Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …”

Aβ and vGlut2 staining of 6-, 9-, and 12-month dLGN sections show significant plaque load and accelerated loss of retinal ganglion cell axon terminals in the 5xFAD mice. by Shaylah McCool (20818280)

Mean muscle activation patterns across the gait cycle during walking with mediolateral (ML) forces for <i>A)</i> able-bodied individuals and <i>B)</i> individuals after stroke duri... by Sanne Ettema (18786312)

Levels of antioxidant enzymes (A) Catalase, (B) Superoxide dismutase, (C) peroxidase. by Hammad Ismail (4227988)

Impact of sludge dosage on HPST. by Peng Zhao (128233)

“…The model optimization and experimental validation showed that the optimal HPST conditions for treating domestic sewage were as follows: the dosage of polyaluminum chloride (PAC) was 1.70 g/L, cationic polyacrylamide (CPAM) dosage was 2.35 mg/L, sewage pH was maintained at 8.0, sludge dosage was 10 mL/L, stirring time lasted for 5 minutes, and settling time lasted for 30 minutes. As a result of these optimized conditions, the turbidity of treated sewage decreased to 1.19 NTU.…”

Impact of settling time on HPST. by Peng Zhao (128233)

“…The model optimization and experimental validation showed that the optimal HPST conditions for treating domestic sewage were as follows: the dosage of polyaluminum chloride (PAC) was 1.70 g/L, cationic polyacrylamide (CPAM) dosage was 2.35 mg/L, sewage pH was maintained at 8.0, sludge dosage was 10 mL/L, stirring time lasted for 5 minutes, and settling time lasted for 30 minutes. As a result of these optimized conditions, the turbidity of treated sewage decreased to 1.19 NTU.…”

ANOVAs for the response surface of Eq (2). by Peng Zhao (128233)

“…The model optimization and experimental validation showed that the optimal HPST conditions for treating domestic sewage were as follows: the dosage of polyaluminum chloride (PAC) was 1.70 g/L, cationic polyacrylamide (CPAM) dosage was 2.35 mg/L, sewage pH was maintained at 8.0, sludge dosage was 10 mL/L, stirring time lasted for 5 minutes, and settling time lasted for 30 minutes. As a result of these optimized conditions, the turbidity of treated sewage decreased to 1.19 NTU.…”

Impact of CPAM dosage on HPST. by Peng Zhao (128233)

“…The model optimization and experimental validation showed that the optimal HPST conditions for treating domestic sewage were as follows: the dosage of polyaluminum chloride (PAC) was 1.70 g/L, cationic polyacrylamide (CPAM) dosage was 2.35 mg/L, sewage pH was maintained at 8.0, sludge dosage was 10 mL/L, stirring time lasted for 5 minutes, and settling time lasted for 30 minutes. As a result of these optimized conditions, the turbidity of treated sewage decreased to 1.19 NTU.…”

Impact of sewage pH on HPST. by Peng Zhao (128233)

“…The model optimization and experimental validation showed that the optimal HPST conditions for treating domestic sewage were as follows: the dosage of polyaluminum chloride (PAC) was 1.70 g/L, cationic polyacrylamide (CPAM) dosage was 2.35 mg/L, sewage pH was maintained at 8.0, sludge dosage was 10 mL/L, stirring time lasted for 5 minutes, and settling time lasted for 30 minutes. As a result of these optimized conditions, the turbidity of treated sewage decreased to 1.19 NTU.…”

Impact of PAC dosage on HPST. by Peng Zhao (128233)

“…The model optimization and experimental validation showed that the optimal HPST conditions for treating domestic sewage were as follows: the dosage of polyaluminum chloride (PAC) was 1.70 g/L, cationic polyacrylamide (CPAM) dosage was 2.35 mg/L, sewage pH was maintained at 8.0, sludge dosage was 10 mL/L, stirring time lasted for 5 minutes, and settling time lasted for 30 minutes. As a result of these optimized conditions, the turbidity of treated sewage decreased to 1.19 NTU.…”

Food intake in groups A, B and C. by Sohail Afzal (10850709)

“…Statistically, there was a significant decrease in EPG values from days 0–14. …”

Overexpression <i>TRIM37</i> promotes myelin repair and inhibits cell apoptosis by upregulating PEX5. by Lai Jiang (2401513)

“…<p><b>(a, b)</b> Western blot (n = 3) showed a significant increase in PEX5 protein levels in the OE-TRIM37 group compared to the LPC group. …”

Alterations in CBC parameters in albino rats of both genders after 60 days of administration of dimethoate presented in Mean ± S.E.M. and their significance level. by Nida Saleem (17194610)

Subjects:

Alterations in CBC parameters in albino rats of both genders after 30 days of administration of dimethoate presented in Mean ± S.E.M. and their significance level. by Nida Saleem (17194610)

Subjects: