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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
clinical decrease » clinical disease (Expand Search), clinical case (Expand Search), clinical areas (Expand Search)
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17921
Data Sheet 1_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf
Published 2025“…Drug resistance in Mycobacterium tuberculosis (Mtb) is another significant and persistent public health concern. The development of effective TB vaccines and treatments requires a better understanding of the intricate interactions between M. tuberculosis and host immunity. …”
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17922
Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx
Published 2025“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”
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17923
Space-to-depth convolution.
Published 2025“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”
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17924
Data Sheet 2_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf
Published 2025“…Drug resistance in Mycobacterium tuberculosis (Mtb) is another significant and persistent public health concern. The development of effective TB vaccines and treatments requires a better understanding of the intricate interactions between M. tuberculosis and host immunity. …”
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17925
Table 4_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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17926
Value ranges of three representative points.
Published 2025“…<div><p>Capturing congestion propagation among different facilities at intersections in dynamic stochastic traffic environments poses significant challenges, particularly under oversaturated conditions. …”
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17927
Table 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.docx
Published 2025“…A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…”
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17928
Data augmentation.
Published 2025“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”
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17929
Image 1_Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials.jpeg
Published 2025“…Protein adsorption to the membrane types did not vary to a large extent, but a decreased flow rate significantly reduced the differences in protein adsorption between both membrane types and led to the adhesion of significantly higher amounts of inhibitory proteins C1INH and α1-AT. …”
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17930
Data Sheet 1_Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8.pdf
Published 2025“…In the AR + Derp1 group, TSLP was higher, and CCL1 protein levels were decreased. There were no significant differences in IL-25, TGF-β and IL-10. …”
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17931
Data Sheet 7_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di...
Published 2025“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
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17932
Table 7_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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17933
Signalized intersection in Kunshan.
Published 2025“…<div><p>Capturing congestion propagation among different facilities at intersections in dynamic stochastic traffic environments poses significant challenges, particularly under oversaturated conditions. …”
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17934
Table 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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17935
DataSheet1_Pressure-tolerant survival mechanism of Schizophyllum commune 20R-7-F01 isolated from deep sediments 2 kilometers below the seafloor.csv
Published 2024“…By assessing the cell viability, biomass, and cell wall thickness changes of strain 20-7-1 under different HHP conditions, we observed that, compared to 0.1 MPa, strain 20-7-1 exhibited slower growth rates and decreased cell viability at 15 MPa and 35 MPa, yet demonstrated significant pressure tolerance. …”
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17936
Image 2_Biometric parameters and choroidal microstructure in Chinese children with unilateral anisometropia.pdf
Published 2025“…The TCA and LA were significantly greater in hyperopic eyes and significantly lower in myopic eyes compared to normal eyes (all p <0.005). …”
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17937
spss data sheet for research work titled "PHYSICAL ACTIVITY AND HEALTHY EATING HABITS IN RELATION TO BODY ADIPOSITY INDEX AMONG OFFICE WORKERS IN THE PROVINCE OF KHYBER PAKHTUNKHWA...
Published 2025“…Increase in physical activity decreases the BAI value and vice versa. Similarly healthier eating habits lead to lower BAI.…”
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17938
Table 1_Research on the changes in the disease burden of nasopharyngeal carcinoma caused by global occupational formaldehyde exposure from 1990 to 2021 and prediction of future tre...
Published 2025“…Geographically, there are significant differences in the disease burden among different countries and regions, with South Asia, East Asia, and Africa having the highest disease burden. …”
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17939
Data Sheet 2_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx
Published 2025“…</p>Discussion<p>The capacity for infectious disease prevention and control among Guangxis grassroots hospital physicians has significantly improved following COVID-19. The high engagement in related training and emergency response efforts reflects a strong sense of professional identity and commitment. …”
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17940
<b>Single-cell landscape of piglet lung response with </b><b><i>Actinobacillus pleuropneumoniae</i></b>
Published 2025“…In contrast, epithelial cells were significantly decreased and included those with features of epithelial-mesenchymal transition differentiated into fibroblasts through the signalling of TGFB1 and HIF1A. …”