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significant genes » significant event (Expand Search), significant decrease (Expand Search)
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81
Non-steroidal anti-inflammatory drugs and bone healing in animal models-a systematic review and meta-analysis
Published 2021“…Conclusion: The findings demonstrated that NSAIDs administration decreased the biomechanical properties of healing bones after fracture surgery in comparison to the control group. …”
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82
Release of colloids in saturated porous media under transient hydro-chemical conditions: A pore-scale study
Published 2021“…The deposition and consequent release of colloids pose a significant challenge to the environment, groundwater quality and human health. …”
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83
A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis
Published 2022“…Since several transcriptome studies have shown a significantly decreased expression of DCD in HS skin, we hypothesised that the identified frameshift insertion was a loss-of-function mutation that might be associated with HS susceptibility in this family. …”
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84
EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS
Published 2016“…Results: We found that hyperglycemia increases the cellular production of reactive oxygen species (ROS) and PBA decreasing it. Also the barrier quality of HRMEC was affected significantly with treatment of high glucose and improved with PBA. …”
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85
Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway
Published 2023“…In vivo model, the oral administration of oleuropein at 50 mg/kg in rats fed with high fat diet for 8 weeks reduced inflammation in liver and adipose tissues (WAT), improved glucose intolerance, and decreased hyperinsulinemia. Furthermore, the immunohistochemistry revealed that the expression level of p-Akt, IRS1, and Glut-4 were significantly enhanced in liver and WAT tissues after oleuropein supplementation comparing with that in HFD group. …”
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86
Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse
Published 2016“…The groups treated with EGCG, phloretin and [6]-gingerol at 75 mg/kg significantly decreased blood sugar levels to 128 ± 8, 125 ± 15 and 132 ± 9 mg/dL, respectively. …”
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87
The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane
Published 2020“…Additionally, SFN treatment did not significantly change the expression of TBC1D4, and GLUT4 genes in skeletal muscles compared to vehicle treatment (p values >0.05). …”
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88
The Gender-Pay Gap and the Family in the Gulf: Root Causes, Implications and Policy Response
Published 2020“…According to evidence it decreases family incomes and increases poverty. Although, women contribute significantly to the family's economic well-being, they continue to earn less than their male colleagues. …”
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89
Energy depletion and opportunistic microbial colonisation in white syndrome lesions from corals across the Indo-Pacific
Published 2020“…Total lipid levels varied significantly among locations, though a consistent stepwise decrease from healthy tissues from healthy colonies (HH) to healthy tissue on WS-diseased colonies (HD; i.e. preceding the lesion boundary) to diseased tissue on diseased colonies (DD; i.e. lesion front) was observed, demonstrating a reduction in energy reserves. …”
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90
Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging mice
Published 2021“…Mice fed the iso-caloric diet supplemented with fish oil exhibited significantly higher levels of bone density in different regions compared to the other groups. …”
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91
Electrochemical and thermodynamic study on the corrosion performance of API X120 steel in 3.5% NaCl solution
Published 2020“…The overall results revealed that PEI significantly decreases the corrosion rate of API X120 steel with inhibition efficiency of 94% at a concentration of 100 μmol L−1. …”
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92
Profiling of intestinal microbiota in patients infected with respiratory influenza a and b viruses
Published 2021“…Notably, virus shedding in fecal samples of some patients had significantly reduced gut bacterial diversity (p = 0.023). …”
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93
Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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94
Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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95
Colloid retention and mobilization mechanisms under different physicochemical conditions in porous media: A micromodel study
Published 2021“…However, for hydrophobic colloids, changes in solution chemistry significantly increase colloid retention where the colloid interaction become attractive with the increase in ionic strength and decrease in pH values. …”
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96
DIFFERENTIAL EXPRESSION OF MICRORNAS BY ANTI-OBESITY TREATMENT SULFORAPHANE IN SKELETAL MUSCLE OF DIET-INDUCED OBESITY IN MICE
Published 2023“…Results: Body weight, food intake, plasma glucose, and leptin levels were significantly decreased in SFN-treated mice compared to control groups. …”
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97
The effect of triiodothyronine on maturation and differentiation of oligodendrocyte progenitor cells during remyelination following induced demyelination in male albino rat
Published 2016“…After one week of cuprizone withdrawal, PDGFRα positive cells and gene expression showed significant increase in +ve control and T3-treated groups as compared to −ve control with insignificant difference in between the former two groups. …”
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98
Prevention of oral cancer
Published 2017“…Current research also focuses on emerging gene therapy through employing adenoviruses. This chapter will address and focus on the aforementioned prevention strategies, elaborating and expanding on risk factors and how to decrease chances of developing oral cancer. …”
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99
Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation
Published 2016“…Biochars can also be custom-designed to increase/decrease native soil pH to bring it closer to the optimum range for microbial and plant growth. …”
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100
Screening of Qatari Microalgae and Cyanobacteria for Application in CO2 Utilization
Published 2018“…The most productive strain was Tetraselmis sp., with a maximum biomass productivity of 157.7 ± 10.9 mg L-1 d-1 at 30˚C, with a decreasing productivity for increasing temperatures. …”
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