Image 5_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg by Chaofeng Niu (17746406)

“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”

Image 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf by Maxim Sorokin (4379848)

“…We detected no statistically significant difference in the number of chimeric transcripts in FFPE and FF RNAseq profiles. …”

Workflow of the study. by Hongliang Chen (538815)

“…Enrichment and immune infiltration analyses revealed significant differences in mitochondrial structure and function, immune cell disorders, and signaling pathway activation between the high- and low-mitochondrial gene expression UC groups. …”

Table 1_Proteomic insights into COPD pathogenesis and therapeutic targets: a causal analysis of circulating proteins.docx by Min Luo (258201)

“…Western blot analysis validated these findings in plasma samples, showing significantly increased expression of MMP12 and ASM, and decreased expression of NPNT and SNX1 in COPD patients compared to healthy controls, while KLC1 showed no significant difference. …”

DataSheet8_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.zip by Yongming Du (807059)

“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”

Data Sheet 1_From psychological wellbeing to distress: the role of psychological counseling interventions in university students.pdf by Francesco Craig (8214780)

“…Post-intervention, psychological distress decreased significantly (p < 0.001), with 56.7% of students falling over the clinical distress cut-off at T1 compared to 84.4% at T0. …”

What is the optimal In2Care stations density to achieve Aedes aegypti population reduction in a dengue endemic setting? by Rafael Freitas (16738416)

“…</p><p dir="ltr"><b>Conclusions/Significance:</b> The density of In2Care stations varied across neighborhoods, ranging from 220 to 555 stations per km². …”

Table 1_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.docx by Guojie Ji (21518650)

“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”

Scaling analyses and morphometrics of <i>Ginkgo biloba</i> seeds by Wen Gu (129075)

“…When seeds were grouped by the ellipsoid index (EI = <i>V</i>/<i>V</i>_E), the scaling exponent of <i>V</i> vs. <i>M</i> decreased from values significantly greater than one to values less than one as EI increased. …”

Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease by Halil Onder (10368032)

“…The comparative analyses between medication-off and -on states revealed that the MDS-UPDRS-3 scores decreased significantly during the medication-on states (<i>p</i> < 0.001, d = 1.09). …”

Data_Sheet_1_Correlation between body mass index and gender-specific 28-day mortality in patients with sepsis: a retrospective cohort study.docx by Chong Li (120471)

“…</p>Results<p>The BMI and 28-day mortality exhibited an L-shaped relationship (p for nonlinearity <0.001) with significant gender-specific differences. Subgroup analysis revealed different association patterns between the male and female cohorts. …”

Table 2_Role of miR-144-5p in modulating lipid metabolism and potentially alleviating obesity via the PGC-1α/AMPK pathway.xlsx by Siriguleng Yu (14555900)

“…</p>Results<p>The treatment significantly reduced diet-induced adiposity and decreased inflammatory responses. …”

Table 2_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx by Zhengqing Yu (12641890)

“…Significant heterogeneity was detected in the pooled analysis and meta-regression analysis suggested that participants’ age and the prevalence of diabetes significantly accounted for the heterogeneity.…”

Neurodevelopmental H2AK119ub enrichment within H3K4me3-positive promoters subdues transcription. by Aditya Parmar (22331873)

“…<b>(J)</b> RNAseq data within genes possessing H3K4me3-only promoters that experienced a significant increase in H2AK119ub. <b>(K)</b> RNAseq data within genes possessing bivalent promoters that experienced a significant increase in H2AK119ub. …”

Table 1_Trends in diet structural composition and quality among adults in Beijing, China (2010–2022).docx by Ningsu Chen (18014155)

“…Between 2010 and 2022, carbohydrate contribution to energy intake decreased from 56.1 to 46.7%, whereas fat intake increased from 31.6 to 36.9%. …”

Table 2_Effects of supplementation with vitamin D3 on growth performance, lipid metabolism and cecal microbiota in broiler chickens.docx by Jiawei Li (559407)

“…Supplementary VD₃ significantly enhanced average daily gain (ADG) in broilers aged 57-84 d and 1-84 d, and increased leg muscle rate and fat content in breast and leg muscles and reduced abdominal fat rate of broilers at 84 d. …”

Table 1_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.xlsx by Ying Liu (18461)

“…Background<p>Esophageal cancer remains one of the deadliest cancers globally, highlighting significant health challenges and socioeconomic disparities. …”

Image3_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg by Saeko Yamada (11899439)

“…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…”

Table 1_Effects of two kinds of vestibular function training on reducing motion sickness in college students.docx by Linyao Shi (20684204)

“…</p>Results<p>After training, both groups’ Graybiel scores, blood pressure, high-frequency power (HF), and root mean square of successive differences (rMSSD) between adjacent normal heartbeats significantly decreased. In the visual-motion cage rotating chair group, in addition to a reduction in the percentage of adjacent normal-to-normal intervals which differed by more than 50 ms (pNN50), as well as decreases in low-frequency power (LF), an increase in LF/HF was observed. …”

Effects of nano-curcumin on cell cycle and apoptosis in breast cancer cells. by Taraneh Givi (22793530)

“…The expression levels of <i>CCNA2</i> and <i>CCND1</i> were significantly decreased in both MCF7-S and MCF7-TR cells following nano-curcumin treatment. …”