Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman, Alzu'bi

“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart by Amara, Issa E.A.

“…Moreover, Hg2+ significantly increased sEH protein expression and activity levels in hearts of mercury-treated mice, with a consequent decrease in 14,15-, and 11,12-epoxyeicosatrienoic acids (EETs) levels. …”
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High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury by Stanley, Ibeh

“…Also, cell proliferation post-TBI was repressed by HFD, which was accompanied by an increased lesion volume. SignificanceOur research indicated that chronic HFD feeding can worsen functional outcomes, predispose to neurodegeneration, and decrease brain recovery post-TBI. …”
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Novel Ternary Adder and Multiplier Designs without Using Decoders or Encoders by Aljaam J.M.

“…Extensive simulations (over 160) of the proposed designs in terms of PVT (Process, Voltage, Temperature) variations, noise effect, and scalability studies, along with several benchmark designs using HSPICE simulator, prove the significance of the proposed circuits to decrease the power-delay product (PDP), improve the robustness to process variations, and the noise tolerance. …”
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro by Rizk, Nasser Moustafa

“…In conclusion, this study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours, insulin could counteract the hyperglycemic effect on AKT/pI3 kinase which mediates NO production and VEGF-A, decreased adhesion molecules p-selectin involved in barrier disorder of retinal endothelial cells. …”
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A resource provisioning framework for bioinformatics applications in multi-cloud environments by Senturk, Izzet F.

“…The significant advancement in Next Generation Sequencing (NGS) have enabled the generation of several gigabytes of raw data in a single sequencing run. …”
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Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells by Alshwyeh, Hussah Abdullah

“…Furthermore, the extract exhibited higher toxicity towards NCI-H292 cells, followed by A549 and normal MRC-5 cells in decreasing order of potency. Our results suggest that the ethanolic extract of M. indica L. kernel has significant potential as a novel therapeutic agent for treating lung cancer cells, given its ability to induce apoptosis in cancer cell lines while causing minimal harm to normal cells.…”
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Bariatric Surgery Improves Serum CD40L Levels as a Predictor of Cardiovascular Risk: Systematic Review and Meta-analysis by Jamialahamdi, Tannaz

“…Random-effects meta-analysis of 7 studies including 191 subjects showed a significant reduction in CD40L after bariatric surgery (standardized mean difference (SMD), − 0.531; 95% CI, − 0.981, − 0.082; p = 0.021; I2, 87.00). …”
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Exploring the dynamics of algae-associated microbiome during the scale-up process of Tetraselmis sp. microalgae: A metagenomics approach by Hoda, Hosseini

“…Microbial profiling of each successive stage revealed lower abundance of eukaryotic organisms, whereas bacterial abundance increased notably resulting in a significant decrease in Tetraselmis sp. abundance. Furthermore, several bacteria with algae growth-promoting properties were found throughout the various culture stages including Balneola, Roseovarius, and Marinobacter. …”
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Growth and protein content of wheat kernels treated with three Growth regulators by Abo Hamed, S. A.

“…Alar, asulam or kinetin at different doses were sprayed on wheat plants and their effects on growth and protein of the developing kernels were investigated. …”
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25-Hydroxyvitamin D serum levels inversely correlate to disease severity and serum C-reactive protein levels in patients with hidradenitis suppurativa by Moltrasio, Chiara

“…Subsequently, Guillet et al.5 described an association between vitamin D deficiency and HS severity, also reporting a significant decrease of the inflammatory nodules in patients supplemented with vitamin D. …”
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Anaerobic and aerobic contributions to repeated supramaximal cycling exercises and their adaptation to high-intensity interval training in obese perimenopausal and postmenopausal w... by Jabbour, Georges

“…After HIIT, anaerobic contributions increased significantly in both groups (P < 0.01, respectively). …”
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Assessing Desalination Governance and the Promise of Technology in the Arabian Peninsula by Al-Saidi, Mohammad

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Changes in plant composition and diversity in an alpine heath and meadow after 18 years of experimental warming by Alatalo, Juha M.

“…Beta diversity increased in the meadow, while it decreased in the heath. Long-term warming had significant negative effects on the three orders of phylogenetic Hill diversity in the meadow. …”
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Rare case of norethisterone-induced hepatitis: A case report. by Arafa, Eiman A

“…Upon discontinuation of norethisterone, liver transaminases decreased to normal level within two weeks. Knowledge of rare adverse effects of drugs such as norethisterone is necessary for rapid identification and management, especially in patients with risk factors such as non-alcoholic liver disease and obesity.…”
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Variations in the temperature sensitivity of spring leaf phenology from 1978 to 2014 in Mudanjiang, China by Dai J.

“…The moving window analysis revealed that 75% of species displayed increasing ST of LUD, with 55% showing significant increases (P < 0.05). ST for the other 25% exhibited a decreasing trend, with 17% showing significant decreases (P < 0.05). …”
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Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways by El Hasasna, Hussain

“…Here, we investigated the effect of Rhus coriaria on the migration, invasion, metastasis and tumor growth of TNBC cells. …”
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Application of magnetic nanoparticles for the removal of oil from oil-in-water emulsion: Regeneration/reuse of spent particles by Elmobarak W.F.

“…A lower DMNP of 5 mg/L recovered up to 55.6% of the oil, while increasing the DMNP > 50 mg/L did not significantly affect the %ηdem nor the %Roil. The observed %Roil at a pH of 4 and Csur of 0.05 g/L was observed to be > 90 ± 0.1% and decreased by either rising the pH to 7 or increasing the Csur to 0.1 g/L. …”
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Artificial weathering and accelerated heat aging studies on low-density polyethylene (Ldpe) produced via autoclave and tubular process technologies by Luyt, A. S.

“…Accelerated (artificial) weathering and thermal aging tests were performed to investigate the effectiveness of different formulations in reducing the UV/heat degradation extent for two low-density polyethylene types (LDPE-A, LDPE-T). …”
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Dietary L-carnitine and vitamin-E; a strategy to combat ochratoxin-A induced immunosuppression by Bhatti S.A.

“…This study aimed to evaluate the effect of dietary ochratoxin A (OA), in the presence and absence of L-carnitine (LC) and vitamin E (VE), on the humoral immune responses of White Leghorn cockerels (WLC). …”
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