DataSheet1_Associations of thyroid hormones with chronic diarrhea and constipation in euthyroid individuals.docx by Weiwei Zeng (347272)

“…Multivariate linear regression analysis revealed a significant positive correlation between FT3 concentrations and the number of bowel movements [0.84 (0.39, 1.28), P<0.001]. …”

Data Sheet 1_Global prevalence of preeclampsia, eclampsia, and HELLP syndrome: a systematic review and meta-analysis.pdf by Víctor Juan Vera-Ponce (13207446)

“…Marked regional disparities were identified, with higher prevalences in low-income countries. Meta-regression for preeclampsia revealed a non-significant increasing trend over time (p = 0.23) and a significant inverse correlation with sample size (p < 0.01). …”

Cows' BHB impacts on calf BAT growth and metabolic health by Yanting Chen (20532152)

“…The results showed that although high BHB levels had no effect on calf birth weight or growth, they significantly impaired glucose sensitivity, increased stress genes and decreased brown adipose tissue mass, thermogenic proteins and mitochondrial density. …”

Ventromedial PFC pattern-separates cue-task associations. by Guochun Yang (1329693)

“…Data used for (B) can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002987#pbio.3002987.s010" target="_blank">S1 Data</a>, specifically in the sheet labeled “Fig 7B.” (C) The significant pattern separation effect (i.e., the negative coefficient, indicated by the red dashed line) compared with a null distribution obtained by randomly shuffling the transition point 5,000 times.…”

Supplementary file 1_Exploring the mediating factors linking adverse childhood experiences to traditional Chinese quality of life among older adults: a multi-factorial analysis.doc... by Mingjun Sun (532482)

“…High levels of perceived social support were identified as a protective factor, effectively mitigating the adverse effects of ACEs on CMQL among older adults individuals.…”

Supplementary Material for: Mapping Disease Burden of Major Depressive Disorder and Its Risk Factors in Low- and Middle-Income Countries by figshare admin karger (2628495)

“…The significant increase in MDD burden across all income groups after 2019 likely reflects the intensifying effects of global disruptions, with the COVID-19 pandemic being a key contributing factor. …”

Table_1_New insights into the increased risk of migraines from COVID-19 infection and vaccination: a Mendelian randomization study.DOCX by Jin Yang (86490)

“…We employed inverse variance weighted (IVW) fixed-effect and random-effect models as the primary methods for MR analysis, with MR-Egger and other approaches as complementary methods. …”

Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”

DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer... by Huijing Ren (19986303)

“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”

Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”

DMSO reduction in response to high irradiance exposure from simulated vertical mixing. by Brandon J. McNabb (19337538)

“…<b>(B, C)</b> Changes in maximum photosynthetic efficiency (F_v/F_m, n = 3) under LL and HL exposure for stations LBP8 and SS2, respectively. Significant simple main effects between treatments were found for SS2 (two-way mixed effects ANOVA model; ***: p < 0.001). …”

Image 1_White matter microstructure in mid- to late adulthood is influenced by pathway-stratified polygenic risk for Alzheimer’s disease.tiff by Judith R. Harrison (13922167)

“…</p>Results<p>In UK Biobank, higher PRS for protein–lipid complex assembly and tau protein binding were robustly associated with lower fractional anisotropy and higher mean diffusivity in both dorsal and parahippocampal cingulum segments (False discovery rate-corrected p < 0.05), explaining more variance than APOE alone; no significant effects emerged in the fornix. Genome-wide PRS showed weaker, non-significant associations. …”

Data Sheet 1_Associations between T-cell traits and narcolepsy type 1: new insights from a Mendelian randomization study.docx by Shiqin Chen (16719652)

“…Inverse variance weighted, Wald ratio, weighted median, and MR-Egger regression methods were used for the MR analysis. Odds ratios (ORs) were calculated, and heterogeneity tests, as well as pleiotropy tests, were conducted.…”

Supplementary Material for: Investigating the impact of screen-sharing visual aids during genomic results disclosure via telehealth in diverse families in the TeleKidSeq pilot stud... by Odgis J.A. (20574308)

“…Spanish- or English-speaking parents/legal guardians completed surveys at three timepoints to assess perceived and objective understanding, perceived confidence, and telehealth experience. Regression models evaluated the effect of screen-sharing over time. …”

Table 1_Associations between T-cell traits and narcolepsy type 1: new insights from a Mendelian randomization study.xlsx by Shiqin Chen (16719652)

“…Inverse variance weighted, Wald ratio, weighted median, and MR-Egger regression methods were used for the MR analysis. Odds ratios (ORs) were calculated, and heterogeneity tests, as well as pleiotropy tests, were conducted.…”

Table 1_White matter microstructure in mid- to late adulthood is influenced by pathway-stratified polygenic risk for Alzheimer’s disease.xlsx by Judith R. Harrison (13922167)

“…</p>Results<p>In UK Biobank, higher PRS for protein–lipid complex assembly and tau protein binding were robustly associated with lower fractional anisotropy and higher mean diffusivity in both dorsal and parahippocampal cingulum segments (False discovery rate-corrected p < 0.05), explaining more variance than APOE alone; no significant effects emerged in the fornix. Genome-wide PRS showed weaker, non-significant associations. …”

Data Sheet 1_A global synthesis of genotypic variation in crop greenhouse gas emissions under variable nitrogen fertilisation.docx by Conor Walthall (22301935)

“…To test the influence of genotype, we removed measurements from genotypes with fewer than three independent replicates (n = 97) and apply linear mixed-effects models to control for study and latitude effects. …”

Supplementary file 1_Interpretable machine learning for precision cognitive aging.docx by Abdoul Jalil Djiberou Mahamadou (21373586)

“…Notably, EBM highlights variations in how lifestyle activities impact cognitive performance, particularly differences between engaging in and refraining from specific activities, challenging regression-based assumptions. Moreover, our results show that the effects of lifestyle factors are heterogeneous across cognitive groups, with some individuals demonstrating significant cognitive changes while others remain resilient to these influences.…”

Table 1_Association of exposure to multiple volatile organic compounds with ultrasound-defined hepatic steatosis and fibrosis in the adult US population: NHANES 2017–2020.docx by Wentao Shao (11493004)

“…BKMR analysis identified a significant positive joint effect of VOC biomarkers on CAP. …”

Table 1_Healthy Eating Index-2020 and bowel habits: a cross-sectional analysis of NHANES.docx by Rongpeng Chen (21535799)

“…Subgroup analysis indicated that higher HEI-2020 scores were more strongly associated with a reduced constipation risk in participants with sleep disorders. WQS regression revealed significant protective effects of HEI-2020 scores on fecal incontinence and constipation, but not on diarrhea.…”