Loss of b-cell K_ATP reduces Ca²⁺ sensitivity of insulin secretion and <i>Trpm5</i> expression by Nathaniel W. York (20410828)

“…</a><a href="" target="_blank">Glibenclamide pellet-implanted <i>Trpm5</i> KO mice also exhibited significant glucose intolerance. However, this was not as severe as in WT animals, which suggests that decreased expression of <i>Trpm5</i> may play a small role in the disruption of insulin secretion with K_ATP loss.…”

Image4_Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin.J... by Fereshteh Sadeghian (19848177)

“…On the inner surface of the spermathecal tube, tension on the apical junctions is decreased by depletion of PLC-1 and NMY-1. Surprisingly, when basal contractility is increased through SPV-1 depletion, the tension on apical junctions also decreases, with the most significant effect on the junctions aligned in perpendicular to the axis of the spermatheca.…”

Video3_Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin.A... by Fereshteh Sadeghian (19848177)

“…On the inner surface of the spermathecal tube, tension on the apical junctions is decreased by depletion of PLC-1 and NMY-1. Surprisingly, when basal contractility is increased through SPV-1 depletion, the tension on apical junctions also decreases, with the most significant effect on the junctions aligned in perpendicular to the axis of the spermatheca.…”

Table 1_Effect of low salicylate diet and blood salicylate level on the symptom control of chronic spontaneous urticaria.docx by Sercan Guloglu (22801190)

“…The CU-Q2oL scores significantly decreased from 33.7 to 20.7 (p < 0.001) and the UAS4 significantly decreased from 14 to 8 (p < 0.001) after low salicylate diet when compared to baseline (low scores mean less complaints). …”

Table 2_Genomic analysis, culturing optimization, and characterization of Escherichia bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce.docx by Mustafa Yesil (20403140)

“…Incubation for 30 min at 4°C−47°C or pH 4–11 had no significant detrimental effect (p > 0.05) on phage infectivity. …”

Table 3_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Data Sheet 1_HIV drug resistance and its associated factors among patients during interruption of antiretroviral therapy in China.docx by Zhongbao Zuo (3594755)

“…The HIV drug resistance rate and the frequency of patients harboring ≥2 drug resistance mutations decreased significantly in the longer interruption time group. …”

Data Sheet 1_Hyperbaric oxygen therapy for radiation enteritis and clinical parameters: a systematic review and meta-analysis.docx by Yuhan Wang (595964)

“…Moderate-quality evidence suggested that HBOT could significantly reduce the incidence of RE [OR = 0.32, 95% CI (0.14, 0.72), P = 0.006], particularly showing a significant advantage in decreasing the incidence of grade 3 or higher RE according to the RTOG/EORTC criteria [OR = 0.37, 95% CI (0.17, 0.82), P = 0.01]. …”

Table 1_Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease.docx by Xi Luo (361139)

“…Both PD models predicted reduced uptake of lysine and lactate, indicating coordinated metabolic processes between these components. In contrast, decreased methionine and urea uptake was exclusively predicted in the synaptic PD model, while decreased histidine and glyceric acid uptake was exclusive to the non-synaptic PD model. …”

Rescue of <i>pbp1</i>-KD phenotypes using CRISPRi trans-complementation. by Gregory A. Harrison (16639446)

“…Yellow arrows point to a subset of PBP1-depleted cells that have decreased RADA signal, likely due to decreased peptidoglycan metabolism. …”

Video1_Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin.A... by Fereshteh Sadeghian (19848177)

“…On the inner surface of the spermathecal tube, tension on the apical junctions is decreased by depletion of PLC-1 and NMY-1. Surprisingly, when basal contractility is increased through SPV-1 depletion, the tension on apical junctions also decreases, with the most significant effect on the junctions aligned in perpendicular to the axis of the spermatheca.…”

Image 1_Activation of mechanoreceptor Piezo1 inhibits enteric neuronal growth and migration in vitro.jpeg by Chioma Moneme (20457845)

“…Piezo1 inhibition also led to significantly increased neuronal migration, whereas Piezo1 activation resulted in significantly decreased neuronal migration and slower neuronal recovery from injury.…”

Table 1_Genomic analysis, culturing optimization, and characterization of Escherichia bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce.docx by Mustafa Yesil (20403140)

“…Incubation for 30 min at 4°C−47°C or pH 4–11 had no significant detrimental effect (p > 0.05) on phage infectivity. …”

The global disability-adjusted life years (DALYs) for asthma attributable to nitrogen dioxide pollution from 1990 to 2021 and predicted the trends from 2022 to 2050 by Yaping Feng (427666)

“…Additionally, it is still quite significant for children under the age of 15 and in some underdeveloped regions.…”

Table 1_Evaluation of hypoxia-inducible factor-1α and urine non-transferrin-bound iron concentrations in cats with chronic kidney disease.docx by Chien-Hui Chen (2524213)

“…/mL in early-stage CKD cats but decreased to 8.50 pg./mL in late-stage CKD cats. uHIF-1α concentrations gradually decreased with a significant difference between the control group (44.61 pg.…”

Data Sheet 1_Population pharmacokinetics/pharmacodynamics and safety of YPEG-rhGH in elderly subjects.docx by Yajie He (20323682)

“…In the final model, AGE was identified as a significant covariate for K_a, V₁/F, and V_max, while WEIGHT significantly influenced V_max. …”

Table 4_Seeing beyond words: nanotechnology in hepatocellular carcinoma - a bibliometric study.docx by Talaiti Tuergan (11522500)

“…Background<p>Nanotechnology has increasingly been applied in the diagnosis and treatment of hepatocellular carcinoma (HCC) over the past two decades. …”

Table 7_Seeing beyond words: nanotechnology in hepatocellular carcinoma - a bibliometric study.docx by Talaiti Tuergan (11522500)

“…Background<p>Nanotechnology has increasingly been applied in the diagnosis and treatment of hepatocellular carcinoma (HCC) over the past two decades. …”

Video 1_Uncharted territory: the arrival of Psychoda albipennis (Zetterstedt, 1850) (Diptera: Psychodidae) in Maritime Antarctica.mp4 by Jordan Hernandez-Martelo (20438549)

“…Thus, once established in the natural environment of King George Island there appears to be a high risk of the species rapidly becoming invasive. The introduction of non-native species such as P. albipennis can be a significant driver of future biodiversity change and loss, and seriously impact ecosystem health. …”

Data Sheet 1_Real-world evidence from a multi-center pediatric network: greenness exposure and autism spectrum disorder in urban China.pdf by Wenxu Yang (19852487)

“…Introduction<p>Childhood autism spectrum disorder (ASD) is a global public health concern and its prevalence is increasing rapidly in developing countries such as China. …”