Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”

Biomass gasification combined with a novel heat integration design for sustainable energy supply programs: Comprehensive thermodynamic, environmental, and economic evaluations by Fei Wang (19534)

“…<p dir="ltr">The development of sophisticated multi-generation solutions that can concurrently produce electricity, heating, cooling, and hydrogen is required due to the increasing demand for efficient and sustainable energy systems. …”

Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy by Nassiba Taib (14557385)

“…Interestingly, in the metastatic 1872 Col cells treated with DAC, the expression of both PD-L1 and NY-ESO-1 was increased tenfold (*p = 0.0128) and fivefold (***p < 0.0001), respectively.…”

Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy by Samson Mathews Samuel (18808246)

“…Additionally, treatment with metformin and 2DG (5 mM) inhibited the Akt/mTOR pathway and down-regulated the cell-cycle-related proteins such as p-cyclin B1 (S147) and cyclins D1 and D2 when compared to cells that were treated with either 2DG or metformin alone. Treatment with a combination of 2DG (5 mM) and metformin (2 mM) also significantly decreased cell proliferation, migration and tubulogenic capacity when compared to cells that were treated with either 2DG or metformin alone. …”

Optimal scheduling algorithm for residential building distributed energy source systems using Levy flight and chaos-assisted artificial rabbits optimizer by M. Premkumar (12757280)

“…<p>The increase in demand for MicroGrids (MGs) is a significant factor in the provision of electricity in the future, mainly due to the use of renewable energy sources, which reduces the release of hazardous gases. …”

Enhancing the quality of lentil proteins via combination with whey proteins based on a dual process: a novel strategy through the incorporation of complexation and fermentation by Mohammad Alrosan (20089263)

“…The FTIR spectrophotometer scans indicated significant (<i>P</i> < 0.05) changes to the secondary protein structure components (random coil and α-helix). …”

Co-production of high density biomass and high-value compounds via two-stage cultivation of Chlorella vulgaris using light intensity and a combination of salt stressors by Eman A. El-fayoumy (17788952)

“…Cultures supplemented with 5 g L⁻¹ NaCl / 5 g L⁻¹ MgCl₂ / 5 g L⁻¹ CaCl₂ and high light intensity exposure attained consistently high carbohydrate content (52.71 ± 2.50%). The combination of 7.5 g L⁻¹NaCl / 7.5 g L⁻¹MgCl₂ also resulted in a marked increase in the protein content (35.32 ± 2.20%) and total carotenoids (0.31 ± 0.03 μg mL⁻¹) as compared to the Controls. …”

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension by Thiruveni Ramkumar (17075051)

“…On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…”

Rescue cerclage by Khoury, Alfred

“…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …”
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STARD 13 in prostate cancer. (c2018) by Saab, Sahar S.

“…Proliferation and migration are known to be regulated by Rho family of GTPases. StarD13 is a GAP for Rho GTPases and has been previously described to be a tumor suppressor in astrocytoma, breast and colorectal cancer. …”
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Analyzing the effectiveness of various coatings to mitigate photovoltaic modules soiling in desert climate by Alaa Elsafi (22282354)

“…The results indicate a decrease in light transmittance and an increase in surface coverage area over time due to dust accumulation. …”

The Impact of Nutritional Supplementation During Pregnancy on the Incidence of Gestational Diabetes and Glycaemia Control by Ibrahim Ibrahim (673877)

“…The release of placental hormones during pregnancy induces/ increases maternal insulin resistance and promotes nutrition utilization by the fetus. …”

Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals by Angy, Mallah

“…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …”
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Recent advances in the treatment and outcome of locally advanced rectal cancer by Abdalla, Eddie

“…Results There were 219 patients in the early era and 109 in the late era. No significant differences were seen in patients (age, gender, race) or tumor characteristics (mean distance from the anal verge, annularity, fixation). …”
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Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained? by Wahiba Elhag (5245547)

“…Mean HbA1c significantly decreased from 8.1%preop to 6.77%_{year 9}. …”

Sex differences on quality of life and mental health outcomes when using a brief cognitive-behavioral skill building intervention with adolescent Syrian refugees: a secondary analy... by Kazandjian, Chant

“…Among males only, significant decreases in depression and anxiety scores were observed with significant improvement in total QOL.…”
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Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals by Angy Mallah (17831954)

“…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …”

Mitigation of Greenhouse Gas Emissions from Agricultural Fields through Bioresource Management by Rimsha Khan (17542128)

“…The objective of this study was to evaluate the role of organic amendments including biodigestate (BD), biochar (BC), and their combinations with inorganic fertilizer (IF) in increasing carbon sequestration potential and mitigation of GHG emissions from potato (Solanum tuberosum) fields. …”

Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries by Mouyad Alsamara (17823668)

“…These findings have significant implications for labor markets and nationalization policies in the GCC countries.…”

Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries by Mouyad, Alsamara

“…These findings have significant implications for labor markets and nationalization policies in the GCC countries.…”
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