Data Sheet 1_Changes in voxel-wise gray matter asymmetry over time.pdf by Florian Kurth (350282)

“…Overall, decreases in asymmetry were more prominent than increases, but with hemisphere-specific effects (i.e., leftward asymmetries decreased more than increased, while rightward asymmetries increased more than decreased). …”

Data Sheet 1_Immunotherapy for neuromyelitis optica spectrum disorder: a comparative analysis of efficacy and safety of azathioprine, mycophenolate mofetil, tacrolimus, and rituxim... by Jing Zhou (168494)

“…The annual relapse rate (ARR) significantly decreased after treatment with all four drugs. …”

Supplementary Material for: Anti-Vascular Endothelial Growth Factor Treatment Outcomes in Macular Telangiectasia: A Systematic Review by figshare admin karger (2628495)

“…No study documented any significant adverse effects with treatment. Conclusion: Anti-VEGF agents may be associated with favourable anatomical and functional outcomes, particularly in proliferative MacTel, however, future large-scale clinical trials are warranted.…”

Data Sheet 1_Successional patterns of microbial communities across various stages of leaf litter decomposition in poplar plantations.pdf by Shuang Hu (182425)

“…With the decomposition of leaf litter, the total N content increased gradually, while other nutrients (C, P, K, cellulose and hemicellulose) decreased progressively. Litter characteristics had significant effects on microbial community structure: C/N, TK and residual hemicellulose (RH) were the primary driving factors affecting fungal community structure, whereas bacterial community structure was influenced by TK, RH, residual cellulose (RC) and lignin contents.…”

Data Sheet 1_Quantitative analysis of the caloric restriction versus isocaloric diets models based on macronutrients composition: impacts on body weight regulation, anthropometric,... by Denisa Pescari (20420147)

“…Isocaloric diets with varied macronutrient distributions showed significant weight loss compared to LED (p < 0.001). …”

Supplementary file 1_Harnessing functional feed additives for sustainable production: the role of Bacillus coagulans and Paenibacillus polymyxa mixture in improving production and... by Fayiz M. Reda (22300768)

“…Furthermore, the digestive enzymes were significantly (P < 0.05) improved, and the total bacterial and lactic acid bacteria counts were significantly (P < 0.05) augmented, whereas the counts of Salmonella spp., Escherichia coli, total coliform, and Enterococcus spp. were significantly (P < 0.05) decreased with dietary bacterial mixture treatments.…”

DataSheet2_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.pdf by Xiaoqin Zhang (517854)

“…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …”

Table 1_Lyophyllum decastes-derived polysaccharides alleviate DSS-induced colitis in mice by suppressing inflammation, enhancing intestinal barrier integrity, and restoring gut mic... by Eslam Ghaleb (21698810)

“…Additionally, LDP improved intestinal barrier function by reducing MPO activity and enhancing occludin and ZO-1 expression. 16S rRNA sequencing revealed a significant restoration of gut microbiota diversity, with an increase in beneficial bacteria Muribaculaceae, Lactobacillus, and Lachnospiraceae, and a reduction in pathogenic bacteria Escherichia-Shigella. these findings suggest that LDP exhibits therapeutic effects in DSS-induced colitis through anti-inflammatory properties, enhancement of intestinal barrier function, and modulation of gut microbiota. …”

DataSheet3_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.pdf by Xiaoqin Zhang (517854)

“…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …”

Table1_Myocardial infarction in rats was alleviated by MSCs derived from the maternal segment of the human umbilical cord.DOCX by Shuifen Sun (19855329)

“…Mechanistic experiments revealed that maternal-MSCs exerted cardioprotective effects by decreasing cardiomyocyte apoptosis, and promoting angiogenesis.…”

Image 1_Metformin enhances alpelisib sensitivity in HER2+ breast cancer by suppressing cancer stemness and oncogenic signaling.tif by Yujie Shi (737203)

“…Metformin enhanced these effects, demonstrating strong synergism. Combination treatment induced significant G0/G1 cell-cycle arrest, reduced ALDH1⁺ populations, and decreased tumorsphere formation. …”

Table 2_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx by Jian-Tong (21583487)

“…The combined pathway alterations in the D1 group increased inflammation, leading to elevated NF-κB expression, Kupffer cell polarization to M1, and lipid peroxidation, with n-6 PUFA interacting with choline deficiency to exacerbate these effects. Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …”

Data Sheet 1_RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.pdf by Ye Li (290115)

“…Purpose<p>Retinoblastoma is the most common intraocular cancer in infants and children, with a significant potential for metastasis. The mini-peptide ribosomal protein L41 (RPL41) has demonstrated extensive antitumor effects in vitro by promoting the degradation of activating transcription factor 4 (ATF4). …”

DataSheet1_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.docx by Xiaoqin Zhang (517854)

“…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …”

Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx by Jian-Tong (21583487)

“…The combined pathway alterations in the D1 group increased inflammation, leading to elevated NF-κB expression, Kupffer cell polarization to M1, and lipid peroxidation, with n-6 PUFA interacting with choline deficiency to exacerbate these effects. Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …”

Climate is more influential to vegetation green-up than factors that contribute to erosion following high-severity wildfire by Joseph Crockett (22077659)

“…In <a>highly erodible</a> scenarios, when accounting for growing season climate, coefficient of variation for year-of-fire precipitation, total precipitation, and soil erodibility decreased greenness in the fifth year. While the effects of year-of-fire factors related to erosion were significant, they were small, and the variability explained by growing season vapor pressure deficit and growing season precipitation were significantly greater.…”

Table 1_RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.xlsx by Ye Li (290115)

“…Purpose<p>Retinoblastoma is the most common intraocular cancer in infants and children, with a significant potential for metastasis. The mini-peptide ribosomal protein L41 (RPL41) has demonstrated extensive antitumor effects in vitro by promoting the degradation of activating transcription factor 4 (ATF4). …”

Data Sheet 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.pdf by Evan Fuini (21224939)

“…Treatment with psilocybin resulted in a significant dose-dependent increase in positive BOLD signal. …”

Data Sheet 2_Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.pdf by Samira Rastgoo (15252703)

“…</p>Results<p>After the intervention, supplementation with D5N and D5 significantly downregulated p16, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) expression and decreased SA-β-gal activity compared to the D1 group. …”

Data Sheet 2_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.xlsx by Alexandra Prodea (22617710)

“…We also searched for possible sources of heterogeneity in the studies assessed by analyzing several subgroups, which provided valuable information. They exerted their effect through various mechanisms such as apoptosis induction, metastasis and angiogenesis inhibition and decreased several cancer biomarkers such as ki-67, proliferating cell nuclear antigen (PCNA) and matrix metalloproteinases (MMP). …”