Showing 20,161 - 20,180 results of 23,096 for search '(( significant ((fold increase) OR (a decrease)) ) OR ( significant decrease decrease ))', query time: 0.51s Refine Results
  1. 20161

    Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

    Published 2025
    “…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
  2. 20162

    Supplementary file 1_Exploration of the renoprotective effect of Yi-Shen-Hua-Shi granules on db/db mice and the mechanism of podocyte apoptosis based on the GRP78/CHOP signaling pa... by Yanmo Cai (22235563)

    Published 2025
    “…</p>Results<p>YSHS significantly improved the general status of db/db mice, with a significant reduction in body mass, renal function indices, total cholesterol, triglycerides, and low-density lipoprotein. …”
  3. 20163

    Data Sheet 1_The role of oxidative stress in modulating mortality risk across the hypertension control cascade.docx by Weihao Liu (4472227)

    Published 2025
    “…Q1, HR: 0.82; 95% CI: 0.66–0.87; P < 0.001). A significant interaction was observed between OBS and hypertension control status (P for interaction = 0.017 and 0.026), corroborated by sensitivity analyses (P for interaction = 0.025). …”
  4. 20164

    Table 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx by Fuxing Lin (7418234)

    Published 2025
    “…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
  5. 20165

    Data Sheet 1_The MTNR1B Rs724030 variant is associated with islet function and women waist-to-hip ratio in healthy subjects.pdf by Sijie Zhang (7429373)

    Published 2025
    “…All these findings provide a basis for accurately assessing islet function in healthy populations and offer a new perspective on precision prevention.…”
  6. 20166

    Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf by Ying Xiao (6517)

    Published 2025
    “…Background<p>Pediatric infective endocarditis (IE) remains a rare but life-threatening condition, with substantial morbidity and mortality among children worldwide. …”
  7. 20167

    DataSheet1_Effects of inulin-type oligosaccharides (JSO) from Cichorium intybus L. on behavioral deficits induced by chronic restraint stress in mice and associated molecular alter... by Caihong Yao (15344128)

    Published 2024
    “…<p>Depression and anxiety are serious psychiatric disorders with significant physical and mental health impacts, necessitating the development of safe and effective treatments. …”
  8. 20168

    Data Sheet 1_Altered immune cell profiles in blood of mature/peripheral T-cell leukemia/lymphoma patients: an EuroFlow study.docx by F. Javier Morán-Plata (18986483)

    Published 2025
    “…Further dissection of the normal T-cell compartment showed a significant reduction of the earliest T-cell maturation compartments (N/CM) in T-PLL and SS/MF, whereas T-cells remained within normal ranges in T-LGLL, with only a minor reduction of N/CM T-cells.…”
  9. 20169

    Image 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif by Fuxing Lin (7418234)

    Published 2025
    “…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
  10. 20170

    Table 3_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

    Published 2025
    “…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
  11. 20171

    Image 1_Lower hippocampal volumes at baseline are associated with higher volume loss in healthy elderly.png by Vivian Schultz (17379235)

    Published 2025
    “…No covariates significantly influenced this association (p > 0.05).…”
  12. 20172

    Data Sheet 1_Association of cardiovascular health with COPD (NHANES 2007-2020): mediating potential of lean body mass.docx by Ruoyu Gou (11835929)

    Published 2025
    “…Background<p>Chronic Obstructive Pulmonary Disease (COPD) is a major global health concern, with lifestyle factors playing a crucial role in its prevention. …”
  13. 20173

    Table 1_Lactobacillus plantarum SAL delays aging-associated oxidative stress and gut microbiota dysbiosis in mice.doc by Wen Dong (467988)

    Published 2025
    “…</p>Methods<p>Twenty-four SPF KM male mice were divided into a control group (CON), model group (MOD), and a SAL strain intervention group (SAL). …”
  14. 20174

    Table 1_Trend analysis of pediatric urolithiasis prevalence from 1990 to 2021 in the BRICS.docx by Zhi-gang Zhang (328212)

    Published 2025
    “…Encouragingly, the Age-Standardized Prevalence Rate (ASPR) has shown a decreasing trend. The disease burden of pediatric urolithiasis is higher in India and Russia, with the prevalence in India and ASPR in Russia being the highest in the BRICS countries. …”
  15. 20175

    Table 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx by Fuxing Lin (7418234)

    Published 2025
    “…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
  16. 20176

    Data Sheet 1_Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in mice.pdf by Kaori Sakurai (1272567)

    Published 2025
    “…Introduction<p>Lung cancer is characterized by a poor prognosis and is a significant comorbidity of chronic obstructive pulmonary disease (COPD). …”
  17. 20177

    Data Sheet 1_Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.docx by Yuko Horikoshi (12202859)

    Published 2025
    “…Aims<p>Cardio-ankle vascular index (CAVI) is a non-invasive method for evaluating arterial stiffness. …”
  18. 20178

    Supplementary file 1_Effects of different urban vegetation cover and green space types on soil greenhouse gas emissions and carbon sequestration.docx by Ruisha Zhang (21287978)

    Published 2025
    “…<p>The development of urbanization has led to the creation of various types of green spaces, which have a direct influence on vegetation types and soil management, This, in turn, results in differences in soil carbon sequestration capacities. …”
  19. 20179

    Data Sheet 1_Impact of artificial intelligence on electronic health record-related burnouts among healthcare professionals: systematic review.pdf by Berna Sarraf (21651629)

    Published 2025
    “…Nevertheless, EHR-related workload has been considered as a significant contributor to healthcare professionals’ burnout, a syndrome associated with emotional exhaustion, depersonalization, and reduced personal accomplishment. …”
  20. 20180

    Table 7_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

    Published 2025
    “…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”