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Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
منشور في 2020"…Here, we used bisulfite pyrosequencing and show that methylation of the rDNA transcription unit including upstream control element (UCE), core promoter, 18S rDNA, and 28S rDNA in human sperm also significantly increases with donor's age. This positive correlation between sperm rDNA methylation and biological age is evolutionarily conserved among mammals with widely different life spans such as humans, marmoset, bovine, and mouse. …"
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Potential Medical Applications of Chitooligosaccharides
منشور في 2022"…COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these strategies. COS is of significant interest for pharmacological and medical applications due to its increased water solubility and non-toxicity, with a wide range of bioactivities, including antibacterial, anti-inflammatory, anti-obesity, neuroprotective, anticancer, and antioxidant effects. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …"
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The potential of technology in education. (c2016)
منشور في 2016احصل على النص الكامل
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Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines
منشور في 2018"…In conclusion, the Ru‐centered complex 1 could represent a potential photoactivatable chemotherapeutic drug that increases selectivity to tumors and offers alternative treatment in the light of increasing cisplatin resistance.…"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Harnessing Waste for Emission Cuts: the Anaerobic Digestion Potential in Qatar
منشور في 2025"…<p dir="ltr">The Gulf Cooperation Council (GCC) countries are on the verge of a significant shift in waste management, with governments increasingly focused on reforming the waste sector. …"
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Potential Biomarkers to Predict Acute Ischemic Stroke in Type 2 Diabetes
منشور في 2021"…PPBP and THBS1 tended to increase at hypoglycemia in both cohorts, though reached significance only in controls (p < 0.05), returning to BL levels post-hypoglycemia. …"
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Nuancing the double and triple nexus: analyzing the potential for unintended, negative consequences
منشور في 2023"…<p dir="ltr">International and national actors are increasingly calling for a double or triple nexus approach to humanitarian, development, and peace activities to improve the flexibility of programming, particularly in complex crises. …"
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Solving the Narrow Corridor Problem in Potential Field-Guided Autonomous Robots
منشور في 2005"…In addition to eliminating the narrow corridor artifact, improving the quality of the trajectory, the suggested solution significantly increases the speed of the robot. Theoretical development along with simulation results are provided.…"
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Numerical investigation of the potential of using hydrogen as an alternative fuel in an industrial burner
منشور في 2024"…Mass flow rate (MFR) adjustments and excess air variation significantly influenced emissions, with a 25% MFR increase reducing NOx to 2.8 × 10<sup>-5</sup>, while higher excess air (e.g.,30%) raised NO<sub>x</sub> under lean conditions. …"
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
منشور في 2021"…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …"
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Invasive Species as Rivals: Invasive Potential and Distribution Pattern of Xanthium strumarium L.
منشور في 2022"…<p dir="ltr">Xanthium strumarium L. is a globally successful invasive herb that has had significant negative ecological, economic and social impacts in many world regions. …"
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Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods
منشور في 2022"…Consequently, resistant pests reduce the yield of agricultural production, causing significant economic losses and reducing food security. …"
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Ecological impacts and potential hazards of nickel on soil microbes, plants, and human health
منشور في 2024"…It also argues that these measures are necessary in light of the increasing level of Ni pollution in soil ecosystems and the potential impacts on public health and the environment.…"
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