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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greater increase » year increase (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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20141
Image 1_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif
Published 2025“…C-terminal telopeptide (CTX) showed a small, statistically significant reduction (MD −0.09, 95% CI −0.14 to −0.05) with uncertain clinical relevance. …”
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20142
Table 5_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx
Published 2025“…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …”
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20143
Supplementary file 3_Practical utility of meropenem therapeutic drug monitoring: a systematic review of evidence for clinical application.docx
Published 2025“…CRP levels decreased significantly (mean difference = 14.91; 95% CI: 2.79–27.02), while changes in PCT, WBC, and neutrophil ratios were non-significant. …”
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20144
Table 1_Dietary caffeine and its negative link to serum Klotho concentrations: evidence from the National Health and Nutrition Examination Survey.docx
Published 2024“…Subgroup analyses indicated that this association was more significant in participants with sedentary activity >480 min and without hypertension.…”
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20145
Table 1_Elevated mean arterial pressure and risk of impaired fasting glucose: a multicenter cohort study revealing age and sex interactions.docx
Published 2025“…Multivariate smooth splines analysis revealed a nonlinear relationship (P for nonlinearity < 0.05), with the curve slope decreasing as MAP exceeded 103.23 mmHg. Significant interaction effects between MAP and age or sex on IFG risk were also identified (P < 0.05).…”
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20146
Image 2_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png
Published 2025“…</p>Results<p>In 2019, lead exposure-related ischemic stroke caused a significant disease burden, with males and middle-aged/older adults disproportionately affected. …”
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20147
Supplementary file 1_Practical utility of meropenem therapeutic drug monitoring: a systematic review of evidence for clinical application.docx
Published 2025“…CRP levels decreased significantly (mean difference = 14.91; 95% CI: 2.79–27.02), while changes in PCT, WBC, and neutrophil ratios were non-significant. …”
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20148
5OMV Inhibits HMGB1-Induced Microvascular Branch Formation in Rat Abdominal Aortic Rings.
Published 2025“…Mean values showing significant differences between the control group and the HMGB1-treated group are indicated by *(<i>P</i> < 0.05) or ** (<i>P</i> < 0.01). …”
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20149
Data Sheet 1_Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas.pdf
Published 2025“…Attention scores also decreased at 800 meters (94.4%, p = 0.002). No significant changes were found in parietal, temporal, or occipital lobe functions. …”
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20150
Table 1_Depression score and body mass index mediate the association between dietary vitamin C intake and female infertility: a study based on NHANES 2013–2018.xlsx
Published 2025“…A threshold non-linear association between VC and infertility was more significant in women aged from 18 to 34 (P = 0.033). …”
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20151
Table 2_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx
Published 2025“…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …”
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20152
Table 1_Global, regional, and national burden of liver cancer in adolescents and young adults from 1990 to 2021: an analysis of the global burden of disease study 2021 and forecast...
Published 2025“…East Asia bears the highest burden, with males experiencing significantly higher rates than females. The burden increases with age, peaking at 35–39 years. …”
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20153
Image 7_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg
Published 2025“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”
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20154
Data Sheet 1_Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice.zip
Published 2025“…WB showed that P62 was significantly increased and RILP was significantly decreased in diabetic mice subjected to I/RI compared to healthy mice. …”
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20155
Data Sheet 2_Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas.pdf
Published 2025“…Attention scores also decreased at 800 meters (94.4%, p = 0.002). No significant changes were found in parietal, temporal, or occipital lobe functions. …”
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20156
Image 1_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg
Published 2025“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”
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20157
Table 1_A daily positive work reflection intervention for psychological distress among Chinese nurses: a pilot randomized controlled trial.docx
Published 2025“…</p>Results<p>In addition to significant within group improvements over time for both groups, OLS linear regression with Full Information Likelihood Estimation revealed a statistically significant between group treatment effects across outcome domains, including psychological distress, b = 22.60, p < 0.001, g = 11.34, somatic symptoms, b = 6.79, p < 0.001, g = 6.56, depressive symptoms, b = 8.15, p < 0.001, g = 8.19, and anxiety symptoms, b = 7.69, p < 0.001, g = 8.23.…”
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20158
Table 1_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.docx
Published 2025“…C-terminal telopeptide (CTX) showed a small, statistically significant reduction (MD −0.09, 95% CI −0.14 to −0.05) with uncertain clinical relevance. …”
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20159
Image 1_Depression score and body mass index mediate the association between dietary vitamin C intake and female infertility: a study based on NHANES 2013–2018.tif
Published 2025“…A threshold non-linear association between VC and infertility was more significant in women aged from 18 to 34 (P = 0.033). …”
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20160
Data Sheet 2_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip
Published 2025“…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …”