Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems by Local Burden of Disease HIV Collaborators (13279180)

“…</p><h3>Results</h3><p dir="ltr">All countries displayed over a 40-fold difference in HIV mortality between municipalities with the highest and lowest age-standardized HIV mortality rate in the last year of study for men, and over a 20-fold difference for women. …”

Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study by Shubham Chauhan (21334742)

“…</p><h3>Results</h3><p dir="ltr">A slight decrease in incidence rates from 80.57 to 79 per 100,000 was observed, alongside a significant increase in mortality rates from 14.11 to 17.2 per 100,000. …”

Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation by Larissa Haertle (3864310)

“…Performing a targeted association analysis for the significant T21-associated CpG sites in the AgeCoDe cohort, we found that 9 showed significant methylation differences related to AD dementia, including one in the ADAM10 gene. …”

DeepRaman: Implementing surface-enhanced Raman scattering together with cutting-edge machine learning for the differentiation and classification of bacterial endotoxins by Samir Brahim, Belhaouari

“…Unlike standard machine learning approaches such as PCA, LDA, SVM, RF, GBM etc, DeepRaman functions independently, requiring no human interaction, and can be used to much smaller datasets than traditional CNNs. …”
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

“…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …”
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Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis by Jabbour, Jana

“…WC was lower with all diets compared to UD, with no significant difference across specific diets. There was no significant interaction of the results with the pre-specified sub-groups. …”
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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…Addition of N-acetyl-cysteine (NAC); being a reactive oxygen species (ROS) scavenger, led to a significant decrease in the cytotoxicity of arginine deprivation to U251 and A172 cells, indicating that ROS generation reversed the cytotoxicity of arginine deprivation to GBM cells. …”
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Prevalence of Blastocystis sp. and other gastrointestinal pathogens among diarrheic COVID-19 patients in Italy by Marianna, Marangi

“…BackgroundGastrointestinal pathogens (GPs) contribute significantly to the burden of illness worldwide with diarrhoea being the most common among gastrointestinal symptoms (GSs). …”
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Prevalence and genetic diversity of Blastocystis sp. among autochthonous and immigrant patients in Italy by Marianna, Marangi

“…Out of the 927 investigated patients, 36 (3.9%) were positive for Blastocystis sp. A statistically significant association with African origin and age classes >18 years old was found. …”
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Proteomic insight towards key modulating proteins regulated by the aryl hydrocarbon receptor involved in ovarian carcinogenesis and chemoresistance by Lubna Therachiyil (4246156)

“…Our results showed that upon AhR activation by TCDD, out of 2598 proteins identified, 795 proteins were upregulated, and 611 were downregulated. STRING interaction analysis and KEGG-Reactome pathway analysis approaches identified several significantly dysregulated proteins that were categorized to be involved in chemoresistance, cancer progression, invasion and metastasis, apoptosis, survival, and prognosis in OC. …”

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... by Samar, Shurbaji

“…BackgroundIn the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. …”
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

“…</p><h3>Results</h3><p dir="ltr">Treatment of human breast cancer cells with increasing concentrations of VCX caused a significant decrease in cells growth and proliferation. …”

Transcriptomic profiling and bioinformatics-driven statistical prioritization of CRC biomarkers: A step toward precision oncology by Rawdhah M. Saleh (21436001)

“…<h3>Background</h3><p dir="ltr">Colorectal adenocarcinoma (COAD) is among the most common causes of cancer-related death globally. Early detection and targeted therapy depend on identifying key molecular biomarkers that drive tumor progression. …”

A GHRHR founder mutation causes isolated growth hormone deficiency type IV in a consanguineous Pakistani family by Safeer Ahmad (9079257)

“…Based on the current study, early detection of GHRHR may help in better therapeutic intervention.…”

Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

“…However, sunitinib did not induce apoptosis in either cell line at any time point, indicating that the anti-migratory effects of sunitinib were not due to impeding cell survival. …”
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Coevolving residues distant from the ligand binding site are involved in GAF domain function by Wesam S. Ahmed (10170053)

“…Statistical Coupling Analysis (SCA) of GAF domain sequences identified these residues, and molecular dynamics (MD) simulations of both apo and holo forms of wild-type and mutant (L267A, F295A) PDE5 GAFa domains revealed significant changes in structural dynamics and cGMP interaction. …”

The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis by Hoda Gad (6470522)

“…</p><h3>Conclusions</h3><p dir="ltr">This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. …”

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... by Samar Shurbaji (9938696)

“…<h3>Background </h3><p dir="ltr">In the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. …”

Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub... by SUGATHAN, SANAL

“…The outcome of these events, abundant regional solar irradiation and drop in global PV prices has led to the significant developments and innovations in the solar energy sector. …”
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Effect of Flexural NSM-FRP Bars on the Shear Strength of Reinforced Concrete Beams by Saleh, Rayyan Bashar

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