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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
gene increased » center increased (Expand Search), rate increased (Expand Search), use increased (Expand Search)
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21221
Table 1_Characterization of hypoxia-related molecular clusters and prognostic riskScore for glioma.docx
Published 2025“…</p>Results<p>Our findings revealed that patients within the C1 subgroup exhibited significantly poorer prognoses, with an upregulation of genes intricately linked to various tumor progression pathways. …”
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21222
Image 2_TMEM115: a promising marker for glioma immunotherapy and prognosis.tif
Published 2025“…</p>Results<p>The results revealed a significant increase in TMEM115 expression in tumors than in non-tumor brain tissues, and knockdown of TMEM115 affects the ability of glioma cell lines to proliferate, migrate, and invade. …”
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21223
Image 1_Extreme drought shapes the gut microbiota composition and function of common cranes (Grus grus) wintering in Poyang Lake.png
Published 2024“…Additionally, functional genes related to carbohydrate metabolism, the phosphotransferase system, and the two-component systems were significantly enriched during the extreme drought year. …”
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21224
Image 7_Extreme drought shapes the gut microbiota composition and function of common cranes (Grus grus) wintering in Poyang Lake.tif
Published 2024“…Additionally, functional genes related to carbohydrate metabolism, the phosphotransferase system, and the two-component systems were significantly enriched during the extreme drought year. …”
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21225
Sequencing and assembly of the Mexican lime genome
Published 2025“…This heterozygosity can both hinder and aid efforts to study and improve these cultivars, making it increasingly clear that diploid assemblies have significant advantages over the previous generation of haploid assemblies. …”
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21226
Phenotypic divergence between hatchery pink and coho salmon and their wild counterparts
Published 2025“…These mixed results indicate significant yet variable phenotypic differences between hatchery and wild salmon in key reproductive traits. …”
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21227
Supplementary Material for: ACOT4 and ACOT6 activate Akt-mTOR pathway and inhibit calcium oxalate-induced renal tubular cell injury
Published 2025“…Furthermore, the levels of p-AKT and p-S6 decreased after ACOT4 and ACOT6 knockdown and increased following ACOT4 and ACOT6 overexpression, suggesting that both ACOT4 and ACOT6 activated Akt/mTOR signaling pathway in HK-2 cells. …”
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21228
Table 9_Bacillus velezensis 20507 promotes symbiosis between Bradyrhizobium japonicum USDA110 and soybean by secreting flavonoids.docx
Published 2025“…Flavonoids in B. velezensis fermentation broth were identified via mass spectrometry, and rutin’s regulatory effects on B. japonicum nodulation genes (NodD1/NodD2) were tested in coculture.</p>Results<p>Co-inoculation significantly increased nodulation, biomass, and N content per plant compared to single inoculations across all N levels. …”
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21229
Data Sheet 1_Spinal cord injury enhances lung inflammation and exacerbates immune response following exposure to LPS.docx
Published 2025“…Infiltration of Ly6G/C positive neutrophils and macrophages was significantly higher in SCI mice lungs post-LPS exposure. …”
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21230
DataSheet1_Cellular and transcriptomic changes by the supplementation of aged rat serum in human pluripotent stem cell-derived myogenic progenitors.DOCX
Published 2024“…</p>Results<p>We found that aged rat serum supplementation significantly reduced cell proliferation and increased cell death in both ESC- and iPSC-derived myogenic progenitors. …”
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21231
Table 4_Development of a ferroptosis-related signature and identification of NOTCH2 as a novel prognostic biomarker in pancreatic cancer.xlsx
Published 2025“…A prognostic signature was constructed using LASSO and Cox regression analysis. The role of a key gene, NOTCH2, was investigated through somatic mutation, functional enrichment, immune infiltration, and drug sensitivity analysis. …”
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21232
Image 3_Deciphering differences in microbial community characteristics and main factors between healthy and root rot-infected Carya cathayensis rhizosphere soils.jpg
Published 2024“…</p>Results<p>We found that the pH, soil organic carbon(SOC), available nitrogen (AN), available phosphorus (AP), available potassium (AK),N-acetyl-β-D-glucosaminidase (NAG) β-glucosidase (BG), fungal gene copy number, bacterial community diversity and network complexity of the diseased soil were significantly lower (p < 0.05), while Fusarium graminearum copies number levels increased (p < 0.05). …”
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21233
Table 1_Development of a ferroptosis-related signature and identification of NOTCH2 as a novel prognostic biomarker in pancreatic cancer.xlsx
Published 2025“…A prognostic signature was constructed using LASSO and Cox regression analysis. The role of a key gene, NOTCH2, was investigated through somatic mutation, functional enrichment, immune infiltration, and drug sensitivity analysis. …”
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21234
Table 1_Elevated THOC5 expression in liver cancer and its implications for tumor progression and therapeutic response.xlsx
Published 2025“…Purpose<p>Cancer remains a major global cause of death, with rising incidence influenced by environmental factors. The THOC5 gene, part of the THO complex, has emerged as a potential regulator in cancer biology. …”
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21235
Table 3_Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning.xlsx
Published 2025“…We need to further investigate the functional role of these genes and their potential in developing targeted therapies for SD and stroke patients.…”
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21236
DataSheet1_Deciphering heat wave effects on wheat grain: focusing on the starch fraction.zip
Published 2024“…Starch granule size distribution and shape were significantly altered by HW treatment, revealing an increase of A-type granules in Ardito and an opposite effect in Magueija and Bancal, while Antequera remained stable. …”
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21237
Table 1_Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning.xlsx
Published 2025“…We need to further investigate the functional role of these genes and their potential in developing targeted therapies for SD and stroke patients.…”
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21238
Table 4_Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning.xlsx
Published 2025“…We need to further investigate the functional role of these genes and their potential in developing targeted therapies for SD and stroke patients.…”
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21239
Table 1_Bacillus velezensis 20507 promotes symbiosis between Bradyrhizobium japonicum USDA110 and soybean by secreting flavonoids.xlsx
Published 2025“…Flavonoids in B. velezensis fermentation broth were identified via mass spectrometry, and rutin’s regulatory effects on B. japonicum nodulation genes (NodD1/NodD2) were tested in coculture.</p>Results<p>Co-inoculation significantly increased nodulation, biomass, and N content per plant compared to single inoculations across all N levels. …”
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21240
Data Sheet 3_NcROP2 deletion reduces Neospora caninum virulence by altering parasite stage differentiation and hijacking host immune response.csv
Published 2025“…Additionally, the NcΔROP2 mutants exhibited impaired proliferation and significantly induced the expression of interferon-stimulated genes in bovine monocyte-derived macrophages infected in vitro for 60 hours. …”