly decreased mRNA expression of pyroptotic markers (A) NLRP3 (B) GSDM-D, proinflammatory cytokines (C) IL-1β (D) IL-18, and (E) Lactate dehydrogenase (LDH) release in CER treated P_i‐induced VSMCs. …”

Glucose and G-6-P levels modulate HK2-<i>SOX10</i> mRNA association and <i>SOX10</i> mRNA translation. by Ana Luisa Dian (22258504)

“…<p><b>(A)</b> Western blot analysis of HK2 and SOX10 protein level in A375 cells cultured for 24 h with decreasing concentrations of glucose or under glucose starvation, as indicated. …”

30-year trends in incidence of acute STEMI and NSTEMI in the Belgian Province of Luxembourg. A long-term follow-up of the MONICA-BELLUX registry by Bernhard L. Gerber (10171583)

“…</p><p>b) What this study adds</p><p>In a 30-year registry in Luxembourg using modern AMI definitions, overall, AMI incidence decreased significantly, primarily due to a 3.8-fold reduction in STEMI.…”

Density-dependent effects of simultaneous root and floral herbivory on plant fitness and defense by Martin Aguirrebengoa (5938490)

“…We found that the fitness impact of both herbivore groups was independent and density-dependent. Increasing root herbivore density non-significantly reduced plant fitness, while the relationship between increasing floral herbivore density and the reduction they caused in both seed number and seedling emergence was non-linear. …”

Table 1_Investigating the Gut Microbiota Profile in Prehypertensive Individuals Exhibiting Phlegm-Dampness Constitution.docx by Ning Yu (358970)

“…Although the body may experience pathological changes at this stage, there are often no symptoms. …”

Supplementary file 1_Effects of microbial organic fertilizers on soil microbial communities and physicochemical properties in tobacco cultivation.docx by Shengli Wang (4318522)

“…<p>Introduction: Tobacco, as an economic crop in our country, not only requires changes in cultivation practices but also benefits from reasonable fertilization to enhance yield and quality. …”

Data Sheet 1_Assessment of the effect of social media use on medical students’ academic performance: cross-sectional study from Jordan.pdf by Hana Taha (4747014)

“…GPA was significantly associated with more time spent on social media (OR: 0.476; 95%CI: 0.278–0.813; p = 0.022). …”

Image 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.tiff by Yulia Dwi Setia (21590591)

“…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …”

Data Sheet 1_Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis.docx by Shubin Wang (3105348)

“…</p>Results<p>It was shown that during DSS-induced colitis, small intestine underwent a serious injury process, including dysregulated integrity and decreased proliferation of ISCs. Iron overload significantly exacerbated intestinal injury in tissues, epithelial cell line, and intestinal organoids. …”

Consort flow diagram of the participants. by Preeyaphorn Songsorn (21799601)

“…During flow incentive spirometry, stroke volume and heart rate significantly increased, while cardiac output significantly decreased compared to volume incentive spirometry and costal breathing exercises with sustained maximal inspiration throughout the 10 breathing cycles.…”

Table 2_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.xlsx by Yulia Dwi Setia (21590591)

“…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …”