Supplementary file 1_Case Report: Loss-of-function TRPM4 mutation p.L91Δ implicated in progressive cardiac conduction defect.docx by Anne-Flore Hämmerli (18121647)

“…Functional experiments using the patch-clamp approach demonstrated a significant decrease in TRPM4 current, consistent with the biochemical observations.…”

Data Sheet 1_Dose-response of tomato fruit yield to far-red fraction in supplementary lighting.docx by Elena Vincenzi (15444443)

“…We conclude that adding FR to supplementary lighting can increase tomato fruit yield linearly up to an FR fraction of 0.40, while at higher FR fractions, further increases in FR have limited or even negative effects on yield and decrease radiation and electricity use efficiency.…”

Supplementary file 1_Dynamic reconfiguration and transition of whole-brain networks in patients with MELAS revealed by a hidden Markov model.docx by Qingyun Yu (18837625)

“…Based on HMM, fractional occupancies in states 5 and 6 for MELAS were significantly decreased (p < 0.001), but fractional occupancies in states 2, 3, 4, 7, 8, 9, 10, and 11 were significantly increased (p < 0.05), compared to HCs. …”

Additional file 2 of Gut Microbiome dysbiosis and immune activation correlate with somatic and neuropsychiatric symptoms in COVID-19 patients by Paula L. Scalzo (20882386)

“…Conversely, (i) Albumin levels decrease with increasing severity, with significant reductions in the critical group compared to low and moderate groups. …”

Supplemental Tables S1-S5 by Carolyn Morris (21298187)

“…LFD and HFD mice lost an average of 11% and 27% of their body weight, respectively. LFD mice had a 33% decrease in CCL20 in lung tissue and a 55% decrease in neutrophils in BALF. …”

Supplemental Figs. S1-S7 by Carolyn Morris (21298187)

“…LFD and HFD mice lost an average of 11% and 27% of their body weight, respectively. LFD mice had a 33% decrease in CCL20 in lung tissue and a 55% decrease in neutrophils in BALF. …”

Supplementary Material for: Trends in the Incidence of Rare Eyelid Malignancies: A SEER-Based Study (2000–2021) by figshare admin karger (2628495)

“…For MCC; NNAR (2,2) model showed IR stability (0.003-0.008), with a slight drop in 2021 (IR = 0.006), and predicted to decrease to 0.01 (95% PI: 0-0.01). For SGC; ARIMA (0,0,0) model demonstrated a decline in IR in 2011 (IR = 0.0192), increase until 2019, then decrease in 2021 (IR = 0.0246), with a predicted 10-year decrease to 0.026 (95% PI: 0.019–0.032). …”

Data Sheet 1_Grassland restoration impacts human-wildlife and social conflicts in the Chyulu Hills, Kenya.docx by Camila I. Donatti (8442690)

“…There was a negative and significant correlation between the area restored in each site and both the number of human-wildlife conflicts and the number of social conflicts, showing that conflicts decrease as restoration increases. …”

Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Table 3_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Table 1_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Data Sheet 3_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Causal impacts of 731 immunocyte phenotypes on colorectal cancer-evidence from a bidirectional two-sample Mendelian randomization by Xinyue Gu (7335398)

“…The inverse variance weighting results indicated that a total of 31 and 28 immune cell phenotypes significantly associated with colorectal cancer in two different datasets, respectively. …”

Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Table 2_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Data Sheet 1_Isoform-specific vs. pan-histone deacetylase inhibition as approaches for countering glioblastoma: an in vitro study.docx by Ameya Joshi (1290186)

“…The non-specific inhibitor Vorinostat surprisingly promoted migration in the cells at its 2D IC50 value treatment, and none of the inhibitors was able to significantly decrease late resistance compared to untreated controls, indicating the need for the development of more potent HDAC inhibitors for monotherapy for GBM.…”

Data Sheet 1_Stellate ganglion blockade under ultrasound-guidance and the physiological responses in the rat.pdf by Robert M. N. Tran (20539130)

“…Heart rate (HR) was significantly decreased after administration of lidocaine (344 ± 32 to 289 ± 47 bpm; p = 0.015, pre-vs. after-injection), but not after normal saline, into the right SG. …”

The in vitro and in vivo effect of a chemokine inhibitor CTCE-9908 in combination with Kynurenine metabolites on tumour adhesion by Danielle Tatchum (16946574)

“…Results showed a statistically significant decrease in the percentage cell number in L-kyn- and CTCE-9908-treated sEnd-2 cells when compared to the vehicle control, suggesting the inhibitory effect of the compounds on adhesion. …”

SEAwise Report on improved predictive models of growth, production and stock quality under different habitat scenarios and incorporating experimental results by Leire Ibaibarriaga (13760979)

“…The third study in the Western Waters analysed relative condition factor in the Bay of Biscay and the Celtic Sea and found significantly decrease over time for 12 species, while two species showed an increase, and three species showed no significant trends. …”

Data_Sheet_1_Effects of a 30-min rest with a nap chair on task performance, sleepiness, and neurophysiological measures in men with suspected brain fatigue: a randomized controlled... by Minoru Fujino (12742196)

“…The Karolinska Sleepiness score significantly decreased after the nap-chair rest, and the between-treatment difference in the decrease was highly significant (P = 0.0004). …”