Data Sheet 1_Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study.docx by Li Jiang (120930)

“…Background<p>Diabetic Kidney Disease (DKD) is a serious complication of diabetes, imposing a substantial medical burden. The significance of N6-methyladenosine (m6A) modification in the pathogenesis of DKD has become increasingly prominent.…”

Table_1_Ontogeny and brooding strategy of the early Cambrian arthropod Isoxys minor from the Qingjiang biota.XLSX by Jiaxin Ma (3847726)

“…Quantitative analysis of shape changes during growth using 51 specimens of †I. minor from the Qingjiang biota, reveals that its valves gradually elongate and the ratio of cardinal spines and spherical eyes relative to the valve length significantly decreases during postembryonic development. …”

Data from: Functional response comparisons among freshwater amphipods: ratio-dependence and higher predation for Gammarus pulex compared to the non-natives Dikerogammarus villosus... by Vincent Medoc (593571)

“…Time spent interacting with conspecifics is likely to decrease the biotic pressure of the Killer shrimp D. villosus. …”

Data_Sheet_5_Iron Deficiency Leads to Chlorosis Through Impacting Chlorophyll Synthesis and Nitrogen Metabolism in Areca catechu L..XLSX by Jia Li (160557)

“…However, both excessive and deficient of iron decreases fresh weight and photosynthetic rate in A. catechu seedlings. …”

DataSheet1_Transcription start site signal profiling improves transposable element RNA expression analysis at locus-level.PDF by Natalia Savytska (13991031)

“…As a remedy, filtering based on the minimum number of read counts or baseMean expression improves the F1 score and decreases the number of false positives. Finally, we demonstrate that additional profiling of Transcription Start Site mapping statistics (using a k-means clustering approach) significantly improves the performance of TElocal while reporting a reliable set of detected and differentially expressed TEs in human simulated RNA-seq data.…”

Image_2_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.jpeg by Jacob MacWilliams (5040044)

“…This suggests that other cannabinoids and/or metabolites such as terpenes are causing the observed decrease in aphid performance in the whole plant assays. …”

Overexpression of chitinase <i>PbChia1</i> from <i>Plasmodiophora brassicae</i> improves broad-spectrum disease resistance of Arabidopsis by Yanli Zhao (462683)

“…PbChia1 was found to be a typical secreted chitinase, which could bind chitin with chitinase activity <i>in vitro</i>. PbChia1 could significantly decrease the resting spores of <i>P. brassicae</i> and therefore relieve the severity of clubroot symptom, with a biocontrol effect of 61.29%. …”

Image_1_A Systematic Review and Meta-Analysis of Minimally Invasive Partial Nephrectomy Versus Focal Therapy for Small Renal Masses.jpeg by Lin Dong (1458793)

“…Compared with MIPN, the operating time (OP) of FT had significantly lower (SMD, −1.20; CI, −1.77 to −0.63; I² = 97.6%, P < 0.0001), estimated blood loss (EBL) of FT had significantly less (SMD, −1.20; CI, −1.77 to −0.63; I² = 97.6%, P < 0.0001), length of stay (LOS) had shorter (SMD, −0.90; CI, −1.26 to −0.53; I² = 92.2%, P < 0.0001), and estimated glomerular filtration rate (eGFR) of FT was significantly lower decrease (SMD, −0.90; CI, −1.26 to −0.53; I² = 92.2%, P < 0.0001). …”

DataSheet_1_v1_A Systematic Review and Meta-Analysis of Minimally Invasive Partial Nephrectomy Versus Focal Therapy for Small Renal Masses.pdf by Lin Dong (1458793)

“…Compared with MIPN, the operating time (OP) of FT had significantly lower (SMD, −1.20; CI, −1.77 to −0.63; I² = 97.6%, P < 0.0001), estimated blood loss (EBL) of FT had significantly less (SMD, −1.20; CI, −1.77 to −0.63; I² = 97.6%, P < 0.0001), length of stay (LOS) had shorter (SMD, −0.90; CI, −1.26 to −0.53; I² = 92.2%, P < 0.0001), and estimated glomerular filtration rate (eGFR) of FT was significantly lower decrease (SMD, −0.90; CI, −1.26 to −0.53; I² = 92.2%, P < 0.0001). …”

Photothermal therapy co-localized with CD137 agonism improves survival in an SM1 melanoma model without hepatotoxicity by Jacob A Medina (19530945)

“…</p> <p>αCD137-PBNP-PTT effectively treats SM1 tumors <i>in vivo</i> by decreasing tumor growth and significantly improving mouse survival.…”

Image5_Effectiveness and safety of brucea javanica oil assisted TACE versus TACE in the treatment of liver cancer: a systematic review and meta-analysis of randomized controlled tr... by Zhi-Hai Wu (13197603)

“…Furthermore, AFP improvement rate improved significantly by approximately 134% [RR = 2.34, 95% CI (1.58, 3.46)], accompanied by notable improvements in liver function indicators, with an average reduction of 27.19 U/L in AST [MD = −27.19, 95% CI (−40.36, −14.02)], 20.77 U/L in ALT [MD = −20.77, 95% CI (−39.46, −2.08)], 12.17 μmol/L in TBIL [MD = −12.17, 95% CI (−19.38, −4.97)], and a decrease of 43.72 pg/mL in VEGF [MD = −43.72, 95% CI (−63.29, −24.15)]. …”

