Supplementary file 1_Assessment of suitability evaluation for Ficus altissima blume ancient trees in different climatic environments in Guangxi, China.docx by Hongliang Gu (21671054)

“…Introduction<p>The Guangxi Zhuang Autonomous Region of China is home to numerous Ficus altissima Blume (F. altissima) ancient trees over 300 years old, which hold significant cultural, ecological, and scientific research value. …”

Video 1_Efficacy of a novel surgical approach: sutureless correction of conjunctivochalasis using new conjunctival forceps combined with high-frequency electrocautery.mp4 by Tingting Song (575707)

“…OSDI scores showed no difference between preoperative (38.54) and 1-week postoperative (41.67) values (p=0.922), but significantly decreased by 1 month (16.67, p<0.001). …”

Table 3_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.xlsx by Giuseppe G. F. Leite (18186056)

“…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …”

Data Sheet 3_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf by Shiqiu Xiong (238109)

“…Physical examination revealed abdominal tenderness and decreased bowel sounds. Contrast x-ray showed an obstructed passage of contrast through the third part of the duodenum. …”

Table 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.docx by Jinque Luo (9645983)

“…Introduction<p>Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage. …”

Image 5_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tiff by Inssaf Berkiks (15350248)

“…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”

DataSheet1_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …”

Image 1_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff by Wei-wei Zhu (20349897)

“…An elevated peak EDVi/E/e’ and a decreased ΔSVi are independent risk factors for exercise intolerance in patients with CCS.…”

Data Sheet 8_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”

Image 4_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg by Chaofeng Niu (17746406)

“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”

Table 2_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Supplementary Material for: The role of reactive oxygen species in the pathogenesis of alopecia areata: a systematic review and meta-analysis. by Perlmutter J. (11590717)

“…Background: Alopecia areata (AA) is a T-cell-mediated autoimmune disease that significantly impacts patient quality of life. The breakdown of hair follicle immune privilege underlies AA pathogenesis. …”

Image 2_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff by Wei-wei Zhu (20349897)

“…An elevated peak EDVi/E/e’ and a decreased ΔSVi are independent risk factors for exercise intolerance in patients with CCS.…”

Data Sheet 2_Astragalus polysaccharide modulates the gut microbiota and metabolites of patients with major depressive disorder in an in vitro fermentation model: a pilot study.xlsx by Yuwei Mi (18003969)

“…APS fermentation increased the abundance of Bifidobacterium and decreased the abundance of Lachnoclostridium (p < 0.05). …”

Assessment of soil erosion risks and prioritizing nature-based conservation practices using RUSLE, geospatial techniques and household surveys in central Ethiopia by Gamachu Yadata Nugusa (22683061)

“…The HHS and FO results align with the model findings, confirming that the SEHS decreases. These findings can inform policymakers, strengthen NBS, and guide targeted interventions. …”

Model comparison experimental results. by Chunhua Yang (346871)

“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”

DataSheet3_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …”

<b>Patterns</b><b> and drivers of </b><b>plant C:N:P stoichiometry</b><b> across a 3000 km aridity gradient</b> by Jianzhao Wu (19185964)

“…Below this threshold (AI < 0.7), the leaf C:P and N:P ratios decreased as AI increased, and N limitation became more evident. …”

Supplementary file 6_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf by Yanling Wen (552195)

“…</p>Results<p>Our analysis revealed that the proportion of CCR7⁺ Tregs decreased as the disease advanced, while the cell proportion of HLA_DR⁺ regs escalated with the severity of the disease. …”

Image_2_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.PNG by Weiran Lv (715679)

“…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …”