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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), greatest decrease (Expand Search)
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18021
Supplementary file 1_A cross-sectional study of the current status of psychological health and its correlation with academic performance in medical students: taking medical student...
Published 2025“…</p>Conclusion<p>The undergraduates face significant challenges in depression, anxiety, insomnia, and perceived stress, and these have negative effects on their academic performances; in particular, the depressive symptoms and perceived stress can significantly reduce their academic performances. …”
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18022
Table 3_Inequalities and age-period-cohort effects of global and regional burden for interstitial lung disease and pulmonary sarcoidosis: based on Global Burden of Disease study 20...
Published 2025“…Background<p>Interstitial lung disease (ILD) and pulmonary sarcoidosis pose significant disease burdens on a global scale.</p>Methods<p>The underlying data was derived from the Global Burden of Disease (GBD) 2021 database. …”
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18023
Table 1_Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.doc
Published 2025“…No significant differences were observed in other indicators.…”
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18024
Supplementary Material for: Non-Prescribed Use of Opioid Agonist Medications and Associations with Non-Fatal Overdoses: A Repeated Cross-Sectional Study Across a Decade of Reduced...
Published 2025“…Multinomial regression analyses showed no significant association between non-prescribed OAT use and increased risk of non-fatal overdoses. …”
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18025
Table 6_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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18026
Supplementary file 2_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…</p>Results<p>Our analysis revealed that the proportion of CCR7<sup>+</sup> Tregs decreased as the disease advanced, while the cell proportion of HLA_DR<sup>+</sup> regs escalated with the severity of the disease. …”
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18027
Data Sheet 1_High humidity environment increases FBG by impairing the intestinal barrier.zip
Published 2025“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”
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18028
Data Sheet 6_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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18029
Image 3_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o...
Published 2025“…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …”
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18030
Data Sheet 2_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx
Published 2025“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”
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18031
Data Sheet 1_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di...
Published 2025“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
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18032
Table 2_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.xlsx
Published 2025“…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…”
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18033
Neurofilament light chain as a biomarker for hereditary ATTR amyloidosis − correlation between neurofilament light chain and nerve conduction study
Published 2024“…NfL levels significantly decreased with patisiran, although no significant changes were observed in CMAP and SNAP.…”
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18034
Enamel matrix derivative in the treatment of tooth replantation: from a biological basis to clinical application
Published 2024“…Although the pooled outcomes suggested increased incidence of surface resorption (RR=1.19, <i>P</i>=0.730) and decreased risk of inflammation resorption (RR=0.68, <i>P</i>=0.560) among replanted teeth with resorption in the EMD-treated group, neither difference was statistically significant.…”
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18035
DataSheet3_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf
Published 2024“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”
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18036
Table 2_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx
Published 2025“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”
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18037
The 16S rRNA sequencing raw data for the study titled Effects of high-dose glucocorticoids on gut microbiota in the treatment of Graves' ophthalmopathy
Published 2025“…The short chain fatty acids (SCFAs)-producing ability in GO patients’ gut after high-dose GCs administration was significantly decreased. The 5-hydroxytryptamine (5-HT) levels significantly increased in gut of GO patients after administering high-dose GCs. …”
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18038
Image 2_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”
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18039
Table 1_Decadal-scale urban footprints on seagrass blue carbon dynamics in Palk Bay, India: a remote sensing based framework.docx
Published 2025“…</p>Results<p>Results indicated a significant increase in built-up area (~12 Km2) near high-impact sites (Devipattinam, Thondi), versus ~4 Km2 increase at low-impact sites (Pamban and Mandapam North). …”
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18040
Table 1_Short-term influence of Immufen™ on mild allergic rhinitis: a randomized, double-blind, placebo-controlled study.docx
Published 2024“…</p>Results<p>CQAB supplementation demonstrated a significant (P < 0.05) improvement in Total Nasal Symptom Score (TNSS) compared to placebo and CGM. …”