Discovery of the First Highly Selective and Broadly Effective Macrocycle-Based Type II TRK Inhibitors that Overcome Clinically Acquired Resistance by Zuqin Wang (12422128)

“…Small-molecule macrocyclic kinase inhibitors have displayed significant advantages in overcoming clinical resistance driven by kinase mutations; however, all reported small-molecule macrocyclic TRK inhibitors are all type I inhibitors and are therefore much more sensitive to SF than xDFG mutations. …”

Overall survival of RAS-mutated metastatic colorectal cancer based on allele frequency. by Udit Nindra (17101646)

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Muscle attachments and force vectors for mandible and cranium. by Pranav N. Haravu (14043109)

Relative expression (fold-change) of immune genes in LPS-stimulated peritoneal macrophages. by Chaiwat Monmai (6377270)

Relative expression (fold-change) of immune genes in mitogen-stimulated splenic lymphocytes. by Chaiwat Monmai (6377270)

Kaplan-Meier Survival Curve of Forced Stop Duration. by Fangyi Yang (18867853)

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The experimental technology combining a fluid shear stress experimental system with Atomic Force Microscopy (AFM). by Xinyao Zhao (5824427)

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LPS up-regulated DEGs identified by RRA and fold-change analysis. by Giorgia Colombo (6337118)

Top significant associations between relevant binary disease phenotypes and ROMK variants in the UK Biobank. by Nga H. Nguyen (2075920)

The catalase enzyme response of <i>A</i>. <i>albopictus</i> larvae decreased (1.5-fold) in response to <i>M</i>. <i>robertsii</i>-derived copper nanoparticles. by Perumal Vivekanandhan (4863484)

Shearing forces in the tension zone. by Maogang Tian (21485116)

“…The outer ring of inclined piles in the VIPF significantly enhances structural stiffness through spatial synergy, achieving uniform load distribution and effective redistribution of pile-body internal forces. …”

Shearing force in the pressure zone. by Maogang Tian (21485116)

“…The outer ring of inclined piles in the VIPF significantly enhances structural stiffness through spatial synergy, achieving uniform load distribution and effective redistribution of pile-body internal forces. …”

Axial force in the pressure zone. by Maogang Tian (21485116)

“…The outer ring of inclined piles in the VIPF significantly enhances structural stiffness through spatial synergy, achieving uniform load distribution and effective redistribution of pile-body internal forces. …”

Axial forces in the tension zone. by Maogang Tian (21485116)

“…The outer ring of inclined piles in the VIPF significantly enhances structural stiffness through spatial synergy, achieving uniform load distribution and effective redistribution of pile-body internal forces. …”

Summary of sequenced AR mutations acquired in the secondary mutation library. by Haoran Zhang (731854)

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Involvement of POm increases as discriminability of texture stimuli decreases. by Jia Qi (400499)

The applied forces and moments. by Petr Boháč (20685499)

The fold change of the main metabolites in CHA, CHM, and MHE rats with P values and VIP score. by Xue-Fei Liu (11156387)

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

Average muscle forces during the stance phase of gait obtained from agonist and antagonist muscle groups. by Hans Kainz (8459514)

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