Increased MicroRNA Levels in Women With Polycystic Ovarian Syndrome but Without Insulin Resistance: A Pilot Prospective Study by Alexandra E. Butler (6189536)

“…However, little is known about miRNA expression in women with PCOS who are not insulin resistant (IR).</p><h3>Methods</h3><p dir="ltr">Circulating miRNAs were measured using quantitative polymerase chain reaction (qPCR) in 24 non-obese BMI and age matched women with PCOS and 24 control women. …”

White spot lesions, plaque accumulation and salivary caries-associated bacteria in clear aligners compared to fixed orthodontic treatment. A systematic review and meta- analysis by Shailaja Raghavan (18001645)

“…The pooled results showed significantly lower plaque accumulation(SMD − 1.58;95%CI:-2.57,0.58;p = 0.002) in CA compared to CF appliances.…”

Efficacy and safety of ensifentrine, a novel phosphodiesterase 3 and 4 inhibitor, in chronic obstructive pulmonary disease: A systematic review and meta-analysis by Eeshal Fatima (18255772)

“…<h3>Background </h3><p dir="ltr">We evaluated the efficacy and safety of Ensifentrine in COPD via a systematic review and meta-analysis of randomized controlled trials (RCTs). </p><h3>Methods </h3><p dir="ltr">We performed a detailed literature search on Medline (via PubMed), Scopus, Google Scholar, and Cochrane on the basis of pre-specified eligibility criteria. …”

One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes by Goran Petrovski (129836)

“…</p> <h2>Methods</h2> <p>This was a 1-year observational study, as a continuation of the previous 3 months prospective study of pediatric patients with T1D conducted at Sidra Medicine in Qatar. …”

Patient-oriented educational Sports Medicine YouTube videos in Arabic have higher view counts in the Middle East and North Africa than their English versions by Theodorakys Marín Fermín (12199534)

“…Except for one, the view count was significantly higher in the Arabic version of all 11 videos (minimum sevenfold, P = 0.03). …”

Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4⁺CD25⁺Foxp3⁺ and CD4... by Magdalena J. Polanczyk (14153283)

“…In the current study, we evaluated the effect of SM16 on Treg generation and function. </p><h3>Methods</h3><p dir="ltr">Using BALB/c, FoxP3eGFP and Rag^−/− mice, we performed FACS analysis to determine if SM16 blocked de novo TGF-β-induced Treg generation in vitro and in vivo. …”

Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 diabetes mellitus by Asma A Elashi (18464133)

“…We aimed to define the genetic determinants of T2D in Qatar.</p><h3>Methods</h3><p dir="ltr">Using whole genome sequencing of 11,436 participants (2765 T2D cases and 8671 controls) from the population-based Qatar Biobank (QBB), we conducted a genome-wide association study (GWAS) of T2D with and without body mass index (BMI) adjustment.…”

Evaluation of psychological distress, burnout and structural empowerment status of healthcare workers during the outbreak of coronavirus disease (COVID-19): a cross-sectional quest... by Sara Taleb (11264352)

“…The main aim of this study was to assess the psychological distress, burnout and structural empowerment status of HCWs during the COVID-19 outbreak, and to evaluate its predictors.</p><h3>Methods</h3><p dir="ltr">This multi-center, cross-sectional web-based questionnaire survey was conducted on HCWs during the outbreak of COVID-19 from August 2020 to January 2021. …”

A GHRHR founder mutation causes isolated growth hormone deficiency type IV in a consanguineous Pakistani family by Safeer Ahmad (9079257)

“…<i>In-silico</i> and biochemical analyses support the pathogenic effect of this nonsense mutation, while our comprehensive phenotype and hormonal profiling has established the genotype–phenotype correlation. …”

Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson’s disease by Hidetomo Murakami (6105284)

“…Lower CSF levels of Aβ1–42, total tau and P-tau181p were significantly related to worsening of some motor and/or cognitive functions. …”

Causes of construction reworks and their mitigation strategies by HAYAT, KAMRAN

“…Later these factors will be analyzed to computer the significance and variance of independent factors on depend factors. …”
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