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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
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19841
supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma
Published 2025“…The RT‒PCR data are presented as the means ± SDs (n = 3). Statistical significance: ns, p ≥ 0.05. (right): Self-renewal capacity (n = 4) of RD cells treated with osimertinib. …”
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19842
Supplementary file 1_Effect of Bifidobacterium longum subsp. infantis YLGB-1496 on common diseases in pediatrics: a randomized, blinded, placebo-controlled trial.docx
Published 2025“…Introduction<p>Respiratory, gastrointestinal, and allergic diseases can significantly impact both the physical and mental health of children, affecting their overall quality of life. …”
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19843
MCT4/CD147 transporter complex-associated cell proliferation, migration and invasion in U87 and U251 cell lines.
Published 2024“…The curves constructed from independent experiments revealed decreased cell proliferation in MCT4 and CD147 siRNA interference cells, but increased cell proliferation in lentivirus-transduced cells. …”
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19844
Image 1_TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury.pdf
Published 2025“…In addition, TSLP treatment significantly inhibited M1 macrophage polarization and promoted M2 macrophage differentiation. …”
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19845
Supplementary Material for: Retrospective Analysis of Allergen Characteristics in Patients with Allergic Diseases in Sanmen, Zhejiang Province
Published 2025“…The positivity rate for serum total IgE was 25.67%, significantly higher than the IgE prevalence of inhalant allergens (24.84%) and food allergens (12.48%), significantly higher than the positivity rate for food allergen sIgE at 12.48% (P<0.001). …”
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19846
Table 1_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx
Published 2025“…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…”
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19847
Data Sheet 1_N-acetylcysteine reduces prefrontal reactivity to cocaine cues in individuals with cocaine use disorder.pdf
Published 2025“…While N-acetylcysteine showed no impact on subjectively rated cocaine craving, neural cue reactivity in the superior frontal gyrus was significantly decreased under N-acetylcysteine compared to placebo.…”
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19848
Effect of CO<sub>2</sub> injection on asphaltene deposition.
Published 2025“…</p><p>Conclusions/Significance</p><p>Results demonstrate that clay minerals significantly promote CO<sub>2</sub>-induced asphaltene deposition, with the deposition amount in clay-containing crude oil increasing by 37% compared to clay-free systems. …”
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19849
Table 3_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx
Published 2025“…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…”
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19850
Data Sheet 1_Artificial intelligence-assisted delineation for postoperative radiotherapy in patients with lung cancer: a prospective, multi-center, cohort study.docx
Published 2024“…In addition to better contouring accuracy, the AI-assisted delineation significantly decreased the consuming time and improved the efficiency.…”
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19851
Supplementary file 1_To assess the impact of individualized strategy and continuous glucose monitoring on glycemic control and mental health in pregnant women with diabetes.docx
Published 2025“…</p>Results<p>FBG and 2hPBG significantly decreased post-intervention in both groups (P<0.001). …”
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19852
Table 1_Exhaled breath particles as a diagnostic tool for bronchiolitis obliterans syndrome in lung transplant recipients: a longitudinal study.docx
Published 2025“…The particle distribution between the different BOS grades had a similar pattern; however, it significantly decreased PFR with severity in the BOS grade.…”
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19853
Table 4_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx
Published 2025“…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…”
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19854
Table 1_Inflammatory markers CRP and WBC as predictors of liver function impairment in multiple injury trauma patients: a repeated measures analysis.docx
Published 2025“…</p>Results<p>Elevated CRP levels significantly correlated with increased AST (OR = 2.17, 95% CI: 1.14–4.12, p = 0.019) and ALT (OR = 2.37, 95% CI: 1.22–4.63, p = 0.011). …”
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19855
Effect of clay content on IFT.
Published 2025“…</p><p>Conclusions/Significance</p><p>Results demonstrate that clay minerals significantly promote CO<sub>2</sub>-induced asphaltene deposition, with the deposition amount in clay-containing crude oil increasing by 37% compared to clay-free systems. …”
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19856
Table 2_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx
Published 2025“…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…”
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19857
Data Sheet 1_Susceptibility to and severity of tuberculosis infection in mice depends upon MHC-II-determined level of activation-inhibition balance in CD4 T-cells.pdf
Published 2025“…<p>Previously we have shown that H2-congenic recombinant mice of the B6.I-9.3 (H2-Ab1<sup>j</sup>) strain are significantly more susceptible to tuberculosis (TB) infection compared to their C57BL/6 (B6, H2-A<sup>b</sup>) ancestors. …”
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19858
Effect of clay content on crude oil viscosity.
Published 2025“…</p><p>Conclusions/Significance</p><p>Results demonstrate that clay minerals significantly promote CO<sub>2</sub>-induced asphaltene deposition, with the deposition amount in clay-containing crude oil increasing by 37% compared to clay-free systems. …”
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19859
Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx
Published 2025“…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”
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19860
Effect of pressure on asphaltene deposition.
Published 2025“…</p><p>Conclusions/Significance</p><p>Results demonstrate that clay minerals significantly promote CO<sub>2</sub>-induced asphaltene deposition, with the deposition amount in clay-containing crude oil increasing by 37% compared to clay-free systems. …”