يعرض 20,501 - 20,520 نتائج من 21,342 نتيجة بحث عن '(( significant ((fold decrease) OR (a decrease)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.48s تنقيح النتائج
  1. 20501

    Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx حسب Jikai He (11888466)

    منشور في 2025
    "…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"
  2. 20502

    Exogenous jasmonic acid alleviates Cu-induced damages in guinea grass by enhancing photosynthesis, antioxidant enzyme activity and modifying associated metabolites حسب Jian Ren (175424)

    منشور في 2025
    "…The results indicated that Cu stress significantly reduced superoxide dismutase (−51.2%) and peroxidase (−38.0%), chlorophyll content, net photosynthetic rate (<i>Pn</i>), and led to decreases in leaf length, width, plant height, and biomass (−49.7%). …"
  3. 20503

    H2AK119ub is bidirectionally dynamic within cis-regulatory elements during neurodevelopment. حسب Aditya Parmar (22331873)

    منشور في 2025
    "…<b>(B)</b> Volcano plot depicting H2AK119ub abundance, as detected in normalized CUT&RUN data from early and late cerebellum, within SEACR-defined consensus peak regions. The significance threshold was a false-discovery rate <0.05, as defined by DiffBind [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref065" target="_blank">65</a>] (n = 4). …"
  4. 20504

    Table 1_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx حسب Qiqi Wu (4895728)

    منشور في 2025
    "…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …"
  5. 20505

    Table 1_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx حسب Chuanchuan Wang (12228518)

    منشور في 2024
    "…Linkage disequilibrium analysis showed that 2 SNPs of SPP1 (g. 36,700,265 C > T and g. 36,693,596 C > A) constituted a haplotype that correlated with milk protein percentage, and the dominant haplotype was H2H2, which was CCTT. 4 SNPs of NCAPG (g. 37,342,705 C > A, g. 37,343,379 G > T, g. 37,374,314 C > A and g. 37,377,857 G > A) constituted a haplotype associated with milk protein percentage, 305-days milk protein yield and 305 days milk yield. …"
  6. 20506

    Table 6_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx حسب Chuanchuan Wang (12228518)

    منشور في 2024
    "…Linkage disequilibrium analysis showed that 2 SNPs of SPP1 (g. 36,700,265 C > T and g. 36,693,596 C > A) constituted a haplotype that correlated with milk protein percentage, and the dominant haplotype was H2H2, which was CCTT. 4 SNPs of NCAPG (g. 37,342,705 C > A, g. 37,343,379 G > T, g. 37,374,314 C > A and g. 37,377,857 G > A) constituted a haplotype associated with milk protein percentage, 305-days milk protein yield and 305 days milk yield. …"
  7. 20507

    Table 3_Patient-needs-enhanced emergency nursing assessment framework accelerates time-critical care for non-traumatic chest pain.docx حسب Yan Sun (22436)

    منشور في 2025
    "…</p>Conclusions<p>Augmenting ENAF with a structured clinical-needs module significantly accelerates ECG acquisition, improves other process metrics and enhances nursing documentation while maintaining patient safety. …"
  8. 20508

    Table 2_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx حسب Chuanchuan Wang (12228518)

    منشور في 2024
    "…Linkage disequilibrium analysis showed that 2 SNPs of SPP1 (g. 36,700,265 C > T and g. 36,693,596 C > A) constituted a haplotype that correlated with milk protein percentage, and the dominant haplotype was H2H2, which was CCTT. 4 SNPs of NCAPG (g. 37,342,705 C > A, g. 37,343,379 G > T, g. 37,374,314 C > A and g. 37,377,857 G > A) constituted a haplotype associated with milk protein percentage, 305-days milk protein yield and 305 days milk yield. …"
  9. 20509

    Table 1_Patient-needs-enhanced emergency nursing assessment framework accelerates time-critical care for non-traumatic chest pain.docx حسب Yan Sun (22436)

    منشور في 2025
    "…</p>Conclusions<p>Augmenting ENAF with a structured clinical-needs module significantly accelerates ECG acquisition, improves other process metrics and enhances nursing documentation while maintaining patient safety. …"
  10. 20510

    Table 2_Patient-needs-enhanced emergency nursing assessment framework accelerates time-critical care for non-traumatic chest pain.docx حسب Yan Sun (22436)

    منشور في 2025
    "…</p>Conclusions<p>Augmenting ENAF with a structured clinical-needs module significantly accelerates ECG acquisition, improves other process metrics and enhances nursing documentation while maintaining patient safety. …"
  11. 20511

    Inflammatory markers correlate with lymphocytes infiltrating and predict immunotherapy prognosis for esophageal cancer حسب Bei Wang (116772)

    منشور في 2024
    "…</p> <p><b>Results:</b> Decreased inflammation was found to be associated with increased CD3<sup>+</sup> and CD8<sup>+</sup> T-cell infiltration and a better prognosis. …"
  12. 20512

