Estimated difference in ECG in milliseconds (BE-PEP (bedaquiline 800 mg + rifampicin 600 mg)—SDR-PEP (rifampicin 600 mg)) and 95% confidence intervals by age-group. by Bouke Catherine de Jong (4557247)

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Participant counts^b'*' with drug-related adverse events by preferred term and body system. by Bouke Catherine de Jong (4557247)

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Study timeline. Created with Biorender.com. by Bouke Catherine de Jong (4557247)

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ECG results (QTc) in ms by allocation arm and age-group in per protocol analysis. by Bouke Catherine de Jong (4557247)

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Box plots of QTc values on 12-lead ECG on day 0 (pre-drug administration) and day 1 (post-drug administration) by allocation arm for all ages. by Bouke Catherine de Jong (4557247)

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Summary of safety analysis by age-group. by Bouke Catherine de Jong (4557247)

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Characteristics of the study population at randomization. by Bouke Catherine de Jong (4557247)

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Data Sheet 1_Biomarker-based risk assessment of dietary intervention in patients with coronary artery disease during cardiac rehabilitation—a quasi-experimental study.pdf by Mona Kotewitsch (12479136)

“…Total cholesterol, LDL, and triglyceride levels also decreased in all groups during CR without significant differences (p ≥ 0.3957). …”

Image 1_Multi-omics analysis reveals the efficacy of two probiotic strains in managing feline chronic kidney disease through gut microbiome and host metabolome.pdf by Hsiao-Wen Huang (2349427)

“…During this period, creatinine and blood urea nitrogen levels were stabilized or reduced in most cats, and gut-derived uremic toxins (GDUTs) showed modest numerical reductions without statistically significant changes. Lm intervention was also associated with increased gut microbial diversity, alterations in specific bacterial taxa, and upregulation of microbial functions involved in GDUTs and short-chain fatty acid (SCFAs) biosynthesis pathways. …”

Table 1_Multi-omics analysis reveals the efficacy of two probiotic strains in managing feline chronic kidney disease through gut microbiome and host metabolome.docx by Hsiao-Wen Huang (2349427)

“…During this period, creatinine and blood urea nitrogen levels were stabilized or reduced in most cats, and gut-derived uremic toxins (GDUTs) showed modest numerical reductions without statistically significant changes. Lm intervention was also associated with increased gut microbial diversity, alterations in specific bacterial taxa, and upregulation of microbial functions involved in GDUTs and short-chain fatty acid (SCFAs) biosynthesis pathways. …”

Table 1_Global, regional, and national metabolic risk factors associated with multiple myeloma, 1990-2021: analysis via the global burden of disease study 2021.docx by Guozhi Zhang (511138)

“…</p>Key findings<p>From 1990 to 2021, global deaths from metabolic-related MM tripled, with DALYs increasing by 2.8 times. Mortality rates, ASMR, and ASDR showed significant upward trends—slowing between 2000 and 2010 before rebounding. …”

The actual image of the designed device. by Niloofar Jaafari (20565217)

Supplementary file 1_Global, regional, and national burden of iodine deficiency for women of reproductive age, 1990–2021: a systematic analysis based on the Global Burden of Diseas... by Taotao Wang (115296)

“…The significant absolute and relative health inequality was also observed and the gap has been narrowed.…”

Optical coherence tomography reveals impaired contraction with HFD treatment. by Rachel M. Andrews (5333966)

Vaccinated along with campaigns. by Mirjana Štrbac (8292462)

All vacccinated by years. by Mirjana Štrbac (8292462)

Image 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”

Image 6_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”

Image 5_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”

Image 4_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”