Search alternatives:
significant activation » significant alterations (Expand Search), significant attention (Expand Search), significant variation (Expand Search)
activation increases » activation energies (Expand Search), activity increased (Expand Search)
i decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
significant activation » significant alterations (Expand Search), significant attention (Expand Search), significant variation (Expand Search)
activation increases » activation energies (Expand Search), activity increased (Expand Search)
i decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Loss of <i>Nf1</i> increases sleep fragmentation and decreases sleep depth.
Published 2023“…Compared to control and heterozygote flies, arousal threshold significantly decreases in <i>nf1</i><sup>P1</sup> mutants and occurs during the day (+, <i>P</i><0.0001; het, <i>P</i><0.0001) and night (+, <i>P</i><0.0001; het, <i>P</i><0.0001). …”
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”
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Loss of <i>Nf1</i> decreases sleep and increases metabolic rate in the SAMM system.
Published 2023“…Compared to controls, pan-neuronal knockdown of <i>Nf1</i> significantly decreases sleep during the day (nsyb/+, <i>P</i><0.0001; <i>Nf1</i><sup>RNAi</sup>/+, <i>P</i><0.0001), but not the night (nsyb/+, <i>P</i><0.3333; <i>Nf1</i><sup>RNAi</sup>/+, <i>P</i><0.2203). …”
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PGRN decreased Dectin-2 expression on the surface of macrophages and neutrophils.
Published 2022Subjects: -
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Increased phospholipase activity in MDR-TB.
Published 2021“…<p>Volcano plots of plasma lipids with confirmed chemical identities shows significant increases of lyso-phospholipids and significant decreases in phospholipids with two acyl chains in persons with MDR-TB with (n = 29) and without (n = 21) HIV co-infection versus (A) persons with latent TB infection (n = 20) and (B) persons with drug susceptible (DS)-TB (n = 30). …”