Data Sheet 1_Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in mice.pdf by Kaori Sakurai (1272567)

“…Introduction<p>Lung cancer is characterized by a poor prognosis and is a significant comorbidity of chronic obstructive pulmonary disease (COPD). …”

Hypha-associated gene expression of the oak tree isolates and the sugar-adapted strain on epithelial cells. by Theresa Lange (22403918)

Table 1_Association between vitamin D levels and preserved ratio impaired spirometry: an investigation of mediating roles of systemic inflammation and metabolic indicators.xlsx by Tong Lin (33562)

“…PRISm has been associated with various health issues, including an increased risk of metabolic disorders and cardiovascular diseases. …”

Sugar-evolved strain characterization. by Theresa Lange (22403918)

Virulence of the parental Oak 1 isolate and the sugar-adapted Evo strain in a transwell assay and a complex gut-on-chip model. by Theresa Lange (22403918)

Image 1_Meibomian gland alterations in allergic conjunctivitis: insights from a novel quantitative analysis algorithm.pdf by Jingting Wei (20506535)

“…Additionally, despite an increased number of MG, tear film stability was not improved.…”

Information of core targets. by Guobing Wang (288885)

“…The difference between the single drug group and the corresponding low dose group was significant (P<0.001). After Hela cells were cultured for 72 h, the mRNA and protein expressions corresponding to EGFR, TNF-α, VEGFA, PI3K, AKT and MDM2 were decreased in the experimental group compared with the control group as confirmed by RT-PCR and Western blot, and the extent of the decrease was more obvious with the increase of the drug concentration, and under the condition of the same drug dosage, the effect of the Baicalein group was more pronounced than that of the Wogonin group, and the effect was more obvious in the two-drug group compared with the single-drug group (P<0.05).…”

Composition of Scutellaria Barbata. by Guobing Wang (288885)

“…The difference between the single drug group and the corresponding low dose group was significant (P<0.001). After Hela cells were cultured for 72 h, the mRNA and protein expressions corresponding to EGFR, TNF-α, VEGFA, PI3K, AKT and MDM2 were decreased in the experimental group compared with the control group as confirmed by RT-PCR and Western blot, and the extent of the decrease was more obvious with the increase of the drug concentration, and under the condition of the same drug dosage, the effect of the Baicalein group was more pronounced than that of the Wogonin group, and the effect was more obvious in the two-drug group compared with the single-drug group (P<0.05).…”

GO function enrichment analysis. by Guobing Wang (288885)

“…The difference between the single drug group and the corresponding low dose group was significant (P<0.001). After Hela cells were cultured for 72 h, the mRNA and protein expressions corresponding to EGFR, TNF-α, VEGFA, PI3K, AKT and MDM2 were decreased in the experimental group compared with the control group as confirmed by RT-PCR and Western blot, and the extent of the decrease was more obvious with the increase of the drug concentration, and under the condition of the same drug dosage, the effect of the Baicalein group was more pronounced than that of the Wogonin group, and the effect was more obvious in the two-drug group compared with the single-drug group (P<0.05).…”

KEGG functional enrichment analysis. by Guobing Wang (288885)

“…The difference between the single drug group and the corresponding low dose group was significant (P<0.001). After Hela cells were cultured for 72 h, the mRNA and protein expressions corresponding to EGFR, TNF-α, VEGFA, PI3K, AKT and MDM2 were decreased in the experimental group compared with the control group as confirmed by RT-PCR and Western blot, and the extent of the decrease was more obvious with the increase of the drug concentration, and under the condition of the same drug dosage, the effect of the Baicalein group was more pronounced than that of the Wogonin group, and the effect was more obvious in the two-drug group compared with the single-drug group (P<0.05).…”

Supplementary file 1_Folic acid supplementation ameliorates alcohol-induced hepatic steatosis by inhibiting SREBP-1c-mediated lipogenesis.docx by Chen Liang (196452)

“…Background<p>Alcoholic fatty liver disease (AFLD), a prevalent yet reversible stage of alcoholic liver pathology, is often associated with folate deficiency. …”

Table 1_Global burden trends of tension-type headache, 1990–2021: socio-demographic patterns, age-period-cohort effects, and frontier analysis from the GBD 2021 study.docx by Can Wang (157994)

“…Contrasting trends emerged: globally and in High and High-middle SDI regions rates decreased, while Middle SDI regions showed significant increases (prevalence: +5.83%). …”

Table 2_Global burden trends of tension-type headache, 1990–2021: socio-demographic patterns, age-period-cohort effects, and frontier analysis from the GBD 2021 study.docx by Can Wang (157994)

“…Contrasting trends emerged: globally and in High and High-middle SDI regions rates decreased, while Middle SDI regions showed significant increases (prevalence: +5.83%). …”

Image 3_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.jpeg by Caini Mu (20997938)

“…An analysis of risk factors indicated that DALYs associated with ambient particulate matter pollution increased by 0.7% since 1990, while DALYs from Household air pollution in solid fuels decreased by 1.4%. …”

Image 1_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.jpeg by Caini Mu (20997938)

“…An analysis of risk factors indicated that DALYs associated with ambient particulate matter pollution increased by 0.7% since 1990, while DALYs from Household air pollution in solid fuels decreased by 1.4%. …”

Table 1_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.docx by Caini Mu (20997938)

“…An analysis of risk factors indicated that DALYs associated with ambient particulate matter pollution increased by 0.7% since 1990, while DALYs from Household air pollution in solid fuels decreased by 1.4%. …”

Image 4_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.jpeg by Caini Mu (20997938)

“…An analysis of risk factors indicated that DALYs associated with ambient particulate matter pollution increased by 0.7% since 1990, while DALYs from Household air pollution in solid fuels decreased by 1.4%. …”

Image 2_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.jpeg by Caini Mu (20997938)

“…An analysis of risk factors indicated that DALYs associated with ambient particulate matter pollution increased by 0.7% since 1990, while DALYs from Household air pollution in solid fuels decreased by 1.4%. …”

Supplementary file 1_Exploring the prevalence and risk factors of peripheral artery disease in patients with type 2 diabetes in sub-Saharan Africa: a systematic review and meta-ana... by Kirubel Eshetu Haile (13891134)

“…</p>Results<p>This study revealed that the pooled prevalence of PAD among patients with T2DM was 35.7% [95% confidence interval (CI) 28.7, 42.7], reflecting the significant impact of DM on vascular health with statistically significant heterogeneity observed between studies (I² = 94.9%, p < 0.001). …”

Cross-correlation between air pollutant types and AMD in different localities. by Alon Sela (12231559)