Data Sheet 3_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Development of guinea pig monaural auditory brainstem responses (ABRs). by Kelsey L. Anbuhl (22190594)

“…Click-ABR thresholds decrease significantly with age (Left correlation = −0.69, <i>p</i> < 0.001; Right correlation: −0.6, <i>p</i> < 0.001). …”

Data Sheet 4_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Table 1_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

Table 1_Global, regional, and national burden of atrial fibrillation/flutter attributable to metabolic, behavioral, and environmental risk factors, 1990–2021: a longitudinal observ... by Zhen Wei (203204)

“…Smoking showed the greatest decrease, with AAPCs of ASMR and ASDR at −0.66 (95% CI: −0.68 to −0.65) and −0.72 (95% CI: −0.72 to −0.71), most significantly in women aged 30–34. …”

Table 5_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Data Sheet 2_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Data Sheet 1_Enabling immune checkpoint blockade efficacy in T-lymphopenia by restoring CD8 T cell dynamics with IL-7 cytokine therapy.docx by Yeon-Woo Kang (18285202)

“…The combination of rhIL-7-hyFc and anti-PD-1 therapy resulted in significant tumor regression and improved mouse survival.…”

Data Sheet 1_Glucocorticoids and immunoglobulin alone or in combination in the treatment of multisystemic inflammatory syndrome in children: a systematic review and network meta-an... by Junjie Lin (8379594)

“…</p>Conclusions and relevance<p>GCs monotherapy significantly reduces treatment failure rates and persistent fever duration, while combination therapy significantly reduces the need for adjunctive immunotherapy. …”

Table 4_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Data Sheet 1_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

Rising mercury consumption from blue foods in China balanced by a shift to lower-mercury choices by Wendy Wang (19812924)

“…Results show that despite per capita THg consumption rose gradually due to rising blue food consumption, there was a national shift toward low-THg blue foods driven by increased shrimp and decreased high-THg fish consumption. Coastal regions exhibited the highest THg consumption due to greater blue food consumption while Northwest China displayed high-THg preferences with low overall consumption. …”

Supplementary file 1_Tapered fiber probe-based optical cardiac pacemaker.docx by Yanzheng Xie (22596953)

“…Introduction<p>The disorders of cardiac rhythm usually induce severe cardiovascular pathologies which might pose significant threats to human health. Although multiple cardiac pacing modalities have been developed, most of them face potential limitations including structural complexity, spatiotemporal imprecision and invasive implantation requirements, thereby constraining their widespread biomedical applications.…”

Height and canopy measurements of native shrubs in southern California by Emma Underwood (22077698)

“…We identified four key findings: (1) shrub biomass increased with time since last fire and the proportion of resprouting species, and decreased with distance to coast and solar radiation; (2) species with the ability to resprout (obligate resprouter and facultative seeders) contributed greater biomass at all post-fire time periods and locations when compared with obligate seeders; (3) we found higher average biomass contributed by both obligate seeder and obligate resprouter species in plots closer to the coast than interior plots; and (4) fourth, we found a significant positive relationship between woody shrub richness and biomass. …”

Data Sheet 1_Age-related white matter alterations in children with neurofibromatosis type 1: a diffusion MRI tractography study.pdf by Lisa Bruckert (6680384)

“…Compared to controls, children with NF1 had significantly increased MD and significantly decreased FA in multiple white matter pathways including the anterior thalamic radiation, cingulate, uncinate fasciculus, inferior fronto-occipital fasciculus, arcuate fasciculus, and corticospinal tract. …”

Data_Sheet_2_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The deficits in hippocampal-dependent learning and memory were accompanied by altered hippocampal neurogenesis, with an overall decrease in the proliferation and differentiation of newborn neurons within the dentate gyrus. …”

Bioassay and NMR-HSQC-Guided Isolation and Identification of Phthalide Dimers with Anti-Inflammatory Activity from the Rhizomes of Angelica sinensis by Hongyan Wen (9226895)

“…Among them, compound <b>9</b> showed a remarkable inhibitory activity with IC₅₀ values of 425 nM and could significantly decrease IL-1β and IL-6 transcription levels. …”

Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation by Huang-Ju Tu (630766)

“…Although the development of DYRK1A inhibitors has significantly advanced in recent years, the selectivity of these drugs remains a critical challenge, potentially impeding further progress. …”