Data Sheet 1_Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis.zip by Dongmei Yuan (291583)

“…<p>Visceral leishmaniasis (VL), the most severe form of leishmaniasis, remains a significant public health concern that cannot be overlooked in underdeveloped regions. …”

Supplementary file 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.docx by Susan Carroll (17468)

“…Participants reported significant benefits from nature.</p>Discussion<p>Overall, the results showed that connecting with nature significantly contributes to flourishing in highly sensitive individuals, particularly in middle to older age. …”

Image 2_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif by Zechen Zhang (11702123)

“…C-terminal telopeptide (CTX) showed a small, statistically significant reduction (MD −0.09, 95% CI −0.14 to −0.05) with uncertain clinical relevance. …”

Image 5_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg by Yue Fu (64387)

“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”

Image 3_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png by Xiaofang Chen (256976)

“…</p>Results<p>In 2019, lead exposure-related ischemic stroke caused a significant disease burden, with males and middle-aged/older adults disproportionately affected. …”

<i>Neisseria</i> species on the tonsillar surface predicts favorable clinical outcomes in patients with Immunoglobulin A nephropathy who underwent tonsillectomy by Ryosuke Sato (615801)

“…However, there were no significant differences in the clinical course, except for renal survival rates, between patients with and without <i>Neisseria</i> sp. at the tonsillar center. …”

Data Sheet 2_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... by Zhe Sun (328682)

“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”

Identifying hotspots of urbanization and agricultural growth: a spatio-temporal analysis of land use dynamics in Tolga, Algeria (1994–2024) by Mohamed Akram Eddine Ben Ratmia (21662098)

“…<p>Land use and land cover (LULC) changes driven by urbanization and agricultural expansion pose significant challenges to biodiversity, water resources, and sustainable development, particularly in arid and semi-arid regions. …”

Image 1_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png by Xiaofang Chen (256976)

“…</p>Results<p>In 2019, lead exposure-related ischemic stroke caused a significant disease burden, with males and middle-aged/older adults disproportionately affected. …”

Data Sheet 6_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... by Zhe Sun (328682)

“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”

Data Sheet 1_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... by Zhe Sun (328682)

“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”

Image 8_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg by Yue Fu (64387)

“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”

Supplementary file 1_Mechanism of soil microbial community degradation under long-term tomato monoculture in greenhouse.docx by Menglu Li (4458208)

“…<p>Tomato (Solanum lycopersicum L.), an economically significant crop, is frequently cultivated in greenhouses under continuous monoculture systems. …”

Table 6_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx by M. Virginia Martín (6321047)

“…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …”

Table 1_Differences in the dynamic balance function of healthy elementary school students and university students observed with and without the use of a sensor-integrated gamificat... by Yasuaki Kusumoto (2634931)

“…</p>Results<p>During the Y-Balance test, all items exhibited no significant interaction effects; however, several outcome measures exhibited main effects. …”

Do policy uncertainty and volatility index affect dynamic connectedness among house price, financial and commodity market indices? Evidence from TVP-VAR and quantile regression ana... by Nilotpal Sarma (21460739)

“…Moreover, at higher quantiles, an increase in policy uncertainty and equity-market risk decreases the net connectedness of the house price index. …”

Data Sheet 1_Age and growth of Todaropsis eblanae (Ommastrephidae) through comparison of statoliths, beaks and eye lenses.docx by Blondine Agus (10990749)

“…Both sexes showed a higher initial growth rate, which gradually decreases, with the highest values at the age of 101-151 days, before reaching sexual maturity. …”

<b><i>Streptococcus suis</i></b><b> </b><b>s</b><b>erotype</b><b> 5</b><b>: emerging </b><b>zoonotic </b><b>threat</b><b> with </b><b>distinct</b><b> genomic heterogeneity</b> by han zheng (20452463)

“…<p dir="ltr"><i>Streptococcus suis</i> is a significant pig pathogen and an emerging zoonotic agent. …”

Table 1_Cytokine dynamics in the blood and cerebrospinal fluid of HIV/AIDS patients with cryptococcal meningitis receiving antifungal therapy.docx by Rui Su (822125)

“…Over 28 days of antifungal treatment, significant decreases in the CSF levels of IL-2 and IL-10 and the plasma levels of IL-10 and IL-4 were observed. …”

Supplementary Material for: Clinical and Experimental Insights into the Role of NETosis in IgA Nephropathy Pathogenesis by figshare admin karger (2628495)

“…RNA sequencing identified 905 DEGs in IgAN patients, with significant enrichment in neutrophil and NETosis pathways. …”