The oxylipins profile and their associations with embryo quality of women with polycystic ovary syndrome: a prospective cohort study by Ye Tian (220278)

“…</p> <p>We conducted a targeted lipidomic study involving sixty-two cases of PCOS and age-matched controls (Cohort 1) <i>via</i> UHPLC–MS. …”

Supplementary Material for: A Newly Launched Nationwide Database Revealed Real-world Evidence on Systemic Therapy for Unresectable Hepatocellular Carcinoma in Japan: Hepatoma Regis... by figshare admin karger (2628495)

“…However, the limited settings of phase III clinical trials necessitate large-scale real-world data to evaluate effective treatment sequences. …”

Behavioral characterization of prenatal nicotine exposure (PNE) and control mice. by Rodrigo Vidal (4177060)

“…Quantification of the average total distance traveled. Significant differences were observed between PNE animals and control mice (PNE: 78.37 ± 2.01 m; n = 6; Control = 51.57 ± 3.33 m; n = 6), t = 6,883 df = 10, p < 0,0001. …”

The effect of inulin treatment on plasma untargeted metabolomic profiles in mice of diverse groups. by Ke Li (106849)

“…Color key in the heat map represents the metabolite expression value: red represents the significant increases and blue stands for the remarkable decreases. …”

Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Cilium disassembly defects were rescued with ectopic expression of CCDC66 but not CEP104. by Jovana Deretic (13113617)

“…Mean cilia length measured in 3D in CCDC66 depletion is decreased to 0.97-fold of the mean control length. …”

Image 3_Genomic instability and CCNE1 amplification as emerging biomarkers for stratifying high-grade serous ovarian cancer.tif by Elena Conca (12376825)

“…Treatment with PARP-inhibitors has significantly improved survival in patients with high-grade serous cancer (HGSC) bearing BRCA1/2 mutations (~22% of the cases), and/or homologous recombination deficiency (HRD, ~50%). …”

Table 1_Genomic instability and CCNE1 amplification as emerging biomarkers for stratifying high-grade serous ovarian cancer.xlsx by Elena Conca (12376825)

“…Treatment with PARP-inhibitors has significantly improved survival in patients with high-grade serous cancer (HGSC) bearing BRCA1/2 mutations (~22% of the cases), and/or homologous recombination deficiency (HRD, ~50%). …”

Image 4_Genomic instability and CCNE1 amplification as emerging biomarkers for stratifying high-grade serous ovarian cancer.tif by Elena Conca (12376825)

“…Treatment with PARP-inhibitors has significantly improved survival in patients with high-grade serous cancer (HGSC) bearing BRCA1/2 mutations (~22% of the cases), and/or homologous recombination deficiency (HRD, ~50%). …”

Image 2_Genomic instability and CCNE1 amplification as emerging biomarkers for stratifying high-grade serous ovarian cancer.tif by Elena Conca (12376825)

“…Treatment with PARP-inhibitors has significantly improved survival in patients with high-grade serous cancer (HGSC) bearing BRCA1/2 mutations (~22% of the cases), and/or homologous recombination deficiency (HRD, ~50%). …”

Image 1_Genomic instability and CCNE1 amplification as emerging biomarkers for stratifying high-grade serous ovarian cancer.tif by Elena Conca (12376825)

“…Treatment with PARP-inhibitors has significantly improved survival in patients with high-grade serous cancer (HGSC) bearing BRCA1/2 mutations (~22% of the cases), and/or homologous recombination deficiency (HRD, ~50%). …”

Image 5_Genomic instability and CCNE1 amplification as emerging biomarkers for stratifying high-grade serous ovarian cancer.tif by Elena Conca (12376825)

“…Treatment with PARP-inhibitors has significantly improved survival in patients with high-grade serous cancer (HGSC) bearing BRCA1/2 mutations (~22% of the cases), and/or homologous recombination deficiency (HRD, ~50%). …”

Table 2_Genomic instability and CCNE1 amplification as emerging biomarkers for stratifying high-grade serous ovarian cancer.xlsx by Elena Conca (12376825)

“…Treatment with PARP-inhibitors has significantly improved survival in patients with high-grade serous cancer (HGSC) bearing BRCA1/2 mutations (~22% of the cases), and/or homologous recombination deficiency (HRD, ~50%). …”

Additional file 6 of NSDHL contributes to breast cancer stem-like cell maintenance and tumor-initiating capacity through TGF-β/Smad signaling pathway in MCF-7 tumor spheroid by So-Hyun Yoon (5353250)

“…Supplementary Material 6: Figure S6. A-83-01 (50 µM) decreased the phosphorylation of both SMAD2 and SMAD3 but did not show significant toxicity in MCF-7-spheroids. …”

Disturbances in drylands: Interactions among herbivory, drought, and termite activity in savanna plant communities by Harry Wells (11430190)

“…We used 15 years of a 28-year experiment spanning several significant droughts to investigate how rainfall, large herbivores, and soil-engineering termites affect understory vegetation in a semi-arid savanna. …”