    Table 3_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx حسب Chuanchuan Wang (12228518)

    منشور في 2024
    "…Linkage disequilibrium analysis showed that 2 SNPs of SPP1 (g. 36,700,265 C > T and g. 36,693,596 C > A) constituted a haplotype that correlated with milk protein percentage, and the dominant haplotype was H2H2, which was CCTT. 4 SNPs of NCAPG (g. 37,342,705 C > A, g. 37,343,379 G > T, g. 37,374,314 C > A and g. 37,377,857 G > A) constituted a haplotype associated with milk protein percentage, 305-days milk protein yield and 305 days milk yield. …"
  13. 20513

    Table 2_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx حسب Qiqi Wu (4895728)

    منشور في 2025
    "…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …"
  14. 20514

    Table 4_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx حسب Chuanchuan Wang (12228518)

    منشور في 2024
    "…Linkage disequilibrium analysis showed that 2 SNPs of SPP1 (g. 36,700,265 C > T and g. 36,693,596 C > A) constituted a haplotype that correlated with milk protein percentage, and the dominant haplotype was H2H2, which was CCTT. 4 SNPs of NCAPG (g. 37,342,705 C > A, g. 37,343,379 G > T, g. 37,374,314 C > A and g. 37,377,857 G > A) constituted a haplotype associated with milk protein percentage, 305-days milk protein yield and 305 days milk yield. …"
  15. 20515

    Supplementary Material for: ACOT4 and ACOT6 activate Akt-mTOR pathway and inhibit calcium oxalate-induced renal tubular cell injury حسب figshare admin karger (2628495)

    منشور في 2025
    "…Introduction: Kidney stones caused by calcium oxalate (CaOx) is a chronic kidney disease. Acyl coenzyme A thioesterases (ACOTs) serve as the key regulators of fatty acids metabolism. …"
  16. 20516

    Table 1_Jing-Yin-Gu-Biao formula protects mice from postinfluenza Staphylococcus aureus infection by ameliorating acute lung injury and improving hypercoagulable state via inhibiti... حسب Biao Lei (3763393)

    منشور في 2025
    "…Meanwhile, JYGBF inhibited the formation of neutrophil extracellular traps (NETs) in lungs, which is characterized by the production of ROS, peptidyl arginine deiminase 4 (PAD4), citrullinated histone H3 (CitH3), myeloperoxidase (MPO), neutrophil elastase (NE), S100A8/A9 and MPO-CitH3 colocalization. Moreover, JYGBF decreased platelet counts and the expression of its activated markers (CD62P and αIIbβ3) accompanied by the drop of fibrinogen (FIB) and fibrin degradation product (FDP), accounting for alleviating hypercoagulable state. …"
  17. 20517

    Data Sheet 1_Jing-Yin-Gu-Biao formula protects mice from postinfluenza Staphylococcus aureus infection by ameliorating acute lung injury and improving hypercoagulable state via inh... حسب Biao Lei (3763393)

    منشور في 2025
    "…Meanwhile, JYGBF inhibited the formation of neutrophil extracellular traps (NETs) in lungs, which is characterized by the production of ROS, peptidyl arginine deiminase 4 (PAD4), citrullinated histone H3 (CitH3), myeloperoxidase (MPO), neutrophil elastase (NE), S100A8/A9 and MPO-CitH3 colocalization. Moreover, JYGBF decreased platelet counts and the expression of its activated markers (CD62P and αIIbβ3) accompanied by the drop of fibrinogen (FIB) and fibrin degradation product (FDP), accounting for alleviating hypercoagulable state. …"
  18. 20518

    Table 5_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx حسب Chuanchuan Wang (12228518)

    منشور في 2024
    "…Linkage disequilibrium analysis showed that 2 SNPs of SPP1 (g. 36,700,265 C > T and g. 36,693,596 C > A) constituted a haplotype that correlated with milk protein percentage, and the dominant haplotype was H2H2, which was CCTT. 4 SNPs of NCAPG (g. 37,342,705 C > A, g. 37,343,379 G > T, g. 37,374,314 C > A and g. 37,377,857 G > A) constituted a haplotype associated with milk protein percentage, 305-days milk protein yield and 305 days milk yield. …"
  19. 20519

    Changes in dorsal-ventral patterning of CA1 in COUP-TFI mutant hippocampus. حسب Ching-San Tseng (6252566)

    منشور في 2025
    "…The Dcn/Wfs1 ratio was significantly decreased in the cKO and increased in the cTG. …"
  20. 20520

    Characterisation of conidial length and ascospore production in <i>ΔFgknr4</i> and complemented strains. حسب Erika Kroll (20537020)

    منشور في 2025
    "…<p><b>A.</b> Decreased conidial length observed in <i>ΔFgknr4</i>. …"