De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response. حسب Sarfraz Shafiq (13259589)

"…<p><b>(A)</b> Volcano plot of ATAC-seq results for sequence repeats with increased (blue) and decreased (red) chromatin accessibility in ATRX-null microglia. …"

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries حسب Xiyin Huang (11528200)

"…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …"

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries حسب Xiyin Huang (11528200)

"…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …"

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries حسب Xiyin Huang (11528200)

"…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …"

Experiment 3 –trial E. حسب Ottavia Benedicenti (9100619)

"…Violin plots show Cq median (solid line). Statistical significance levels were calculated with the GraphPad Prism v9.3.1 (* = p ≤ 0.05; n = 3).…"

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries حسب Xiyin Huang (11528200)

"…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …"

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries حسب Xiyin Huang (11528200)

"…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …"

Cytochrome bd-II oxidase CyxA promotes the pathogenicity of <i>Klebsiella pneumoniae</i> by resisting oxidative stress حسب Xiao Xiao (99147)

"…Additionally, the expression levels of <i>cyxA</i> at 37°C and 41°C were significantly higher compared to 30°C, and the Δ<i>cyxA</i> strain exhibited significantly lower viable counts, elevated intracellular reactive oxygen species (ROS) levels, and decreased total antioxidant capacity (T-AOC) relative to WT at 37°C and 41°C. …"

ABR wave I and IV parameters in response to clicks. حسب Carolin Jüchter (17384611)

"…The P1-N1 amplitude at 90 dB SPL (<b>A</b>) was significantly reduced two days post-trauma compared to pre-trauma and stayed decreased three weeks post-trauma. …"

Flow Chart of the Study Steps. حسب Azam Hosseinpour (13434515)

"…</p><p>Conclusion</p><p>The IP-GBL enhanced germane cognitive load and decreased the intrinsic and extrinsic cognitive load, which facilitated students’ learning. …"

Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy حسب Ya-yin Tan (21448519)

"…In experiments with SV40-transformed mouse glomerular mesangial cells (MCs), PCK1 and PPARγ protein expression levels were significantly decreased in polymeric IgA1 (pIgA1)-stimulated MCs, which contrasts with the increased expression of inflammatory and fibrotic factors. …"

Image 2_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif حسب Houle Guo (21264647)

"…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …"

Image 5_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf حسب Na He (295300)

"…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …"

Image 1_Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome.jpeg حسب Mailén Rojo (10802556)

"…</p>Results<p>Our findings showed that patients with PCOS had decreased mtDNA content and increased oxidation damage. …"

Data Sheet 1_Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes.docx حسب Michael Hesse (439701)

"…Background<p>Pregnancy significantly affects the maternal cardiovascular system, with physiological adaptations characterized by cardiac hypertrophy and increased capillarization. …"

Data Sheet 1_STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.pdf حسب Rongrong Huang (819212)

"…Symptoms of pneumonia in STING-KO mice infected with PR8 were significantly milder than those in WT mice, and NETs were less likely to form in the lung tissue of STING-KO mice. …"

Table 3_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx حسب Kaihao Lin (13016658)

"…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…"

Integrating legumes into cropping systems enhances soil carbon and nitrogen content while reduces the soil carbon-to-nitrogen ratio: A global meta-analysis حسب Zhiqiang Lu (20145192)

"…Moreover, SOC and STN increased when legumes replaced fallow or gramineous soil, whereas SCN significantly decreased only when legumes replaced gramineous systems. …"

Image 2_CT angiography-derived three-dimensional pulmonary vein topography is related to the outcome after cryoballoon ablation.tiff حسب Martin Saal (21267734)

"…The number of occlusion attempts in the right inferior PV was significantly higher in the PVI failure group indicating a technical more complex balloon occlusion. …"

DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx حسب Abdul Mateen (12055673)

"…Pharmacokinetic parameters such as AUC_0-t, C_max MRT, Vd, and half-life (t_1/2) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar^®). …"