Image3_Effectiveness and safety of brucea javanica oil assisted TACE versus TACE in the treatment of liver cancer: a systematic review and meta-analysis of randomized controlled tr... by Zhi-Hai Wu (13197603)

“…Furthermore, AFP improvement rate improved significantly by approximately 134% [RR = 2.34, 95% CI (1.58, 3.46)], accompanied by notable improvements in liver function indicators, with an average reduction of 27.19 U/L in AST [MD = −27.19, 95% CI (−40.36, −14.02)], 20.77 U/L in ALT [MD = −20.77, 95% CI (−39.46, −2.08)], 12.17 μmol/L in TBIL [MD = −12.17, 95% CI (−19.38, −4.97)], and a decrease of 43.72 pg/mL in VEGF [MD = −43.72, 95% CI (−63.29, −24.15)]. …”

Image_5_MNX (Medium Duration Nutrition and Resistance-Vibration Exercise) Bed-Rest: Effect of Resistance Vibration Exercise Alone or Combined With Whey Protein Supplementation on C... by Patrick Guinet (20528)

“…In the 3 groups, (1) OT time dropped similarly (bed rest p < 0.001), (2) HR and ΣI were increased at rest at the end of HDBR and HR increased markedly during LBNP-tilt test, with inability to increase further the ΣI, (3) PV dropped (bed rest p < 0.001), along with LVEDV, LVESV and SV (p = 0.08, p < 0.001, and p = 0.045, respectively), (4) Left ventricle mass did not change significantly, (5) Deformation of the heart assessed by global circumferential strain was preserved and early diastolic circumferential strain rate was increased during orthostatic stress at the end of HDBR, illustrating preserved systolic and diastolic function respectively, without any difference between groups. …”

Supplementary file 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burd... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”

Image4_Effectiveness and safety of brucea javanica oil assisted TACE versus TACE in the treatment of liver cancer: a systematic review and meta-analysis of randomized controlled tr... by Zhi-Hai Wu (13197603)

“…Furthermore, AFP improvement rate improved significantly by approximately 134% [RR = 2.34, 95% CI (1.58, 3.46)], accompanied by notable improvements in liver function indicators, with an average reduction of 27.19 U/L in AST [MD = −27.19, 95% CI (−40.36, −14.02)], 20.77 U/L in ALT [MD = −20.77, 95% CI (−39.46, −2.08)], 12.17 μmol/L in TBIL [MD = −12.17, 95% CI (−19.38, −4.97)], and a decrease of 43.72 pg/mL in VEGF [MD = −43.72, 95% CI (−63.29, −24.15)]. …”

Image_4_MNX (Medium Duration Nutrition and Resistance-Vibration Exercise) Bed-Rest: Effect of Resistance Vibration Exercise Alone or Combined With Whey Protein Supplementation on C... by Patrick Guinet (20528)

“…In the 3 groups, (1) OT time dropped similarly (bed rest p < 0.001), (2) HR and ΣI were increased at rest at the end of HDBR and HR increased markedly during LBNP-tilt test, with inability to increase further the ΣI, (3) PV dropped (bed rest p < 0.001), along with LVEDV, LVESV and SV (p = 0.08, p < 0.001, and p = 0.045, respectively), (4) Left ventricle mass did not change significantly, (5) Deformation of the heart assessed by global circumferential strain was preserved and early diastolic circumferential strain rate was increased during orthostatic stress at the end of HDBR, illustrating preserved systolic and diastolic function respectively, without any difference between groups. …”

Image1_Effectiveness and safety of brucea javanica oil assisted TACE versus TACE in the treatment of liver cancer: a systematic review and meta-analysis of randomized controlled tr... by Zhi-Hai Wu (13197603)

“…Furthermore, AFP improvement rate improved significantly by approximately 134% [RR = 2.34, 95% CI (1.58, 3.46)], accompanied by notable improvements in liver function indicators, with an average reduction of 27.19 U/L in AST [MD = −27.19, 95% CI (−40.36, −14.02)], 20.77 U/L in ALT [MD = −20.77, 95% CI (−39.46, −2.08)], 12.17 μmol/L in TBIL [MD = −12.17, 95% CI (−19.38, −4.97)], and a decrease of 43.72 pg/mL in VEGF [MD = −43.72, 95% CI (−63.29, −24.15)]. …”

Image_1_MNX (Medium Duration Nutrition and Resistance-Vibration Exercise) Bed-Rest: Effect of Resistance Vibration Exercise Alone or Combined With Whey Protein Supplementation on C... by Patrick Guinet (20528)

“…In the 3 groups, (1) OT time dropped similarly (bed rest p < 0.001), (2) HR and ΣI were increased at rest at the end of HDBR and HR increased markedly during LBNP-tilt test, with inability to increase further the ΣI, (3) PV dropped (bed rest p < 0.001), along with LVEDV, LVESV and SV (p = 0.08, p < 0.001, and p = 0.045, respectively), (4) Left ventricle mass did not change significantly, (5) Deformation of the heart assessed by global circumferential strain was preserved and early diastolic circumferential strain rate was increased during orthostatic stress at the end of HDBR, illustrating preserved systolic and diastolic function respectively, without any difference between groups. …”

Table 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”

Table 2_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”