The top 20 candidate drugs demonstrating the most significant sensitivity differences between high- and low-GSRS subjects. by Yu Zhang (12946)

Subjects:

NgR1 KO mice exhibited an increase in excitatory synapses and a decrease in inhibitory synapses, indicating an imbalance of synaptic transmission. by Jinwei Zhang (462455)

“…The inhibitory synaptic density of NgR1 mice showed a significant decrease when compared to WT mice (***P <  0.001). …”

Blending Bayesian and Classical Tools to Define Optimal Sample-Size-Dependent Significance Levels by Mark Andrew Gannon (6491468)

“…A testing procedure is developed using a mixture of frequentist and Bayesian tools, with a significance level that is a function of sample size, obtained from a generalized form of the Neyman–Pearson Lemma that minimizes a linear combination of <i>α</i>, the probability of rejecting a true null hypothesis, and <i>β</i>, the probability of failing to reject a false null, instead of fixing <i>α</i> and minimizing <i>β</i>. …”

The relative duration and distance in each time gap. by Tomohiro Gonjo (8825780)

Treatment with ICs causes a significant decrease in podocyte proliferation. by George Haddad (470789)

Risk of bias analysis using QUIPS tool for studies included in the meta-analysis. by Amit Kumar (81180)

Long COVID prevalence decreases with vaccine uptake in the U.S. by Manlio De Domenico (626037)

“…<p>(A) Prevalence in U.S. states and the U.S. exhibits a decreasing trend with respect to vaccine uptake, both in the population vaccinated with at least one dose (top) and two doses (bottom), with the largest gap between 100% vaccinated and 100% unvaccinated scenarios observed in the reference population of adults who had COVID-19. …”

AdMSC-EVs enhanced colony formation and migration of LECs and decreased proliferation. by Xiaoqin Li (1399105)

Full list of proteins significantly enriched by BioID2 labelling. by Jan Pyrih (229124)

“…Column M: the probability that a protein has the mitochondrial import signal detected with the Mitofates online prediction tool. Columns N and O display whether the protein was previously experimentally localized in the mitochondrion (TrypTag) or was present in the Tom40-based depletome. …”

Significant decrease of the viability of A375 melanoma cells after CD treatment. by Lena Berning (7430117)

Eight urinary metabolites exhibited significant changes in the MSG-treated groups at week 12, and MSG-withdrawal group at weeks 0, 4, 8, 10, and 12. by Manatsaphon Sukmak (19532771)

“…In contrast, three metabolites including methylamine (E), N-methyl-4-pyridone-3-carboxamide (F), and taurine (H) showed significant decreased after MSG consumption and elevated after MSG withdrawal. …”

AMP prediction tools employed in this study. by Allister Irvine (11232111)

Concentration of RebA and Steviol showed increased significantly, whereas stevioside showed significant decrease in all the transgenic lines. by Nazima Nasrullah (6874496)

“…<p>Concentration of RebA and Steviol showed increased significantly, whereas stevioside showed significant decrease in all the transgenic lines.…”

Significance values for enrichment analysis of tissue-specific eQTLs. by Merina Shrestha (2608627)

The number of gauging cross-sections where a statistically significant decreasing trend was identified. by Krzysztof Kochanek (835532)

“…<p>The number of gauging cross-sections where a statistically significant decreasing trend was identified.…”

Complete results of significance tests. by Tianqi Yang (9043082)

PointSite: A Point Cloud Segmentation Tool for Identification of Protein Ligand Binding Atoms by Xu Yan (110026)

“…With the fine-grained atom-level binding atoms representation and enhanced feature learning, PointSite can outperform previous methods in atom Intersection over Union (atom-IoU) by a large margin. Furthermore, our segmented binding atoms, that is, atoms with high probability predicted by our model can work as a filter on predictions achieved by previous pocket-centric approaches, which significantly decreases the false-positive of LBS candidates. …”

PointSite: A Point Cloud Segmentation Tool for Identification of Protein Ligand Binding Atoms by Xu Yan (110026)

“…With the fine-grained atom-level binding atoms representation and enhanced feature learning, PointSite can outperform previous methods in atom Intersection over Union (atom-IoU) by a large margin. Furthermore, our segmented binding atoms, that is, atoms with high probability predicted by our model can work as a filter on predictions achieved by previous pocket-centric approaches, which significantly decreases the false-positive of LBS candidates. …”

Significance of features. by Wei Yin (64393)

Discovery of Natural Products Alleviating Renal Fibrosis with a Viscosity-Responsive Molecular Probe by Kaiyu Zhang (198799)

Subjects: